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Those with eating disorders (EDs) frequently have complex patterns of comorbid symptoms and the transdiagnostic theory includes shared common core features across diagnoses. We aim to test whether general psychiatric symptoms comprise components of these transdiagnostic features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Network analysis was applied on 2068 patients with EDs (955 anorexia nervosa [AN], 813 bulimia nervosa [BN], and 300 binge\u2010eating disorder [BED]). All patients underwent clinical interviews and some self\u2010reported questionnaires, such as the Symptom Check\u2010List 90 (SCL\u201090) to measure psychiatric symptoms, the Eating Disorder Inventory (EDI) to measure ED\u2010specific symptoms, and the Tridimensional Personality Questionnaire (TPQ) for personality traits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Across EDs and within each ED, SCL\u201090 scores of depression, anxiety and interpersonal sensitivity, EDI ineffectiveness, interoceptive awareness, interpersonal distrust, and drive for thinness had high centrality. Notably, body mass index (BMI) and EDI bulimia played a central role when considering the whole group, whereas they did not in individual EDs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The shared centrality of identified nodes in both individual and merged groups supported the transdiagnostic theory of EDs (diagnoses share core ED features), with a central role of BMI. Moreover, the most central nodes were general psychiatric symptoms, interpersonal domain, and self\u2010efficacy. These findings suggest that\u2014in addition to ED\u2010core symptoms and BMI\u2014depressive and anxiety symptoms, interpersonal sensitivity and ineffectiveness may be important targets to provide effective treatments across AN, BN, and BED.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.22884","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T09:20:36Z","timestamp":1527672036000},"page":"680-692","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":111,"title":["Network analysis of specific psychopathology and psychiatric symptoms in patients with eating disorders"],"prefix":"10.1002","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4877-7233","authenticated-orcid":false,"given":"Marco","family":"Solmi","sequence":"first","affiliation":[{"name":"Neuroscience Department, Psychiatry Unit University of Padua Padua Italy"},{"name":"Psychiatry Unit, Padua University Hospital Padua 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