{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T09:01:33Z","timestamp":1778317293242,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,1,12]],"date-time":"2020-01-12T00:00:00Z","timestamp":1578787200000},"content-version":"am","delay-in-days":365,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2019,1,12]],"date-time":"2019-01-12T00:00:00Z","timestamp":1547251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["NSF 1449440"],"award-info":[{"award-number":["NSF 1449440"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH\u201010\u20102\u20100181"],"award-info":[{"award-number":["W81XWH\u201010\u20102\u20100181"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH\u201016\u20102\u20100003"],"award-info":[{"award-number":["W81XWH\u201016\u20102\u20100003"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["VR Dnr: 538\u20102013\u20108864"],"award-info":[{"award-number":["VR Dnr: 538\u20102013\u20108864"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["VR Dnr: 538\u20102013\u20108864"],"award-info":[{"award-number":["VR Dnr: 538\u20102013\u20108864"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study examined a hypothesized pathway by which interoceptive dysfunction accounted for associations between personality features (harm avoidance, self\u2010directedness, and perfectionism) and anorexia nervosa (AN) severity (indicated by drive for thinness, eating disorder\u2010related preoccupations and rituals, and body mass index).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The study sample (<jats:italic>n<\/jats:italic>\u2009=\u2009270, mean age\u2009=\u200928.47, 95.2% female, 98% White\/Caucasian) consisted of probands and biological relatives who met DSM\u2010IV criteria for lifetime diagnoses of AN (omitting criterion D, amenorrhea) drawn from the Price Foundation Anorexia Nervosa Affected Relative Pairs Study (AN\u2010ARP). Participants completed measures assessing personality, interoceptive dysfunction, and eating pathology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Associations between personality features of low self\u2010directedness and high perfectionism and indicators of AN severity (drive for thinness and eating disorder\u2010related preoccupations and rituals) were significant, as were the hypothesized indirect pathways through interoceptive dysfunction. Neither harm avoidance nor body mass index was significantly related to other study variables, and the proposed indirect pathways involving these variables were not significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Findings suggest that certain personality features may relate to AN severity, in part, through their associations with interoceptive dysfunction. Future research should examine prospective associations and the value of interventions targeting interoceptive dysfunction for interrupting the link between personality and AN severity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23008","type":"journal-article","created":{"date-parts":[[2019,1,12]],"date-time":"2019-01-12T10:13:01Z","timestamp":1547287981000},"page":"200-205","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["An investigation of indirect effects of personality features on anorexia nervosa severity through interoceptive dysfunction in individuals with lifetime anorexia nervosa diagnoses"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7045-699X","authenticated-orcid":false,"given":"Mary E.","family":"Duffy","sequence":"first","affiliation":[{"name":"Department of Psychology Florida State University  Tallahassee Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4969-7035","authenticated-orcid":false,"given":"Megan L.","family":"Rogers","sequence":"additional","affiliation":[{"name":"Department of Psychology Florida State University  Tallahassee Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6798-9085","authenticated-orcid":false,"given":"Thomas E.","family":"Joiner","sequence":"additional","affiliation":[{"name":"Department of Psychology Florida State University  Tallahassee Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew W.","family":"Bergen","sequence":"additional","affiliation":[{"name":"BioRealm, LLC  Walnut California"},{"name":"Oregon Research Institute  Eugene Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wade","family":"Berrettini","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia M.","family":"Bulik","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of North Carolina at Chapel Hill  Chapel Hill North Carolina"},{"name":"Department of Nutrition University of North Carolina at Chapel Hill  Chapel Hill North Carolina"},{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry","family":"Brandt","sequence":"additional","affiliation":[{"name":"Sheppard Pratt Health System  Towson Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Crawford","sequence":"additional","affiliation":[{"name":"Sheppard Pratt Health System  Towson Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1827-5075","authenticated-orcid":false,"given":"Scott","family":"Crow","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Minnesota Medical School  Minneapolis Minnesota"},{"name":"The Emily Program  St. Paul Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8788-4878","authenticated-orcid":false,"given":"Manfred","family":"Fichter","sequence":"additional","affiliation":[{"name":"Roseneck Hospital for Behavioral Medicine affiliated with the University of Munich (LMU)  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0225-5125","authenticated-orcid":false,"given":"Katherine","family":"Halmi","sequence":"additional","affiliation":[{"name":"New York Presbyterian Hospital\u2010Westchester Division Weill Medical College of Cornell University  White Plains New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan S.","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Centre for Addiction and Mental Health, Department of Psychiatry Institute of Medical Science, University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly L.","family":"Klump","sequence":"additional","affiliation":[{"name":"Department of Psychology Michigan State University  East Lansing Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Lilenfeld","sequence":"additional","affiliation":[{"name":"Department of Psychology American School of Professional Psychology at Argosy University  Arlington Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre J.","family":"Magistretti","sequence":"additional","affiliation":[{"name":"Department of Psychiatry CHUY\/University of Lausenne  Switzerland"},{"name":"Brain Mind Institute  Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5434-6021","authenticated-orcid":false,"given":"James","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Clinical Research Neuropsychiatric Research Institute  Fargo North Dakota"},{"name":"Department of Psychiatry and Behavioral Science University of North Dakota School of Medicine and Health Sciences  Fargo North Dakota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas J.","family":"Schork","sequence":"additional","affiliation":[{"name":"Department of Quantitative Medicine The Translational Genomics Research Institute  Phoenix Arizona"},{"name":"Human Biology The J. Craig Venter Institute  La Jolla California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9134-317X","authenticated-orcid":false,"given":"Michael","family":"Strober","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of California Los Angeles  Los Angeles California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura M.","family":"Thornton","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of North Carolina at Chapel Hill  Chapel Hill North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Treasure","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience King's College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6833-3264","authenticated-orcid":false,"given":"Blake","family":"Woodside","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Toronto  Toronto Ontario Canada"},{"name":"Program for Eating Disorders Toronto General Hospital  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4478-4906","authenticated-orcid":false,"given":"Walter H.","family":"Kaye","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of California at San Diego  San Diego California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6542-5147","authenticated-orcid":false,"given":"Pamela K.","family":"Keel","sequence":"additional","affiliation":[{"name":"Department of Psychology Florida State University  Tallahassee Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2017.07.012"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2009.11.001"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X(199503)17:2<147::AID-EAT2260170207>3.0.CO;2-X"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-9338(01)00570-3"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpsp.12103"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X(200009)28:2<139::AID-EAT2>3.0.CO;2-G"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2005.04.012"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1993.01820240059008"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12378-1"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03325050"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01172967"},{"key":"e_1_2_7_14_1","volume-title":"Eating disorder inventory\u20102 professional manual","author":"Garner D. M.","year":"1990"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X(198321)2:2<15::AID-EAT2260020203>3.0.CO;2-6"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/10705519909540118"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20605"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(99)00240-1"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291704002442"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.104.1.140"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699930902985845"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22739"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20029"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X(199511)18:3<237::AID-EAT2260180305>3.0.CO;2-1"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20120"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.10032"}],"container-title":["International Journal of Eating Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Feat.23008","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.23008","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/eat.23008","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/am-pdf\/10.1002\/eat.23008","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.23008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T23:28:44Z","timestamp":1694734124000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/eat.23008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,12]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1002\/eat.23008"],"URL":"https:\/\/doi.org\/10.1002\/eat.23008","archive":["Portico"],"relation":{},"ISSN":["0276-3478","1098-108X"],"issn-type":[{"value":"0276-3478","type":"print"},{"value":"1098-108X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,12]]},"assertion":[{"value":"2018-07-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}