{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T17:36:19Z","timestamp":1772127379397,"version":"3.50.1"},"reference-count":51,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,17]],"date-time":"2019-01-17T00:00:00Z","timestamp":1547683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["BR 48\/1\u20101"],"award-info":[{"award-number":["BR 48\/1\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Patients with anorexia nervosa (AN) often show difficulties in the perception, expression, and regulation of emotions and a strong avoidance of aversive feelings. According to psychobiological models, dietary restraint and accompanying weight loss may serve as a maladaptive mechanism of emotion regulation by attenuating aversive emotional states in AN, thereby contributing to the maintenance of the disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Twenty\u2010seven women with AN and 26 age\u2010matched healthy women were shown short film\u2010clips to elicit fear, sadness, amusement, and neutral emotional states. Eyeblink startle response was measured by electromyography in reaction to startle\u2010eliciting acoustic stimuli presented 12 times binaurally during each film\u2010clip.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>As compared to healthy controls, patients with AN showed a blunted startle response to the fear\u2010 but not to the sadness\u2010eliciting stimulus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The findings support the assumption that underweight is associated with attenuated emotional reactivity to fear\u2010eliciting material in AN. This is in line with the hypothesis that starvation and low body weight constitute a maladaptive mechanism of emotion regulation in AN, contributing to the maintenance of the disorder.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23022","type":"journal-article","created":{"date-parts":[[2019,1,17]],"date-time":"2019-01-17T19:12:32Z","timestamp":1547752352000},"page":"270-277","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Blunted emotion\u2010modulated startle reflex in anorexia nervosa"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2544-7610","authenticated-orcid":false,"given":"Timo","family":"Brockmeyer","sequence":"first","affiliation":[{"name":"Department of General Internal Medicine and Psychosomatics, Center for Psychosocial Medicine Heidelberg University Hospital  Heidelberg Germany"},{"name":"Department of Psychosomatic Medicine and Psychotherapy, Medical Faculty Heinrich\u2010Heine\u2010University  Duesseldorf Germany"},{"name":"Department of Clinical Psychology and Psychotherapy Institute of Psychology, University of Goettingen  Goettingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Pellegrino","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine and Psychosomatics, Center for Psychosocial Medicine Heidelberg University Hospital  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Maier","sequence":"additional","affiliation":[{"name":"Faculty of Informatics Heilbronn University  Heilbronn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah M.","family":"M\u00fcnch","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine and Psychosomatics, Center for Psychosocial Medicine Heidelberg University Hospital  Heidelberg Germany"},{"name":"Department of Clinical Psychology and Psychotherapy Eberhard Karls University T\u00fcbingen  T\u00fcbingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine J.","family":"Harmer","sequence":"additional","affiliation":[{"name":"University Department of Psychiatry University of Oxford  Oxford United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Walther","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine and Psychosomatics, Center for Psychosocial Medicine Heidelberg University Hospital  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Herzog","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine and Psychosomatics, Center for Psychosocial Medicine Heidelberg University Hospital  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans\u2010Christoph","family":"Friederich","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine and Psychosomatics, Center for Psychosocial Medicine Heidelberg University Hospital  Heidelberg Germany"},{"name":"Department of Psychosomatic Medicine and Psychotherapy, Medical Faculty Heinrich\u2010Heine\u2010University  Duesseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(97)00331-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1479-x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2012.08.007"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.2005.00271.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.07.009"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2013.06.024"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2011.09.003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2014.09.011"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20852"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.1157"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.02.015"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1997.tb48289.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2502"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000453582"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291706008129"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8295.1994.tb02508.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(03)00202-5"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699939508408966"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1401-6"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2010.04.037"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.974"},{"key":"e_1_2_7_23_1","first-page":"208","volume-title":"Obesity","author":"Herman C. P.","year":"1980"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699930541000084"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1994.tb02349.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8760(98)00063-4"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2007.11.037"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.10135"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(98)00098-7"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002130000505"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.1.134"},{"key":"e_1_2_7_32_1","volume-title":"The startle pattern","author":"Landis C.","year":"1939"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1037\/0003-066X.50.5.372"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(98)00275-3"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2017.07.010"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00998191"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20276"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2015.04.005"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699939308409183"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2016.02.014"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.12160"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2010.08.004"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-3057(95)00110-I"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-108X(199903)25:2<177::AID-EAT7>3.0.CO;2-D"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291709990377"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.2190\/PM.44.1.d"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2181"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.97.4.487"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0992(199607)26:4<557::AID-EJSP769>3.0.CO;2-4"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20730"},{"key":"e_1_2_7_51_1","volume-title":"Structural clinical interview for DSM\u2010IV (SKID\u2010I and SKID\u2010II) [in German]","author":"Wittchen H. U.","year":"1997"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2004.11.006"}],"container-title":["International Journal of Eating Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Feat.23022","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.23022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T12:24:28Z","timestamp":1694694268000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/eat.23022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,17]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1002\/eat.23022"],"URL":"https:\/\/doi.org\/10.1002\/eat.23022","archive":["Portico"],"relation":{},"ISSN":["0276-3478","1098-108X"],"issn-type":[{"value":"0276-3478","type":"print"},{"value":"1098-108X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,17]]},"assertion":[{"value":"2018-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}