{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T16:49:52Z","timestamp":1776962992179,"version":"3.51.4"},"reference-count":69,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T00:00:00Z","timestamp":1571184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) are common disorders in childhood and are frequently accompanied by comorbid psychiatric disorders. Despite a high association between urinary and fecal incontinence with psychiatric and neurodevelopmental disorders, research on comorbidity between incontinence and anorexia nervosa (AN) remains scarce. Yet, it is well known that somatic consequences of AN include metabolic and gastrointestinal disorders. The study sought to assess the prevalence of incontinence and constipation in children and adolescents with AN and to examine associations of these two symptoms with body weight at admission and with BMI changes during inpatient treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data collected between 2015 and 2017 by a multicenter German web\u2010based registry for AN were analyzed. Three hundred and forty\u2010eight patients with AN (96.3% female, mean age = 15.1\u2009\u00b1\u20091.8\u2009years) were assessed regarding AN subtype, psychiatric comorbidity, body weight, incontinence, and constipation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 27.6% of patients had constipation, 1.8% had NE and 1.8% DUI. Prevalence of constipation did not significantly differ between AN subtypes. Constipation did not lead to any significant differences in weight\/BMI changes during inpatient treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>This is the largest study of incontinence and constipation in patients with AN, so far. Our results indicate that constipation is highly prevalent in adolescent patients with AN and reflects a clinically relevant condition. Despite, patients with AN do not have an increased prevalence of incontinence compared with the general population. Future studies should include medical examinations like ultrasound and physical examination of the lower abdomen to evaluate the severity of constipation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23182","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T21:40:12Z","timestamp":1571262012000},"page":"219-228","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Incontinence and constipation in adolescent patients with anorexia nervosa\u2014Results of a multicenter study from a German web\u2010based registry for children and adolescents with anorexia nervosa"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4582-3820","authenticated-orcid":false,"given":"Hannah K.","family":"Mattheus","sequence":"first","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Saarland University Hospital  Homburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catharina","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Saarland University Hospital  Homburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy Philipps University Marburg and University Hospital Marburg  Marburg Germany"},{"name":"Center for Mind, Brain and Behavior (CMBB) Philipps\u2010University Marburg  Marburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8450-3323","authenticated-orcid":false,"given":"Katharina","family":"B\u00fchren","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University Hospital, RWTH Aachen  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph U.","family":"Correll","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, and Berlin Institute of Health  Berlin Germany"},{"name":"Department of Psychiatry and Molecular Medicine Hofstra Northwell School of Medicine  Hempstead New York"},{"name":"Department of Psychiatry, The Zucker Hillside Hospital Northwell Health  Glen Oaks New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin M.","family":"Egberts","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University Hospital W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Ehrlich","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Faculty of Medicine Technische Universitaet Dresden  Dresden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Fleischhaker","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry and Psychotherapy University Medical Center Freiburg  Freiburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"F\u00f6cker","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics University Hospital Essen, University of Duisburg\u2010Essen  Duisburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Freia","family":"Hahn","sequence":"additional","affiliation":[{"name":"Department of Child an Adolescent Psychiatry Psychosomatics and Psychotherapy, LVR \u2013 Hospital Viersen  Viersen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Hebebrand","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics University Hospital Essen, University of Duisburg\u2010Essen  Duisburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beate","family":"Herpertz\u2010Dahlmann","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University Hospital, RWTH Aachen  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Jaite","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, and Berlin Institute of Health  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekkehart","family":"Jenetzky","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry University Medicine of the Johannes Gutenberg\u2010University  Mainz Germany"},{"name":"Faculty of Health, School of Medicine Witten\/Herdecke University  Witten Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Kaess","sequence":"additional","affiliation":[{"name":"Clinic of Child and Adolescent Psychiatry, Center for Psychosocial Medicine University Hospital Heidelberg  Heidelberg Germany"},{"name":"University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Legenbauer PhD","sequence":"additional","affiliation":[{"name":"LWL University Hospital Hamm for Child and Adolescent Psychiatry, Ruhr University Bochum  Bochum Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens P.","family":"Pfeiffer PhD","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy Philipps University Marburg and University Hospital Marburg  Marburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias J.","family":"Renner MD","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University Hospital T\u00fcbingen  T\u00fcbingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veit","family":"Roessner","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Faculty of Medicine Technische Universitaet Dresden  Dresden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Schulze","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry\/Psychotherapy University Hospital, University of Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Sinzig","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy, LVR\u2010Klinik Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ida","family":"Wessing","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy, University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"von Gontard","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Saarland University Hospital  Homburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,16]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Adrbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF). (2018). S3\u2010Leitlinie: Diagnostik und Therapie der Essst\u00f6rungen. May 31 2018. Retrieved fromhttps:\/\/www.awmf.org\/leitlinien\/detail\/ll\/051-026.html"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2017.03.033"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22751"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001394"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedp.2017.01.004"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.22038\/ijp.2016.7703"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20829"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520510015836"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1024\/1422-4917\/a000544"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22532"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05452.x"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.4065\/75.10.1015"},{"key":"e_1_2_11_14_1","first-page":"1879","article-title":"Colonic and anorectal function in constipated patients with anorexia nervosa","volume":"92","author":"Chun A. B.","year":"1997","journal-title":"American Journal of Gastroenterology"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.67.3.340"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12820"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2010.03.003"},{"key":"e_1_2_11_18_1","first-page":"417","article-title":"Elimination disorders and anxious\u2010depressed symptoms in preschool children: A population\u2010based study","volume":"23","author":"Equit M.","year":"2014","journal-title":"European Child & Adolescent Psychiatry"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2006.05.002"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3758\/BF03193146"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1024\/1422-4917\/a000545"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/0036552031000212"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.05.165"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568007033338715"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1024\/1422-4917\/a000579"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62411-3"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-017-0945-7"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2019.174"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.015"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40519-013-0020-4"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199806000-00014"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(91)90083-W"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20822"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000000247"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20260"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200112000-00014"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001120170107"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2007.01212.x"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep26752"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.12740\/PP\/65274"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20924"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40337-015-0040-8"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2010.12.010"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.03.180"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2015.02.009"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22462"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.02.025"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986712803530476"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.2165\/00148581-200709010-00004"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2011.17.1.35"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1037\/pha0000194"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.2165\/11898640-000000000-00000"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199902000-00015"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20706"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-015-0611-x"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2009.07.005"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1097\/YIC.0000000000000276"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-013-1068-x"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-012-0282-y"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40337-017-0154-2"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1636555"},{"key":"e_1_2_11_63_1","doi-asserted-by":"crossref","DOI":"10.17433\/978-3-17-026627-8","volume-title":"Leitfaden Enkopresis","author":"Gontard A.","year":"2010"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22997"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.07.030"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24016"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(90)91070-M"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2015.06.031"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.12740\/PP\/35482"},{"key":"e_1_2_11_70_1","volume-title":"The ICD\u201010 classification of mental and behavioural disorders: Clinical descriptions and diagnostic guidelines","author":"World Health Organization","year":"1992"}],"container-title":["International Journal of Eating Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Feat.23182","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.23182","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/eat.23182","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.23182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T07:21:28Z","timestamp":1692688888000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/eat.23182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,16]]},"references-count":69,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1002\/eat.23182"],"URL":"https:\/\/doi.org\/10.1002\/eat.23182","archive":["Portico"],"relation":{},"ISSN":["0276-3478","1098-108X"],"issn-type":[{"value":"0276-3478","type":"print"},{"value":"1098-108X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,16]]},"assertion":[{"value":"2019-04-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}