{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T09:29:53Z","timestamp":1774949393693,"version":"3.50.1"},"reference-count":51,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T00:00:00Z","timestamp":1585267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R34MH118353"],"award-info":[{"award-number":["R34MH118353"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Outcomes from cognitive behavioral therapy (CBT) for bulimia nervosa (BN) and binge\u2010eating disorder (BED) are suboptimal. One potential explanation is that CBT fails to adequately target inhibitory control (i.e., the ability to withhold an automatic response), which is a key maintenance factor for binge eating. Computerized inhibitory control training (ICT) is a promising method for improving inhibitory control but is relatively untested in BN\/BED. The present study will evaluate a computer\u2010based ICT as an adjunct to CBT for BN\/BED. Participants with BN (<jats:italic>n<\/jats:italic> = 30) or BED (<jats:italic>n<\/jats:italic> = 30) will be randomized to 12\u2009weeks of either CBT\u2009+\u2009ICT or CBT\u2009+\u2009a sham training. Trainings will be completed daily for 4\u2009weeks and weekly for 8\u2009weeks. Primary aims include the following: (a) confirm target engagement (evaluate whether ICT improves inhibitory control), (b) test target validation (evaluate whether improvements in inhibitory control are associated with improvements in binge eating), and (c) evaluate the incremental efficacy of ICT on binge eating. Secondary aims include the following: (a) evaluate ICT feasibility and acceptability and (b) assess the moderating effects of approach tendencies on highly palatable food, dietary restraint, and diagnosis. Data will be used to shape a fully powered clinical trial designed to assess efficacy and dose\u2013response effects of ICT for BN\/BED.<\/jats:p>","DOI":"10.1002\/eat.23225","type":"journal-article","created":{"date-parts":[[2020,3,28]],"date-time":"2020-03-28T06:02:26Z","timestamp":1585375346000},"page":"1007-1013","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The project REBOOT protocol: Evaluating a personalized inhibitory control training as an adjunct to cognitive behavioral therapy for bulimia nervosa and binge\u2010eating disorder"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4666-588X","authenticated-orcid":false,"given":"Stephanie M.","family":"Manasse","sequence":"first","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth W.","family":"Lampe","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania"},{"name":"Department of Psychology Drexel University  Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay","family":"Gillikin","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Payne\u2010Reichert","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Psychology Drexel University  Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrienne S.","family":"Juarascio","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania"},{"name":"Department of Psychology Drexel University  Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan M.","family":"Forman","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania"},{"name":"Department of Psychology Drexel University  Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/17437199.2015.1051078"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1026\/\/0949-3946.48.2.145"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3564-13.2014"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpra.2016.08.003"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20370"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2009.107"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1037\/xge0000236"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X(198701)6:1<1::AID-EAT2260060102>3.0.CO;2-9"},{"key":"e_1_2_6_10_1","unstructured":"Davis F. 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