{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:54:44Z","timestamp":1783558484274,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T00:00:00Z","timestamp":1582502400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Improved treatment outcome in family\u2010based treatment (FBT) for anorexia nervosa (AN) is predicted by weight gain occurring early in the course of treatment (i.e., about 4 lbs by week 4). Although prior work suggests that early weight gain in higher levels of care (e.g., partial hospitalization programs [PHP]) predicts weight restoration at discharge, no study has examined the specific rate of gain within FBT\u2010informed PHP programs that best predicts treatment response.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This study examined rate of weight gain in pounds and percent expected body weight (EBW) that predicts positive outcome in 70 patients (<jats:italic>M<\/jats:italic> age = 15.49\u2009years, SD = 2.56) with AN who were enrolled in a family\u2010based PHP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Receiver operator characteristic analyses demonstrated that changes in %EBW during weeks 2\u20135 were more useful than changes in weight in predicting positive outcome. Gaining at least 8.9 pounds or over 8% of EBW in the first 4\u2009weeks of treatment significantly predicted positive outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Findings suggest that positive outcome in an FBT\u2010informed PHP is predicted by rapid weight gain in the initial weeks of treatment. Research is needed to identify specific family and patient characteristics that facilitate weight gain and to develop corresponding interventions to improve outcome.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23248","type":"journal-article","created":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T19:04:50Z","timestamp":1582571090000},"page":"606-610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Early weight gain predicts treatment response in adolescents with anorexia nervosa enrolled in a family\u2010based partial hospitalization program"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8179-7741","authenticated-orcid":false,"given":"Jessica L.","family":"Van Huysse","sequence":"first","affiliation":[{"name":"Department of Psychiatry University of Michigan  Ann Arbor Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kellsey","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Michigan  Ann Arbor Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Mammel","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Michigan  Ann Arbor Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Prohaska","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Michigan  Ann Arbor Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0423-7403","authenticated-orcid":false,"given":"Renee D.","family":"Rienecke","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Michigan  Ann Arbor Michigan"},{"name":"Department of Pediatrics Medical University of South Carolina  Charleston South Carolina"},{"name":"Department of Psychiatry and Behavioral Sciences Medical University of South Carolina  Charleston South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/10640266.2013.779188"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20931"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X(198701)6:1<1::AID-EAT2260060102>3.0.CO;2-9"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20764"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2449"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1467-6427.12055"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22221"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2016.05.007"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2011.11.003"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/10640266.2017.1388664"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20328"},{"key":"e_1_2_7_13_1","volume-title":"Treatment manual for anorexia nervosa: A family\u2010based approach","author":"Lock J.","year":"2012"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2010.128"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22414"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22679"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/10640266.2018.1528085"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2495"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10979-005-6832-7"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2577"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-4080"},{"key":"e_1_2_7_22_1","first-page":"1","article-title":"Changes in meal\u2010related anxiety predict treatment outcomes in an intensive family\u2010based treatment program for adolescents with anorexia nervosa","author":"Smith K. 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