{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T22:34:44Z","timestamp":1768430084416,"version":"3.49.0"},"reference-count":67,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,4,25]],"date-time":"2020-04-25T00:00:00Z","timestamp":1587772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["GR18136"],"award-info":[{"award-number":["GR18136"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with eating disorders (ED) are very sensitive and responsive to psychosocial stress. Stress response includes changes in immune cell distribution and may be modulated by the capability to cope with stressors. Thus, the present study sought to analyze the association between coping strategies and immune response (natural killer [NK] cell redistribution following psychosocial stress) in patients with anorexia nervosa (AN) and bulimia nervosa (BN) and healthy controls (HC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Twenty\u2010four AN patients, 29 BN patients, and 58 HC were studied. A multidimensional assessment tool, the COPE Inventory, was used to assess coping strategies. The number of NK cells was quantified in peripheral blood before and after the application of the Trier Social Stress Test (TSST). Potentially mediating variables, such as weight status, severity of eating pathology, depression, anxiety, and impulsivity were controlled.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The three groups differed in intensity and direction of cell redistribution: The TSST was followed in BN patients by a significant decrease in the number of NK cells, whereas HC displayed a moderate decrease and AN a clear increase. Specific correlations between coping strategies and NK cell mobilization were found, especially in BN patients (positive for \u201cplanning\u201d and negative for \u201csubstance abuse\u201d).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Recognition and subsequent modification of the dysfunctional coping strategies used by patients with ED could contribute to improving their immune status, strengthening their resilience and increasing their ability to overcome the disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23278","type":"journal-article","created":{"date-parts":[[2020,4,25]],"date-time":"2020-04-25T10:32:55Z","timestamp":1587810775000},"page":"964-971","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Coping strategies and stress\u2010induced natural killer cell redistribution in women with eating disorders"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4872-3924","authenticated-orcid":false,"given":"Francisco J.","family":"Vaz\u2010Leal","sequence":"first","affiliation":[{"name":"University Hospital\/University Hospital Network Extremadura Health Service  Badajoz Spain"},{"name":"Faculty of Medicine University of Extremadura  Badajoz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Isabel","family":"Ramos\u2010Fuentes","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Extremadura  Badajoz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Antonio","family":"Guisado\u2010Mac\u00edas","sequence":"additional","affiliation":[{"name":"University Hospital\/University Hospital Network Extremadura Health Service  Badajoz Spain"},{"name":"Faculty of Medicine University of Extremadura  Badajoz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guadalupe","family":"Esp\u00e1rrago\u2010Llorca","sequence":"additional","affiliation":[{"name":"Eating Disorders Unit, University Hospital Network Extremadura Health Service  C\u00e1ceres Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia","family":"Redondo\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Faculty of Education University of Extremadura  Badajoz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Bajo\u2010Cabello","sequence":"additional","affiliation":[{"name":"College of Nursing and Occupational Therapy University of Extremadura  C\u00e1ceres Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Rodr\u00edguez\u2010Santos","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Extremadura  Badajoz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,4,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2016.11.001"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2007.10.007"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2007.02.001"},{"key":"e_1_2_8_5_1","volume-title":"Beck depression inventory. 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