{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T22:47:18Z","timestamp":1782514038570,"version":"3.54.5"},"reference-count":54,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to compare the effectiveness of an intensive treatment based on enhanced cognitive behavioral therapy (CBT\u2010E) in adolescent and adult patients with anorexia nervosa.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 150 consecutive patients (74 adolescents and 81 adults) were admitted to a 20\u2010week intensive CBT\u2010E program (13\u2009weeks of inpatient followed by 7\u2009weeks of day\u2010hospital treatment). All patients had responded poorly to previous outpatient treatments and were assessed at admission, end of treatment (EOT), and 20\u2010 and 60\u2010week follow\u2010ups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>About 70% of eligible patients began the program, and more than 85% completed it. Body mass index (BMI) in adults and BMI\u2010for\u2010age percentile in adolescents improved significantly from baseline to EOT, remained stable until 20\u2010week follow\u2010up, and slightly decreased from 20\u2010week follow\u2010up to 60\u2010week follow\u2010up, while remaining in the lower normal range. Eating disorder psychopathology, general psychopathology, and clinical impairment scores decreased significantly at EOT and showed only a slight increase from EOT to follow\u2010ups. No difference was found between adolescent and adult patients in treatment acceptance, dropout, or any outcome measure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>These findings indicate that intensive CBT\u2010E seems to be an effective treatment for severely ill adolescent and adult patients with anorexia nervosa.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23337","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T08:14:27Z","timestamp":1595319267000},"page":"1428-1438","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Effectiveness of intensive cognitive behavioral therapy in adolescents and adults with anorexia nervosa"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9796-3721","authenticated-orcid":false,"given":"Riccardo","family":"Dalle Grave","sequence":"first","affiliation":[{"name":"Department of Eating and Weight Disorders Villa Garda Hospital  Garda (VR) Veneto Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maddalena","family":"Conti","sequence":"additional","affiliation":[{"name":"Department of Eating and Weight Disorders Villa Garda Hospital  Garda (VR) Veneto Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4028-1877","authenticated-orcid":false,"given":"Simona","family":"Calugi","sequence":"additional","affiliation":[{"name":"Department of Eating and Weight Disorders Villa Garda Hospital  Garda (VR) Veneto Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2009.11.001"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10503307.2010.547530"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2008.06.012"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22715"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291717001349"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2016.11.006"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40519-016-0276-6"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40519-018-0477-2"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291703001168"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20591"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39238.399444.55"},{"key":"e_1_2_6_14_1","first-page":"221","volume-title":"Cognitive behavior therapy and eating disorders","author":"Cooper Z.","year":"2008"},{"key":"e_1_2_6_15_1","first-page":"248","volume-title":"Handbook of treatment for eating disorders","author":"Crisp A.","year":"1997"},{"key":"e_1_2_6_16_1","volume-title":"Intensive cognitive behavior therapy for eating disorders","author":"Dalle Grave R.","year":"2012"},{"key":"e_1_2_6_17_1","volume-title":"Multistep cognitive behavioral therapy for eating disorders: Theory, practice, and clinical cases","author":"Dalle Grave R.","year":"2013"},{"key":"e_1_2_6_18_1","volume-title":"Cognitive behavior therapy for adolescents with eating disorders","author":"Dalle Grave R.","year":"2020"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000350058"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2012.09.008"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2014.00014"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23122"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8260.1993.tb01045.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700048017"},{"key":"e_1_2_6_25_1","volume-title":"Cognitive behavior therapy and eating disorders","author":"Fairburn C. 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