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Mindfulness and acceptance\u2010based treatments (MABTs) integrate behavioral treatment with psychological strategies designed to enhance self\u2010regulation, yet little is known about how and for whom they are effective. The present study will utilize the multiphase optimization strategy to identify which of four MABT components (mindful awareness, distress tolerance, emotion modulation, values\u2010based decision making) to include in a fully powered clinical trial. Participants (<jats:italic>n<\/jats:italic> = 256) will be randomized to 16 sessions in one of 16 conditions, each a different combination of MABT components being included or excluded from a base behavioral treatment. Our primary aim is to evaluate each component's independent efficacy on disordered eating symptoms. Our secondary aims are to confirm each component's target engagement (i.e., whether each component improves the targeted variable and outcomes), and test that each component's efficacy is moderated by baseline weaknesses in the same component (e.g., that participants with poor distress tolerance at baseline benefit most from the distress tolerance component). Our exploratory aim is to quantify the component interaction effects.<\/jats:p>","DOI":"10.1002\/eat.23426","type":"journal-article","created":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T17:29:23Z","timestamp":1607362163000},"page":"451-458","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The project <scp>COMPASS<\/scp> protocol: Optimizing mindfulness and acceptance\u2010based behavioral treatment for binge\u2010eating spectrum disorders"],"prefix":"10.1002","volume":"54","author":[{"given":"Adrienne S.","family":"Juarascio","sequence":"first","affiliation":[{"name":"Department of Psychology Drexel University  Philadelphia Pennsylvania USA"},{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9964-2331","authenticated-orcid":false,"given":"Christina R.","family":"Felonis","sequence":"additional","affiliation":[{"name":"Department of Psychology Drexel University  Philadelphia Pennsylvania USA"},{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie M.","family":"Manasse","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paakhi","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Boyajian","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan M.","family":"Forman","sequence":"additional","affiliation":[{"name":"Department of Psychology Drexel University  Philadelphia Pennsylvania USA"},{"name":"Center for Weight, Eating, and Lifestyle Science Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Psychology Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1037\/ccp0000073"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12671-015-0419-2"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073191105283504"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(94)90005-1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22204"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2673"},{"key":"e_1_2_8_8_1","volume-title":"Losing control: How and why people fail at self\u2010regulation","author":"Baumeister R. 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