{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:53:53Z","timestamp":1747148033077,"version":"3.40.5"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T00:00:00Z","timestamp":1616976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Low bone mineral density (BMD) in anorexia nervosa (AN) leads to increased risk of fractures. Debate exists whether to medicinally treat young patients with AN based on abnormal dual\u2010energy x\u2010ray absorptiometry (DXA) scores or to weight restore and reassess when older. Trabecular bone score (TBS), a technology measuring bone quality, is used in conjunction with DXA. This report explores the potential additional value of TBS, in adults with severe AN, to augment the DXA diagnostic information.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Seventy\u2010one DXA scans were reanalyzed to obtain TBS results from patients (mean age: 36.3\u2009years). Differences in laboratory, anthropometric values and concomitant DXA measurements in relation to TBS results are reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For the cohort, mean body mass index (BMI) was 13.6 kg\/m<jats:sup>2<\/jats:sup> (<jats:italic>SD<\/jats:italic>: 2.1). The vast majority of patients had normal TBS with a mean of 1.395 (<jats:italic>SD<\/jats:italic>: 0.08) but, most patients (69%) had abnormal average DXA BMD Z\u2010scores of \u22122.2 (<jats:italic>SD<\/jats:italic>: 1.2). The patients who also demonstrated degraded bone quality on TBS had significantly lower percent ideal body weight and elevated alkaline phosphatase compared to patients with normal TBS (<jats:italic>p<\/jats:italic>'s\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Low BMD treatment decisions in AN may be optimized by considering both DXA and TBS results.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23506","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T08:49:10Z","timestamp":1617007750000},"page":"903-907","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Bone quality assessed by trabecular bone score in severe anorexia nervosa: A brief report"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7587-8948","authenticated-orcid":false,"given":"Ashlie","family":"Watters","sequence":"first","affiliation":[{"name":"ACUTE at Denver Health  Denver Colorado USA"},{"name":"Department of Medicine University of Colorado School of Medicine  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Fielding","sequence":"additional","affiliation":[{"name":"Department of Radiology Denver Health  Denver Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9598-6428","authenticated-orcid":false,"given":"Philip S.","family":"Mehler","sequence":"additional","affiliation":[{"name":"ACUTE at Denver Health  Denver Colorado USA"},{"name":"Department of Medicine University of Colorado School of Medicine  Aurora Colorado USA"},{"name":"Eating Recovery Center  Denver Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,29]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"2019 ISCD Official Positions\u2010Adult. 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