{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T22:14:19Z","timestamp":1788387259865,"version":"build-2803163510"},"reference-count":69,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T00:00:00Z","timestamp":1620086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["ZIA\u2010HD00641"],"award-info":[{"award-number":["ZIA\u2010HD00641"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Among youth with overweight, food cravings (FC) are associated with loss\u2010of\u2010control (LOC)\u2010eating, but the impact of sex\u2010associated biological characteristics on this relationship is unknown. We examined whether sex and gonadal hormone concentrations moderated the relationships between FC and LOC\u2010eating severity among healthy boys and girls across the weight strata in natural and laboratory environments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Using ecological momentary assessment (EMA), FC, and LOC\u2010eating severity were reported 3\u20135 times a day for 2\u2009weeks. In the laboratory, participants reported FC, consumed lunch from a buffet test meal designed to simulate LOC\u2010eating, and rated LOC\u2010eating severity during the meal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty\u2010seven youth (13.0\u2009\u00b1\u20092.7\u2009years, 58.6% female, 32.2% with overweight\/obesity) participated. EMA measured general and momentary FC were positively associated with LOC\u2010eating severity (\n                      <jats:italic>ps<\/jats:italic>\n                      \u2009&lt;\u2009.01), with no differences by sex (\n                      <jats:italic>ps<\/jats:italic>\n                      \u00a0=\u00a0.21\u2013.93). Estradiol and progesterone significantly moderated the relationships between FC and LOC\u2010eating such that general FC and LOC\u2010eating severity were only positively associated among girls with greater (vs. lower) estradiol (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.01), and momentary FC and LOC\u2010eating severity were only positively associated among girls with greater (vs. lower) progesterone (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.01). Boys' testosterone did not significantly moderate the associations between FC and LOC\u2010eating severity (\n                      <jats:italic>ps<\/jats:italic>\n                      \u00a0=\u00a0.36\u2013.97). At the test meal, pre\u2010meal FC were positively related to LOC\u2010eating severity (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.01), without sex or hormonal moderation (\n                      <jats:italic>ps<\/jats:italic>\n                      \u00a0=\u00a0.20\u2013.64).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>FC were related to LOC\u2010eating severity in boys and girls. In the natural environment, gonadal hormones moderated this relationship in girls, but not boys. The mechanisms through which gonadal hormones might affect the relationship between FC and LOC\u2010eating warrant investigation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/eat.23530","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T06:33:31Z","timestamp":1620110011000},"page":"1426-1437","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Food cravings and loss\u2010of\u2010control eating in youth: Associations with gonadal hormone concentrations"],"prefix":"10.1002","volume":"54","author":[{"given":"Megan N.","family":"Parker","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Psychology Uniformed Services University of the Health Sciences (USU)  Bethesda Maryland USA"},{"name":"Section on Growth and Obesity, Division of Intramural Research Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National 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