{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:14:38Z","timestamp":1791872078197,"version":"4.3.4"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate serum uric acid (UA) levels in patients with extreme forms of eating disorders, at admission and discharge, following weeks of nutritional rehabilitation and weight restoration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This observational study enrolled 160 patients diagnosed with anorexia nervosa restricting subtype (AN\u2010R), AN binge\u2010purge subtype (AN\u2010BP), or avoidant restrictive food intake disorder (ARFID). Serum UA levels were drawn on admission and discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most of the cohorts were admitted with serum UA levels on the lower end of normal. Mean serum uric level for women was 4.3\u00a0mg\/dl (<jats:italic>SD<\/jats:italic>: 2.3). Patients diagnosed with AN\u2010BP had significantly higher UA levels on admission compared to patients with AN\u2010R and ARFID; <jats:italic>p<\/jats:italic>\u00a0&lt;\u2009.0001, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u20090.13. High UA levels positively correlated with purging and admission serum blood urea nitrogen (<jats:italic>r<\/jats:italic>\u00a0=\u2009.5, <jats:italic>p<\/jats:italic>\u00a0=\u2009.009).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Serum UA levels tended to be in the low\u2010normal range in most patients with severe AN\u2010R, but not in AN\u2010BP. However, levels did increase with nutritional intake and weight gain. There may be clinical value in checking UA levels on admission for patients with eating disorders.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23649","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T12:15:03Z","timestamp":1638360903000},"page":"141-144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Uric acid levels in adult patients with severe eating disorders"],"prefix":"10.1002","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7587-8948","authenticated-orcid":false,"given":"Ashlie","family":"Watters","sequence":"first","affiliation":[{"name":"ACUTE Center for Eating Disorders at Denver Health  Denver Colorado USA"},{"name":"Department of Medicine University of Colorado School of Medicine  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard 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