{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:27:19Z","timestamp":1780471639662,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T00:00:00Z","timestamp":1658361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["K23 MH126201"],"award-info":[{"award-number":["K23 MH126201"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01\u2010MH\u2010079978"],"award-info":[{"award-number":["R01\u2010MH\u2010079978"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01\u2010MH\u2010079979"],"award-info":[{"award-number":["R01\u2010MH\u2010079979"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Data suggest that obsessive\u2013compulsive (OC) symptoms are commonly observed in adolescents with eating disorders and predict poorer treatment response. Further, emerging data among adults suggest that changes in OC symptoms relate to changes in eating disorder symptoms across treatment. Given evidence that early invention decreases risk for protracted illness, evaluating processes that may relate to treatment response will be useful in increasing the effectiveness of existing interventions. Therefore, the current investigation explored changes in general and eating disorder\u2010specific OC symptoms throughout family\u2010based treatment (FBT) and cognitive behavioral therapy (CBT) for bulimia nervosa (BN), as well as associations among these changes and eating disorder outcomes at follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Participants (<jats:italic>N<\/jats:italic>\u00a0=\u00a0110) received 18 sessions of FBT or CBT and completed measurements of general and eating disorder\u2010specific OC symptoms at baseline, end\u2010of\u2010treatment, and 6\u2010 and 12\u2010month follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Multilevel models indicated that across both treatments, there was no change in general OC symptoms, whereas all eating disorder\u2010related OC symptoms decreased over treatment and follow\u2010up. Exploratory analyses indicated that lower severity in discharge eating\u2010disorder\u2010specific OC symptoms contributed to lower eating pathology at follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Together, findings support the efficacy of both FBT and CBT in helping to reduce eating disorder\u2010specific OC symptoms and suggest that adjunctive intervention may be required for ameliorating general OC symptoms in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Public significance<\/jats:title><jats:p>BN is associated with significant increases in mortality and societal cost, and there is a pressing need for innovations within available treatments for young people with this disorder. In the current study, we explore the extent to which existing evidence\u2010based treatments for adolescent BN are effective in targeting obsessive\u2013compulsive symptoms, a known predictor of treatment response and common co\u2010morbidity in this population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23782","type":"journal-article","created":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T10:44:07Z","timestamp":1658400247000},"page":"1342-1351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Characterizing changes in <scp>obsessive\u2013compulsive<\/scp> symptoms over the course of treatment for adolescent bulimia nervosa"],"prefix":"10.1002","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9269-0747","authenticated-orcid":false,"given":"Erin E.","family":"Reilly","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8861-8547","authenticated-orcid":false,"given":"Sasha","family":"Gorrell","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9254-1992","authenticated-orcid":false,"given":"Leigh","family":"Brosof","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences University of California  San Francisco California USA"},{"name":"Department of Psychological and Brain Sciences University of Louisville  Louisville Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5169-1484","authenticated-orcid":false,"given":"James","family":"Lock","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Stanford University School of Medicine  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7293-9496","authenticated-orcid":false,"given":"Daniel","family":"Le Grange","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences University of California  San Francisco California USA"},{"name":"Department of Psychiatry and Behavioral Neuroscience The University of Chicago  Chicago Illinois (Emeritus) USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7894(05)80054-1"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2014.1025"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2009.08.001"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.2.242"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsp.2009.10.001"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22023"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20931"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1207\/S15328007SEM0803_5"},{"key":"e_1_2_10_11_1","volume-title":"Cognitive behavior therapy and eating disorders","author":"Fairburn C. 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