{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:16:31Z","timestamp":1777932991432,"version":"3.51.4"},"reference-count":57,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T00:00:00Z","timestamp":1660608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R34\u2010MH123589"],"award-info":[{"award-number":["R34\u2010MH123589"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Although family\u2010based treatment (FBT) is considered a first\u2010line treatment for adolescent anorexia nervosa (AN), it is underutilized in community settings and is unavailable to many families for a multitude of practical reasons (e.g., costs of treatment, transportation constraints). Adapting FBT interventions for delivery in home\u2010based and community\u2010based settings may reduce pragmatic barriers to treatment uptake and engagement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This pilot effectiveness\u2010implementation trial will assess outcomes, implementation, and mechanisms of FBT adapted for the home setting (FBT\u2010HB), delivered in the context of community\u2010based behavioral health agencies. Adolescents with AN\u2010spectrum disorders (<jats:italic>n<\/jats:italic>\u00a0=\u00a050) and their caregivers will be randomly assigned to either FBT\u2010HB or home\u2010based treatment as usual (TAU; integrated family therapy approach). Caregivers and adolescents will provide data on weight, eating, and putative treatment mechanisms, including caregiver self\u2010efficacy and adolescent eating\u2010related and weight\u2010related distress. Implementation constructs of feasibility, acceptability, and appropriateness will be measured among providers and participating families.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypotheses<\/jats:title><jats:p>We expect that FBT\u2010HB will be feasible, acceptable, and appropriate, and will outperform TAU in terms of improvements in adolescent weight and eating\u2010related psychopathology. We further expect that caregiver self\u2010efficacy and adolescent eating\u2010related and weight\u2010related distress, but not general distress, will show greater improvements in FBT\u2010HB relative to TAU and will be associated with better adolescent weight and eating outcomes in FBT\u2010HB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Potential implications<\/jats:title><jats:p>The proposed study has clear potential to advance scientific and clinical understanding of the real\u2010world effectiveness of FBT for AN, including whether adapting it for the home setting improves its accessibility and effects on treatment outcome.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23796","type":"journal-article","created":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T09:53:49Z","timestamp":1660643629000},"page":"1627-1634","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Implementation and outcomes of home\u2010based treatments for adolescents with anorexia nervosa: Study protocol for a pilot effectiveness\u2010implementation trial"],"prefix":"10.1002","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1620-8300","authenticated-orcid":false,"given":"Andrea B.","family":"Goldschmidt","sequence":"first","affiliation":[{"name":"Department of Psychiatry University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina C.","family":"Tortolani","sequence":"additional","affiliation":[{"name":"Department of Counseling, Educational Leadership, and School Psychology Rhode Island College  Providence Rhode Island USA"},{"name":"Department of Psychiatry and Human Behavior Warren Alpert Medical School of Brown University  Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8499-8610","authenticated-orcid":false,"given":"Amy H.","family":"Egbert","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Human Behavior Warren Alpert Medical School of Brown University  Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie A.","family":"Brick","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Human Behavior Warren Alpert Medical School of Brown University  Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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