{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:26:14Z","timestamp":1792088774025,"version":"4.4.0"},"reference-count":48,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH129478"],"award-info":[{"award-number":["R01MH129478"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["F31MH131262"],"award-info":[{"award-number":["F31MH131262"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Adjunctive mobile health (mHealth) technologies offer promise for improving treatment response to enhanced cognitive\u2010behavior therapy (CBT\u2010E) among individuals with binge\u2010spectrum eating disorders, but research on the key \u201cactive\u201d components of these technologies has been very limited. The present study will use a full factorial design to (1) evaluate the optimal combination of complexity of two commonly used mHealth components (i.e., self\u2010monitoring and microinterventions) alongside CBT\u2010E and (2) test whether the optimal complexity level of these interventions is moderated by baseline self\u2010regulation. Secondary aims of the present study include evaluating target engagement associated with each level of these intervention components and quantifying the component interaction effects (i.e., partially additive, fully additive, or synergistic effects).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Two hundred and sixty\u2010four participants with binge\u2010spectrum eating disorders will be randomized to six treatment conditions determined by the combination of self\u2010monitoring condition (i.e., standard self\u2010monitoring or skills monitoring) and microinterventions condition (i.e., no microinterventions, automated microinterventions, or just\u2010in\u2010time adaptive interventions) as an augmentation to 16 sessions of CBT\u2010E. Treatment outcomes will be measured using the Eating Disorder Examination and compared by treatment condition using multilevel models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Results will clarify the \u201cactive\u201d components in mHealth interventions for binge eating.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The present study will provide critical insight into the efficacy of commonly used digital intervention components (i.e., skills monitoring and microinterventions) alongside CBT\u2010E. Furthermore, results of this study may inform personalization of digital intervention intensity based on patient profiles of self\u2010regulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Public Significance<\/jats:title><jats:p>This study will examine the relative effectiveness of commonly used components of application\u2010based interventions as an augmentation to cognitive\u2010behavioral therapy for binge eating. Findings from this study will inform the development of an optimized digital intervention for individuals with binge eating.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23864","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T10:08:17Z","timestamp":1669802897000},"page":"470-477","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Optimizing digital health technologies to improve therapeutic skill use and acquisition alongside enhanced c<scp>ognitive\u2010behavior<\/scp> therapy for b<scp>inge\u2010spectrum<\/scp> eating disorders: Protocol for a randomized controlled trial"],"prefix":"10.1002","volume":"56","author":[{"given":"Adrienne S.","family":"Juarascio","sequence":"first","affiliation":[{"name":"Department of Psychological and Brain Sciences Drexel University  Philadelphia Pennsylvania USA"},{"name":"Center for Weight, Eating, and Lifestyle Sciences Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6854-1207","authenticated-orcid":false,"given":"Emily K.","family":"Presseller","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences Drexel University  Philadelphia Pennsylvania USA"},{"name":"Center for Weight, Eating, and Lifestyle Sciences Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Trainor","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences Drexel University  Philadelphia Pennsylvania USA"},{"name":"Center for Weight, Eating, and Lifestyle Sciences Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sneha","family":"Boda","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Sciences Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4666-588X","authenticated-orcid":false,"given":"Stephanie M.","family":"Manasse","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Sciences Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paakhi","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Center for Weight, Eating, and Lifestyle Sciences Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan M.","family":"Forman","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences Drexel University  Philadelphia Pennsylvania USA"},{"name":"Center for Weight, Eating, and Lifestyle Sciences Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-016-0673-6"},{"key":"e_1_2_11_3_1","volume-title":"Exploring the adoption of smartphone technology: Literature review","author":"Aldhaban F.","year":"2012"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.1131"},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. 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