{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T16:29:42Z","timestamp":1793464182433,"version":"4.5.0"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["K08 MH120341"],"award-info":[{"award-number":["K08 MH120341"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01 MH115128\u201004S1"],"award-info":[{"award-number":["R01 MH115128\u201004S1"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R34 MH127203"],"award-info":[{"award-number":["R34 MH127203"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Relapse following acute treatment for anorexia nervosa (AN) is common. Evidence suggests cognitive\u2010behavioral therapy (CBT) may be useful in the post\u2010acute period, but few patients have access to trained providers. mHealth technologies have potential to increase access to high\u2010quality care for AN, including in the post\u2010acute period. The aim of this study is to estimate the preliminary feasibility and effectiveness of a CBT\u2010based mobile intervention plus treatment as usual (TAU), offered with and without an accompanying social networking feature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In the current pilot randomized controlled trial, women with AN who have been discharged from acute treatment in the past 2 months (<jats:italic>N<\/jats:italic>\u00a0=\u00a090) will be randomly assigned to a CBT\u2010based mobile intervention plus treatment as usual (TAU), a CBT\u2010based mobile intervention including social networking plus TAU, or TAU alone. We will examine feasibility, acceptability, and preliminary effectiveness of the three conditions in terms of reducing eating disorder psychopathology, reducing frequency of eating disorder behaviors, achieving weight maintenance, reducing depression and suicidal ideation, and reducing clinical impairment. We will examine rehospitalization and full recovery rates in an exploratory fashion. We will also examine whether the mobile intervention and social networking feature change the proposed targets and whether changes in targets are associated with benefit, as well as conduct exploratory analyses to identify within\u2010mobile intervention predictors and moderators of outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Ultimately, this research may lead to increased access to evidence\u2010based treatment for individuals with AN and prevention of the extreme negative consequences that can result from this serious disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Public Significance<\/jats:title><jats:p>Relapse after acute treatment for anorexia nervosa is common, and few patients have access to trained providers to support them following acute care. This study will pilot a coached mobile app, including a social networking component, for this population. If ultimately successful, our approach could greatly increase access to evidence\u2010based treatment for individuals with anorexia nervosa and ultimately prevent the extreme negative consequences that can result from this serious disorder.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23891","type":"journal-article","created":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T10:33:00Z","timestamp":1673087580000},"page":"654-661","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["A pilot randomized controlled trial of a cognitive\u2010behavioral therapy guided self\u2010help mobile app for the post\u2010acute treatment of anorexia nervosa: A registered report"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7064-3835","authenticated-orcid":false,"given":"Ellen E.","family":"Fitzsimmons\u2010Craft","sequence":"first","affiliation":[{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agatha A.","family":"Laboe","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"McGinnis","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Laure","family":"Firebaugh","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6006-3263","authenticated-orcid":false,"given":"Jillian","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wallendorf","sequence":"additional","affiliation":[{"name":"Division of Biostatistics Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinna","family":"Jacobi","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Psychotherapy Technische Universit\u00e4t Dresden  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1855-6328","authenticated-orcid":false,"given":"Anna M.","family":"Bardone\u2010Cone","sequence":"additional","affiliation":[{"name":"Department of Psychology and Neuroscience University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4584-4250","authenticated-orcid":false,"given":"Kathleen M.","family":"Pike","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4564-6548","authenticated-orcid":false,"given":"C. Barr","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Stanford University School of Medicine  Stanford California USA"},{"name":"Center for m<sup>2<\/sup>Health Palo Alto University  Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise E.","family":"Wilfley","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eatbeh.2014.04.003"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/16506070903318960"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eatbeh.2022.101651"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2009.11.001"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-016-1019-y"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0000000000000453"},{"key":"e_1_2_9_8_1","first-page":"315","volume-title":"Cognitive behavior therapy and eating disorders","author":"Bohn K.","year":"2008"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23218"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291717001349"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-015-0551-7"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732314524029"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22110"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2012.09.010"},{"key":"e_1_2_9_15_1","volume-title":"Cognitive behavior therapy and eating disorders","author":"Fairburn C. 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