{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:33:29Z","timestamp":1785429209067,"version":"3.56.0"},"reference-count":45,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T00:00:00Z","timestamp":1684195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010809","name":"Jascha Fonden","doi-asserted-by":"publisher","award":["2021\u20100123"],"award-info":[{"award-number":["2021\u20100123"]}],"id":[{"id":"10.13039\/100010809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Evidence linking childhood body mass index (BMI) with subsequent eating disorders is equivocal. Potential explanations include different study populations and size, and that anorexia nervosa (AN) and bulimia nervosa (BN) should be studied separately. We examined whether birthweight and childhood BMI were associated with subsequent risk of AN and BN in girls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We included 68,793 girls from the Copenhagen School Health Records Register born between 1960 and 1996 with information on birthweight and measured weights and heights obtained from school health examinations at ages 6\u201315\u2009years. Diagnoses of AN and BN were retrieved from Danish nationwide patient registers. We used Cox proportional hazards regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 355 cases of AN (median age: 19.0) and 273 cases of BN (median age: 21.8). Higher childhood BMI was linearly associated with decreasing risk of AN and increasing risk of BN at all childhood ages. At age 6, the HR for AN was 0.85 (95% CI: 0.74\u20130.97) per BMI <jats:italic>z<\/jats:italic>\u2010score and the HR for BN was 1.78 (95% CI: 1.50\u20132.11) per BMI <jats:italic>z<\/jats:italic>\u2010score. Birthweight &gt;3.75\u2009kg was associated with increased risk of BN compared to a birthweight of 3.26\u20133.75\u2009kg.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Higher BMI in girls at ages 6\u201315\u2009years was associated with decreasing risk of AN and increasing risk of BN. Premorbid BMI could be relevant for the etiology of AN and BN, and in identifying high risk individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Public significance<\/jats:title><jats:p>Eating disorders are associated with elevated mortality, especially AN. Using a cohort of Copenhagen school children, we linked information on BMI at ages 6\u201315\u2009years for 68,793 girls with nationwide patient registers. Low childhood BMI was associated with increased risk of AN, whereas high childhood BMI was associated with increased risk of BN. These findings may assist clinicians in identifying individuals at high\u2010risk of these diseases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.23986","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T05:45:12Z","timestamp":1684302312000},"page":"1614-1622","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Childhood body mass index and the subsequent risk of anorexia nervosa and bulimia nervosa among women: A large Danish population\u2010based study"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1624-9789","authenticated-orcid":false,"given":"Katja Biering","family":"Leth\u2010M\u00f8ller","sequence":"first","affiliation":[{"name":"Center for Clinical Research and Prevention Copenhagen University Hospital\u2013Bispebjerg and Frederiksberg  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5364-6073","authenticated-orcid":false,"given":"Johannes","family":"Hebebrand","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics University Hospital Essen, University of Duisburg\u2010Essen  Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7061-3767","authenticated-orcid":false,"given":"Katrine","family":"Strandberg\u2010Larsen","sequence":"additional","affiliation":[{"name":"Section of Epidemiology, Department of Public Health University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9649-6615","authenticated-orcid":false,"given":"Jennifer Lyn","family":"Baker","sequence":"additional","affiliation":[{"name":"Center for Clinical Research and Prevention Copenhagen University Hospital\u2013Bispebjerg and Frederiksberg  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4921-9604","authenticated-orcid":false,"given":"Britt Wang","family":"Jensen","sequence":"additional","affiliation":[{"name":"Center for Clinical Research and Prevention Copenhagen University Hospital\u2013Bispebjerg and Frederiksberg  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2011.74"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyn164"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31816339c6"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22584"},{"key":"e_1_2_10_7_1","volume-title":"DSM\u20105\u00ae guidebook: The essential companion to the diagnostic and statistical manual of mental disorders","author":"Black D. 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