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Students also reported on insomnia, post\u2010traumatic stress, alcohol use, and suicide risk. Before treatment, they indicated the mental health problem that they preferred to target first in treatment. Preferred treatment focus was characterized by diagnostic profile (i.e., ED\u2009+\u2009Depression, ED\u2009+\u2009Anxiety, ED\u2009+\u2009Depression\u2009+\u2009Anxiety), symptom severity, and demographics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>58% of students with ED\u2009+\u2009Anxiety, 47% of those with ED\u2009+\u2009Depression, and 27% of those with ED\u2009+\u2009Depression\u2009+\u2009Anxiety chose to target EDs first. Across diagnostic profiles, those who chose to target EDs first had more severe ED symptoms than those who chose to target anxiety or depression (<jats:italic>ps<\/jats:italic>\u2009&lt;\u2009.05). Among students with ED\u2009+\u2009Depression\u2009+\u2009Anxiety, those who chose to target EDs first had lower depression symptoms than those who chose to target depression, lower generalized anxiety than those who chose to target anxiety, and lower suicidality than those who chose to target anxiety or depression (<jats:italic>ps<\/jats:italic>\u2009&lt;\u2009.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Students with EDs and comorbid depression and\/or anxiety disorders showed variable preferred treatment focus across diagnostic profiles. Research should explore specific symptom presentations associated with preferred treatment focus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Public Significance<\/jats:title><jats:p>Findings indicate that a sizable percentage of college students with depression\/anxiety who also have EDs prefer to target EDs first in treatment, highlighting the importance of increasing availability of ED interventions to college students. Students with EDs and comorbid depression and\/or anxiety disorders showed variable preferred treatment focus across diagnostic profiles, and preference to target EDs was associated with greater ED psychopathology across diagnostic profiles.<\/jats:p><\/jats:sec>","DOI":"10.1002\/eat.24065","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T14:28:47Z","timestamp":1695911327000},"page":"2349-2357","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preferred treatment focus among college students with eating disorders and comorbid mental health problems in a digital cognitive\u2010behavioral guided self\u2010help program"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9963-7316","authenticated-orcid":false,"given":"Laura","family":"D'Adamo","sequence":"first","affiliation":[{"name":"Department of Psychological and Brain Sciences and Center for Weight, Eating, and Lifestyle Science (WELL Center) Drexel University  Philadelphia Pennsylvania USA"},{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9163-7055","authenticated-orcid":false,"given":"Anne Claire","family":"Grammer","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin N.","family":"Rackoff","sequence":"additional","affiliation":[{"name":"Department of Psychology The Pennsylvania State University  University Park Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7064-3835","authenticated-orcid":false,"given":"Ellen E.","family":"Fitzsimmons\u2010Craft","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4552-4361","authenticated-orcid":false,"given":"Sarah Ketchen","family":"Lipson","sequence":"additional","affiliation":[{"name":"Boston University School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle G.","family":"Newman","sequence":"additional","affiliation":[{"name":"Department of Psychology The Pennsylvania State University  University Park Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4564-6548","authenticated-orcid":false,"given":"C. 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