{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:24:00Z","timestamp":1790015040686,"version":"4.0.1"},"reference-count":62,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 112\u20102314\u2010B\u2010038\u2010047"],"award-info":[{"award-number":["NSTC 112\u20102314\u2010B\u2010038\u2010047"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004700","name":"Taipei Medical University","doi-asserted-by":"publisher","award":["TMU111\u2010AE1\u2010B01"],"award-info":[{"award-number":["TMU111\u2010AE1\u2010B01"]}],"id":[{"id":"10.13039\/501100004700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Bulimia nervosa (BN), a prevalent eating disorder characterized by recurrent binge\u2013purge cycles, may contribute to long\u2010term cardiovascular (CV) complications. However, evidence regarding these outcomes remains limited. This study investigated CV risks in patients with BN and the risk trajectory across varying follow\u2010up periods by using a nationwide Taiwanese cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from the National Health Insurance Research Database (2010\u20132022) were analyzed. Patients with BN aged 10\u201359\u2009years were matched with controls at a 1:10 ratio on the basis of sex, age, socioeconomic status, urbanization, and index year through propensity score matching. The composite CV outcomes included atherosclerosis, cardiac arrest, cardiomyopathy, conduction disorders, congestive heart failure, inflammatory heart diseases, ischemic heart diseases, stroke, valve diseases, and venous thromboembolism. Hazard ratios (HR) were estimated using Cox regression models adjusted for baseline psychiatric and physical comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The cumulative incidence of composite CV outcomes among patients with BN (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200911,682) was 10.0% after 10\u2009years of follow\u2010up. Patients with BN demonstrated a modest but significantly increased risk of composite CV outcomes (adjusted HR [aHR] 1.13 [95% CI, 1.03\u20131.23]), specifically those with psychiatric comorbidities (aHR 1.15 [95% CI, 1.03\u20131.29]) and with psychiatric hospitalization (aHR, 1.81 [95% CI, 1.25\u20132.61]). The risks of composite CV outcomes progressively increased across most follow\u2010up intervals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with BN exhibited a modest but persistently elevated CV risk. CV monitoring is particularly important for BN individuals with psychiatric comorbidities and those in need of psychiatric hospitalization for timely detection and management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/eat.24461","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T08:17:18Z","timestamp":1748333838000},"page":"1523-1534","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Bulimia Nervosa and Risk of Cardiovascular Outcomes: A Longitudinal Matched Cohort Study in Taiwan"],"prefix":"10.1002","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8940-0072","authenticated-orcid":false,"given":"Che\u2010Yin","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Shuang Ho Hospital Taipei Medical University  New Taipei City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0114-102X","authenticated-orcid":false,"given":"Mei\u2010Chih Meg","family":"Tseng","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Shuang Ho Hospital Taipei Medical University  New Taipei City Taiwan"},{"name":"Department of Psychiatry, School of Medicine, College of Medicine Taipei Medical University  Taipei Taiwan"},{"name":"Department of Psychiatry National Taiwan University College of Medicine  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5396-2586","authenticated-orcid":false,"given":"Kuan\u2010Rau","family":"Chiou","sequence":"additional","affiliation":[{"name":"Divison of Cardiology, Department of Internal Medicine, Shuang Ho Hospital Taipei Medical University  New Taipei City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0757-1901","authenticated-orcid":false,"given":"Joni Yu\u2010Hsuan","family":"Shao","sequence":"additional","affiliation":[{"name":"Graduate Institute of Biomedical Informatics Taipei Medical University  Taipei Taiwan"},{"name":"Clinical Big Data Research Center Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung\u2010Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"Health Data Analytics and Statistics Center, Office of Data Science Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2015.01.027"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593\u2010022\u201001071\u2010z"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.2087"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.2188\/jea.je20140076"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2014.1332"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyg296"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2018.20.1\/mdehert"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/00099228221134441"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.15167\/2421\u20104248\/jpmh2022.63.2S3.2772"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.7.659"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22501"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22984"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12865"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.06.017"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2463"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583\u2010199907000\u201000012"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2013.09.009"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.2147\/clep.S353435"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.2147\/clep.S273853"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.2147\/clep.S288518"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.5608"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0165\u20101781(98)00057\u20102"},{"issue":"3","key":"e_1_2_12_24_1","first-page":"157","article-title":"Accuracy of Diabetes Diagnosis in Health Insurance Claims Data in Taiwan","volume":"104","author":"Lin C. 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