{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:58:14Z","timestamp":1792511894134,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000724","name":"Health Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000724","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023239","name":"Oxford Academic Health Science Network","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023239","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014013","name":"UK Research and Innovation","doi-asserted-by":"publisher","award":["MR\/W002418\/1"],"award-info":[{"award-number":["MR\/W002418\/1"]}],"id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/X030539\/1"],"award-info":[{"award-number":["MR\/X030539\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019418","name":"NIHR Maudsley Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019418","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine baseline predictors of treatment completion and clinical outcomes in 16 to 25\u2010year\u2010olds referred for early intervention for a recent\u2010onset eating disorder (ED).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      Participants (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009228; 93% female, 63% White British) were drawn from the FREED\u2010Up study, which evaluated First episode Rapid Early intervention for EDs (FREED) in England across 2017\u20132018. Measures were completed at baseline and 3\u2010, 6\u2010 and 12\u2010months. Generalized estimating equations were used to identify baseline predictors of treatment completion and symptom remission by 12\u2010months. Linear mixed models were used to identify baseline predictors of change in global eating disorder examination\u2010questionnaire (EDE\u2010Q) scores, binge eating, purging and BMI (anorexia nervosa [AN] only) over 12\u2010months. Possible predictors included baseline ED symptoms, depression, anxiety, stress, psychosocial impairment, expressed emotion from close others, functioning against personalized goals, age, ethnicity, duration of illness, waiting times and BMI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no significant predictors of treatment completion. Lower stress at baseline predicted increased likelihood of symptom remission by 12\u2009months. Lower purging and psychosocial impairment at baseline predicted lower Global EDE\u2010Q scores over the following 12\u2009months; lower purging predicted lower rates of binge eating; and lower Global EDE\u2010Q scores, binge eating\u00a0and assessment waiting times predicted lower rates of purging. Higher purging at baseline was associated with higher BMI in AN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This study provides new data on predictors of treatment outcomes in an early intervention ED sample. In addition to ED symptoms and waiting times, psychosocial impairment and stress warrant consideration as factors that may influence treatment outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/eat.24593","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T11:51:20Z","timestamp":1762775480000},"page":"574-580","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Predictors of Treatment Outcome in an Early Intervention Eating Disorder Sample"],"prefix":"10.1002","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2896-6459","authenticated-orcid":false,"given":"Karina L.","family":"Allen","sequence":"first","affiliation":[{"name":"South London and Maudsley NHS Foundation Trust  London UK"},{"name":"Centre for Research in Eating and Weight Disorders, Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4979-4847","authenticated-orcid":false,"given":"Amelia","family":"Austin","sequence":"additional","affiliation":[{"name":"Centre for Research in Eating and Weight Disorders, Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"},{"name":"Mathison Centre for Mental Health Research &amp; Education, Cumming School of Medicine University of Calgary  Calgary Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0208-1492","authenticated-orcid":false,"given":"Michaela","family":"Flynn","sequence":"additional","affiliation":[{"name":"Centre for Research in Eating and Weight Disorders, Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"},{"name":"Inside Out Institute  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0704-8619","authenticated-orcid":false,"given":"Danielle","family":"Glennon","sequence":"additional","affiliation":[{"name":"South London and Maudsley NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1932-1723","authenticated-orcid":false,"given":"Victoria A.","family":"Mountford","sequence":"additional","affiliation":[{"name":"Sage Clinics  Dubai UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6994-1472","authenticated-orcid":false,"given":"Amy","family":"Brown","sequence":"additional","affiliation":[{"name":"Sussex Partnership NHS Foundation Trust  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Franklin\u2010Smith","sequence":"additional","affiliation":[{"name":"Leeds and York Partnership NHS Foundation Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9516-5534","authenticated-orcid":false,"given":"William Rhys","family":"Jones","sequence":"additional","affiliation":[{"name":"Central and North West London NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Brady","sequence":"additional","affiliation":[{"name":"North East London NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Nunes","sequence":"additional","affiliation":[{"name":"North East London NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Connan","sequence":"additional","affiliation":[{"name":"North East London NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Mahony","sequence":"additional","affiliation":[{"name":"University College London Division of Psychology and Language Sciences  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8543-8383","authenticated-orcid":false,"given":"Lucy","family":"Serpell","sequence":"additional","affiliation":[{"name":"University College London Division of Psychology and Language Sciences  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1335-1937","authenticated-orcid":false,"given":"Ulrike","family":"Schmidt","sequence":"additional","affiliation":[{"name":"South London and Maudsley NHS Foundation Trust  London UK"},{"name":"Centre for Research in Eating and Weight Disorders, Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14733140412331383913"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psycom.2025.100217"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/eip.13139"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14733145.2012.729069"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2008.06.012"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4679(198805)44:3<392::AID-JCLP2270440313>3.0.CO;2-3"},{"key":"e_1_2_9_8_1","first-page":"313","article-title":"Eating Disorder Examination Questionnaire","volume":"309","author":"Fairburn C. G.","year":"2008","journal-title":"Cognitive Behavior Therapy and Eating Disorders"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-9-67"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2797"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/eip.12881"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2020.00432"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.2013"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22850"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22838"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-7967(94)00075-U"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.3154"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2018.0621"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2008.02.003"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23504"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.180.5.461"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23373"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/wps.21182"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1201\/9780429092060"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22411"}],"container-title":["International Journal of Eating Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.24593","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/eat.24593","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.24593","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:39:12Z","timestamp":1773293952000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/eat.24593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/eat.24593"],"URL":"https:\/\/doi.org\/10.1002\/eat.24593","archive":["Portico"],"relation":{},"ISSN":["0276-3478","1098-108X"],"issn-type":[{"value":"0276-3478","type":"print"},{"value":"1098-108X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,10]]},"assertion":[{"value":"2025-07-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}