{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T09:03:47Z","timestamp":1780563827767,"version":"3.54.1"},"reference-count":65,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010809","name":"Jascha Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010727","name":"Axel Muusfeldts Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007403","name":"Dagmar Marshalls Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007403","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006088","name":"Direkt\u00f8r Emil C. 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This study aimed to identify distinct trajectories of change in body mass index (BMI) and depressive symptoms during inpatient treatment, examine clinical predictors and outcomes, and test reciprocal associations between BMI and depressive symptom changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Weekly BMI and depressive symptom data were collected from 156 inpatients with AN (mean treatment duration\u2009=\u200911.6\u2009weeks). Growth mixture modeling identified trajectory classes. Baseline clinical variables were examined as predictors, and discharge outcomes were compared across classes. A joint Bayesian growth model was used to examine longitudinal associations between BMI and depressive symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Three BMI trajectories were identified: steady increase (58.3%; higher baseline BMI with consistent gains), gradual weight gain (28.9%; low baseline BMI with steady gains), and rapid response (12.8%; low baseline BMI with early rapid gain followed by slowing or decline). Two depressive symptom trajectories emerged: severe\u2010stable and moderate\u2010improving. The severe\u2010stable group was predicted by higher trauma\u2010related comorbidity (OR 11.11,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009) and eating psychopathology (OR 3.23,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Depressive symptom class was associated with initial BMI but not BMI change, while BMI classes predicted the curvature of depressive symptom trajectories. No credible week\u2010to\u2010week associations emerged between BMI and depressive symptom changes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Findings highlight substantial heterogeneity in treatment response. Rapid early weight gain in patients with extremely low BMI and high severity may not indicate sustained improvement. Persistent depressive symptoms, especially in those with trauma histories, underscore the need for trauma\u2010informed care alongside weight restoration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/eat.70047","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T11:26:08Z","timestamp":1770809168000},"page":"1289-1303","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Latent Trajectories of Body Mass Index and Depressive Symptoms in Inpatients With Anorexia Nervosa: Predictors and Outcomes"],"prefix":"10.1002","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8877-0138","authenticated-orcid":false,"given":"Matteo","family":"Martini","sequence":"first","affiliation":[{"name":"Eating Disorders Center, Department of Neuroscience \u201cRita Levi Montalcini\u201d University of Turin  Turin Italy"},{"name":"Center of Eating and Feeding Disorders Research 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Bryde","family":"Christensen","sequence":"additional","affiliation":[{"name":"Center of Eating and Feeding Disorders Research (CEDaR), Psychiatric Center Ballerup Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Sj\u00f6gren","sequence":"additional","affiliation":[{"name":"National Highly Specialized Care for Eating Disorder, Region V\u00e4sternorrland and Institute for Clinical Science, Department of Psychiatry Ume\u00e5 University  Sundsvall Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5571-2273","authenticated-orcid":false,"given":"Nadia","family":"Micali","sequence":"additional","affiliation":[{"name":"Center of Eating and Feeding Disorders Research (CEDaR), Psychiatric Center Ballerup Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"},{"name":"Great Ormond Street Institute of Child Health, 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