{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:03:33Z","timestamp":1788966213308,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["K24MH135189"],"award-info":[{"award-number":["K24MH135189"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["K23MH139989"],"award-info":[{"award-number":["K23MH139989"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Eating Disorders"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Cognitive\u2010behavioral therapy for ARFID (CBT\u2010AR) has demonstrated preliminary efficacy in open trials, but no studies have examined its effectiveness in real\u2010world settings. We evaluated the effectiveness of virtually delivered CBT\u2010AR for adults with ARFID and examined whether baseline symptom severity within each ARFID profile predicted corresponding symptom improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      <jats:italic>N\u2009=<\/jats:italic>\n                      \u2009549 adults with ARFID received CBT\u2010AR through Equip Health. We collected weight and Pica, ARFID, and Rumination Disorder Interview\u2013ARFID Questionnaire data at intake and throughout treatment. Ordinary least squares regressions examined changes in weight and ARFID symptoms, and whether baseline severity within each profile predicted improvement in that domain, controlling for severity in other profiles and demographic\/clinical covariates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients requiring weight restoration (\n                      <jats:italic>n\u2009=<\/jats:italic>\n                      \u2009243) gained an average of 0.34 lb (0.15\u2009kg) per week (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). In the full sample, patients demonstrated significant reductions in sensory sensitivity (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u2009\u22120.05, 95% CI [\u22120.07, \u22120.04]), fear of aversive consequences (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u2009\u22120.04, 95% CI [\u22120.05, \u22120.02]), and lack of interest in food\/eating (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u2009\u22120.04, 95% CI [\u22120.05, \u22120.03]; all\n                      <jats:italic>p<\/jats:italic>\n                      s\u2009&lt;\u20090.001). Greater baseline severity within each profile uniquely predicted greater improvement in the corresponding profile (all\n                      <jats:italic>bs<\/jats:italic>\n                      \u2009=\u2009\u22120.03, all\n                      <jats:italic>ps<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>CBT\u2010AR delivered virtually under naturalistic conditions is effective for adults with ARFID, producing significant improvements in weight and ARFID symptoms. Though randomized controlled trials are needed to establish definitive efficacy, findings provide preliminary support for dissemination beyond specialized research settings and demonstrate the clinical utility of profile\u2010based treatment planning.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/eat.70098","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T04:59:37Z","timestamp":1775710777000},"page":"1663-1672","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effectiveness of Virtually Delivered Cognitive\u2010Behavioral Therapy for Avoidant\/Restrictive Food Intake Disorder"],"prefix":"10.1002","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1950-3332","authenticated-orcid":false,"given":"P. Evelyna","family":"Kambanis","sequence":"first","affiliation":[{"name":"Eating Disorders Clinical and Research Program Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Mass General Brigham Multidisciplinary Eating Disorders Research Collaborative  Boston Massachusetts USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6853-9543","authenticated-orcid":false,"given":"Kelly","family":"Cai","sequence":"additional","affiliation":[{"name":"AMC Department of Psychiatry Mass General Brigham  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2601-581X","authenticated-orcid":false,"given":"Jennifer J.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Eating Disorders Clinical and Research Program Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Mass General Brigham Multidisciplinary Eating Disorders Research Collaborative  Boston Massachusetts USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1586-0930","authenticated-orcid":false,"given":"Kamryn T.","family":"Eddy","sequence":"additional","affiliation":[{"name":"Eating Disorders Clinical and Research Program Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Mass General Brigham Multidisciplinary Eating Disorders Research Collaborative  Boston Massachusetts USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston Massachusetts USA"},{"name":"AMC Department of Psychiatry Mass General Brigham  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4914-0226","authenticated-orcid":false,"given":"David","family":"Freestone","sequence":"additional","affiliation":[{"name":"Equip Health  Carlsbad California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3997-2398","authenticated-orcid":false,"given":"Jessica","family":"Baker","sequence":"additional","affiliation":[{"name":"Equip Health  Carlsbad California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4294-2680","authenticated-orcid":false,"given":"Jessie","family":"Menzel","sequence":"additional","affiliation":[{"name":"Equip Health  Carlsbad California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1384-7177","authenticated-orcid":false,"given":"Eliane","family":"Boucher","sequence":"additional","affiliation":[{"name":"Equip Health  Carlsbad California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22958"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40337\u2010022\u201000706\u20107"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23761"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.24126"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23711"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v034.i02"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.2105\/ajph.93.8.1261"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23973"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.24355"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2024.04.010"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.02959"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23077"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/2167702613497932"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/10640266.2024.2346372"},{"key":"e_1_2_13_17_1","unstructured":"R Core Team.2022.\u201cR: A Language and Environment for Statistical Computing.\u201dR Foundation for Statistical Computing.https:\/\/www.R\u2010project.org\/."},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23341"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbct.2020.10.004"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23355"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmcpc1616394"},{"key":"e_1_2_13_22_1","volume-title":"Cognitive\u2010Behavioral Therapy for Avoidant\/Restrictive Food Intake Disorder: Children, Adolescents, and Adults","author":"Thomas J. J.","year":"2019"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23602"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.01686"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.70087"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22996"}],"container-title":["International Journal of Eating Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.70098","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/eat.70098","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eat.70098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T14:05:31Z","timestamp":1786025131000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/eat.70098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,8]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/eat.70098"],"URL":"https:\/\/doi.org\/10.1002\/eat.70098","archive":["Portico"],"relation":{},"ISSN":["0276-3478","1098-108X"],"issn-type":[{"value":"0276-3478","type":"print"},{"value":"1098-108X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,8]]},"assertion":[{"value":"2026-01-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}