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Whereas the original host survives infestations by this parasite, they are lethal to colonies of its new host. Here, we investigated a population of <jats:italic>A.\u00a0cerana<\/jats:italic> naturally infested by the <jats:italic>V.\u00a0destructor<\/jats:italic> Korea haplotype that gave rise to the globally invasive mite lineage. Our aim was to better characterize traits that allow for the survival of the original host to infestations by this particular mite haplotype. A known major trait of resistance is the lack of mite reproduction on worker brood in <jats:italic>A.\u00a0cerana<\/jats:italic>. We show that this trait is neither due to a lack of host attractiveness nor of reproduction initiation by the parasite. However, successful mite reproduction was prevented by abnormal host development. Adult <jats:italic>A.\u00a0cerana<\/jats:italic> workers recognized this state and removed hosts and parasites, which greatly affected the fitness of the parasite. These results confirm and complete previous observations of brood susceptibility to infestation in other honeybee host populations, provide new insights into the coevolution between hosts and parasites in this system, and may contribute to mitigating the large\u2010scale colony losses of <jats:italic>A.\u00a0mellifera<\/jats:italic> due to <jats:italic>V.\u00a0destructor<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/ece3.3802","type":"journal-article","created":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T02:08:42Z","timestamp":1516673322000},"page":"2135-2145","source":"Crossref","is-referenced-by-count":39,"title":["Reproduction of parasitic mites <i>Varroa destructor<\/i> in original and new honeybee hosts"],"prefix":"10.1002","volume":"8","author":[{"given":"Zheguang","family":"Lin","sequence":"first","affiliation":[{"name":"College of Animal Sciences Zhejiang University  Hangzhou China"},{"name":"Agroscope Swiss Bee Research Center  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Qin","sequence":"additional","affiliation":[{"name":"College of Animal Sciences Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Page","sequence":"additional","affiliation":[{"name":"Agroscope Swiss Bee Research Center  Bern Switzerland"},{"name":"Vetsuisse Faculty Institute of Bee Health University of Bern  Bern Switzerland"},{"name":"Plant Bioactive Compound Laboratory Faculty of Agriculture Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Animal Sciences Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"College of Animal Sciences Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengsheng","family":"Wen","sequence":"additional","affiliation":[{"name":"College of Animal Sciences Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuliang","family":"Hu","sequence":"additional","affiliation":[{"name":"College of Animal Sciences Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5163-5215","authenticated-orcid":false,"given":"Peter","family":"Neumann","sequence":"additional","affiliation":[{"name":"Vetsuisse Faculty Institute of Bee Health University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8499-0694","authenticated-orcid":false,"given":"Huoqing","family":"Zheng","sequence":"additional","affiliation":[{"name":"College of Animal Sciences Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Dietemann","sequence":"additional","affiliation":[{"name":"Agroscope Swiss Bee Research Center  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1603\/0022-0493(2004)097[0741:APIWHB]2.0.CO;2"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006456720416"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/342143"},{"key":"e_1_2_9_5_1","unstructured":"Bates D. 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