{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:49:49Z","timestamp":1791218989144,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T00:00:00Z","timestamp":1531440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["RO1 AI101112"],"award-info":[{"award-number":["RO1 AI101112"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ecology and Evolution"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Aedes aegypti<\/jats:italic>, the major vector of dengue, yellow fever, chikungunya, and Zika viruses, remains of great medical and public health concern. There is little doubt that the ancestral home of the species is Africa. This mosquito invaded the New World 400\u2010500\u00a0years ago and later, Asia. However, little is known about the genetic structure and history of <jats:italic>Ae.\u00a0aegypti<\/jats:italic> across Africa, as well as the possible origin(s) of the New World invasion. Here, we use ~17,000 genome\u2010wide single nucleotide polymorphisms (<jats:styled-content style=\"fixed-case\">SNP<\/jats:styled-content>s) to characterize a heretofore undocumented complex picture of this mosquito across its ancestral range in Africa. We find signatures of human\u2010assisted migrations, connectivity across long distances in sylvan populations, and of local admixture between domestic and sylvan populations. Finally, through a phylogenetic analysis combined with the genetic structure analyses, we suggest West Africa and especially Angola as the source of the New World's invasion, a scenario that fits well with the historic record of 16th\u2010century slave trade between Africa and Americas.<\/jats:p>","DOI":"10.1002\/ece3.4278","type":"journal-article","created":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T12:16:07Z","timestamp":1531484167000},"page":"7835-7848","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":83,"title":["Population structure of a vector of human diseases: <i>Aedes aegypti<\/i> in its ancestral range, Africa"],"prefix":"10.1002","volume":"8","author":[{"given":"Panayiota","family":"Kotsakiozi","sequence":"first","affiliation":[{"name":"Yale University  New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin R.","family":"Evans","sequence":"additional","affiliation":[{"name":"Yale University  New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5401-3988","authenticated-orcid":false,"given":"Andrea","family":"Gloria\u2010Soria","sequence":"additional","affiliation":[{"name":"Yale University  New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basile","family":"Kamgang","sequence":"additional","affiliation":[{"name":"Centre for Research in Infectious Diseases  P.O. 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