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In the Baltic Sea, a large brackish water system in northern Europe, previous research has suggested that this deficiency is associated with lipid\u2010rich diets with a high proportion of docosahexaenoic acid (DHA, 22:6n\u20103). The mechanism proposed is that a diet abundant in highly unsaturated fatty acids, such as DHA, depletes thiamine as an antioxidant defense in adult salmonids, rather than allocating thiamine to the offspring. In light of this existing hypothesis, we here explore the relationship between diet history and the related fatty acid (FA), profiles, and thiamine status of Atlantic salmon (<jats:italic>Salmo salar<\/jats:italic> L.) in three systems: the Baltic Sea, the North Atlantic Ocean, and Lake V\u00e4nern. Atlantic salmon inhabiting each system is known to have unique feeding histories and thiamine status. Our results showed that despite extensive sampling effort and distinct FA profiles, indicative of their diverse diets, there were no correlations between any FAs, including DHA, and the thiamine status of these populations. This finding does not support the above\u2010mentioned hypothesis that diets rich in easily oxidized FAs would lead to lower thiamine concentrations in salmon tissues. Additionally, we found that changes in the salmon FA profiles throughout their life cycle are consistent for both low\u2010thiamine populations from the Baltic Sea and medium\u2010thiamine populations from North Atlantic Ocean, suggesting that these changes might not be involved in thiamine deficiency development.<\/jats:p>","DOI":"10.1002\/ece3.70478","type":"journal-article","created":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T02:39:23Z","timestamp":1729910363000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Implications of Atlantic Salmon (<i>Salmo salar<\/i> L.) Fatty Acid Profiles for Their Thiamine Status"],"prefix":"10.1002","volume":"14","author":[{"given":"Vittoria","family":"Todisco","sequence":"first","affiliation":[{"name":"Centre for Ecology and Evolution in Microbial Model Systems (EEMiS) Linnaeus University  Kalmar Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc\u00a0M.","family":"Hauber","sequence":"additional","affiliation":[{"name":"Centre for Ecology and Evolution in Microbial Model Systems (EEMiS) Linnaeus University  Kalmar Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael\u00a0T.","family":"Brett","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering (CEE) University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Ax\u00e9n","sequence":"additional","affiliation":[{"name":"Swedish Veterinary Agency (SVA)  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjetil","family":"Hindar","sequence":"additional","affiliation":[{"name":"Norwegian Institute for Nature Research (NINA)  Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petter","family":"Tibblin","sequence":"additional","affiliation":[{"name":"Centre for Ecology and Evolution in Microbial Model Systems (EEMiS) Linnaeus University  Kalmar Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3740-5998","authenticated-orcid":false,"given":"Samuel","family":"Hylander","sequence":"additional","affiliation":[{"name":"Centre for Ecology and Evolution in Microbial Model Systems (EEMiS) Linnaeus University  Kalmar Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-406X(67)90781-5"},{"key":"e_1_2_10_3_1","unstructured":"Amcoff P. H.B\u00f6rjeson J.Lindeberg andL.Norrgren.1998.\u201cThiamine Concentrations in Feral Baltic Salmon Exhibiting the M74 Syndrome.\u201dPaper Presented at the Early Life Stage Mortality Syndrome in Fishes of the Great Lakes and Baltic Sea. 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