{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:04:06Z","timestamp":1788566646188,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007753","name":"Agenzia Regionale per i Parchi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007753","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ecology and Evolution"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>In the current era of global change, the emergence of infectious diseases at the wildlife\u2013livestock interface poses risks to biodiversity, agricultural economies, and public health. Driven by anthropogenic influence, increased sharing of resources between wildlife and livestock can promote cross\u2010species transmission, the consequences of which are challenging to predict. <jats:styled-content style=\"fixed-case\"><jats:italic>Mycoplasma bovis<\/jats:italic><\/jats:styled-content> , an economically important bacterial pathogen in cattle, has recently emerged as a threat to other ungulate species. This study reports on a case of <jats:styled-content style=\"fixed-case\"><jats:italic>M. bovis<\/jats:italic><\/jats:styled-content> in an intensively monitored free\u2010ranging mule deer (<jats:styled-content style=\"fixed-case\"><jats:italic>Odocoileus hemionus<\/jats:italic><\/jats:styled-content> ) in Colorado, USA, which presented an opportunity to describe the disease in a novel host and infer transmission and infection dynamics from GPS collar data. Following a mortality signal from a GPS\u2010collared adult female mule deer, field investigation revealed predation while postmortem examination further revealed severe, acute, fibrinosuppurative and necrotizing pleuropneumonia. Histopathological analysis, immunohistochemistry, and real\u2010time PCR confirmed <jats:styled-content style=\"fixed-case\"><jats:italic>M. bovis<\/jats:italic><\/jats:styled-content> as the etiology. GPS collar data demonstrated spatial overlap with dairy cattle in the 50\u2009days prior to death, implicating potential spillover from cattle as the transmission pathway. Reduced movement was identified 19\u2009days prior to death, indicative of sickness behavior due to acute pneumonia. This case underscores the potential for <jats:styled-content style=\"fixed-case\"><jats:italic>M. bovis<\/jats:italic><\/jats:styled-content> to cause severe disease in wild ungulates and highlights the value of thorough postmortem investigations as a routine component of studies involving wildlife tracking. The retrospective use of GPS collar data provides valuable insights into the movement ecology of wildlife exposed to novel pathogens, aiding in the understanding of cross\u2010species transmission and informing management strategies to reduce the potential for spillover.<\/jats:p>","DOI":"10.1002\/ece3.71182","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T03:57:26Z","timestamp":1744343846000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cross\u2013Species Transmission at the Wildlife\u2013Livestock Interface: A Case Study of Epidemiological Inference From Mule Deer <scp>GPS<\/scp> Collar Data"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9066-721X","authenticated-orcid":false,"given":"Jennifer L.","family":"Malmberg","sequence":"first","affiliation":[{"name":"National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service United States Department of Agriculture  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Alder","sequence":"additional","affiliation":[{"name":"Department of Fish, Wildlife and Conservation Biology Colorado State University  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halcyon","family":"Killion","sequence":"additional","affiliation":[{"name":"Wyoming State Veterinary Laboratory  Laramie Wyoming USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Buttke","sequence":"additional","affiliation":[{"name":"Biological Resources Division National Park Service  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9931-8312","authenticated-orcid":false,"given":"Kim M.","family":"Pepin","sequence":"additional","affiliation":[{"name":"National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service United States Department of Agriculture  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1640-5355","authenticated-orcid":false,"given":"George","family":"Wittemyer","sequence":"additional","affiliation":[{"name":"Department of Fish, Wildlife and Conservation Biology Colorado State University  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tree.2020.10.018"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-021-00639-z"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ece3.11418"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/af\/vfad064"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2012.11.018"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1365-2656.13661"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.62.10.4580-4586.1994"},{"key":"e_1_2_10_9_1","first-page":"456","article-title":"Spillover of Highly Pathogenic Avian Influenza H5N1 Virus to Dairy Cattle","volume":"1","author":"Caserta L. 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