{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T03:49:57Z","timestamp":1791431397580,"version":"4.3.3"},"reference-count":79,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32301320"],"award-info":[{"award-number":["32301320"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ecology and Evolution"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Traditional theory posits that phenotypic integration\u2014the structured covariation among traits\u2014constrains phenotypic plasticity, thereby limiting adaptive responses. In contrast, emerging perspectives suggest integration may instead facilitate plasticity through coordinated trait adjustments. The mechanistic basis of this relationship, particularly how differential plasticity among traits shapes integration, remains empirically unresolved. To test these competing hypotheses, we exposed five genotypes of an asexual\n                    <jats:italic>Daphnia<\/jats:italic>\n                    cf.\n                    <jats:italic>pulex<\/jats:italic>\n                    to a factorial design of six temperature\u2009\u00d7\u2009food environments. We measured key functional traits (activities of five digestive enzymes and body length) and quantified phenotypic integration, trait plasticity, and differential plasticity. We then assessed: (i) how genotype and environment shape integration structure, (ii) the relationship between integration strength and plasticity magnitude, and (iii) how integration shapes correlated versus differential plasticity across environments. Our results show that phenotypic integration is itself highly plastic, dynamically reconfigured by genotype\u2010by\u2010environment interactions. The integration\u2013plasticity relationship was context\u2010dependent: under low\u2010food conditions, stronger integration was associated with greater plasticity, supporting a facilitative rather than constraining role in this system. Notably, the stability of trait correlations across environments declined significantly as the magnitude of differential plasticity between traits increased. This identifies plasticity coordination as the mechanistic link through which integration buffers organisms against environmental variation. Variation in integration and plasticity was independent of pairwise genetic distance among clones. Our findings challenge the classic constraint model by demonstrating that phenotypic integration is a labile property that facilitates functional plasticity through coordinated trait adjustments. Specifically, variation in differential plasticity serves as a critical mechanistic determinant of this process. This capacity for context\u2010dependent reorganization of trait relationships is largely decoupled from genetic constraints in our study system. It positions integration as a potential dynamic facilitator of rapid adaptation, potentially underpinning the success of asexual lineages in fluctuating environments.\n                  <\/jats:p>","DOI":"10.1002\/ece3.74304","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T06:04:28Z","timestamp":1789106668000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Phenotypic Integration Facilitates Plasticity Through Reorganization of Traits Under Multiple Stress: Evidence From Asexual Water Flea Genotypes"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7273-6672","authenticated-orcid":false,"given":"Xiaofei","family":"Tian","sequence":"first","affiliation":[{"name":"Fishery College Zhejiang Ocean University  Zhoushan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenping","family":"Feng","sequence":"additional","affiliation":[{"name":"Fishery College Zhejiang Ocean University  Zhoushan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5200-989X","authenticated-orcid":false,"given":"Xiumei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Fishery College Zhejiang Ocean University  Zhoushan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2008.1671"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsbl.2020.0580"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1365-2745.13668"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.134.3.861-874.1978"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.150.3692.28"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.18418"},{"key":"e_1_2_11_9_1","volume-title":"Model Selection and Multimodel Inference: A Practical Information\u2010Theoretic Approach","author":"Burnham K. 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G.","year":"2016","journal-title":"Annals of Botany Plants"}],"container-title":["Ecology and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ece3.74304","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ece3.74304","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ece3.74304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:59:08Z","timestamp":1791428348000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ece3.74304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":79,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/ece3.74304"],"URL":"https:\/\/doi.org\/10.1002\/ece3.74304","archive":["Portico"],"relation":{},"ISSN":["2045-7758","2045-7758"],"issn-type":[{"value":"2045-7758","type":"print"},{"value":"2045-7758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2026-05-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e74304"}}