{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T03:49:27Z","timestamp":1791431367186,"version":"4.3.3"},"reference-count":64,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ecology and Evolution"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Streptomyces sampsonii<\/jats:italic>\n                    <\/jats:styled-content>\n                    is a promising biocontrol bacterium, but its genomic basis of adaptation and secondary metabolism remains unclear. Here, we present a chromosome\u2010level genome assembly of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. sampsonii<\/jats:italic>\n                    <\/jats:styled-content>\n                    (7.20\u2009Mb, 6015 protein\u2010coding genes) and perform comparative analyses with 95 related\n                    <jats:italic>Streptomyces<\/jats:italic>\n                    species. Phylogenomic and synteny analyses revealed its closest relationship with\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. albidoflavus<\/jats:italic>\n                    <\/jats:styled-content>\n                    , while extensive structural variations distinguished more distant lineages. Pangenome analysis uncovered 84,178 gene clusters, with pan_shell and pan_cloud genes predominantly enriched in xenobiotic biodegradation, metabolism, and antibiotic biosynthesis, highlighting their roles in ecological adaptation and biocontrol potential. Biosynthetic gene cluster (BGC) analysis identified numerous NRPS, PKS, and terpene pathways, many of which belong to pan_shell and pan_cloud regions, suggesting dynamic evolutionary origins. We further detected 66,260 horizontally transferred (HGT) genes, including 438 in BGCs, underscoring HGT as a major driver of metabolic innovation. Together, these findings provide novel insights into the genomic diversity, adaptive capacity, and secondary metabolic potential of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. sampsonii<\/jats:italic>\n                    <\/jats:styled-content>\n                    and its close relatives.\n                  <\/jats:p>","DOI":"10.1002\/ece3.74350","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T22:36:50Z","timestamp":1789511810000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pangenome of\n                    <scp>\n                      <i>Streptomyces sampsonii<\/i>\n                    <\/scp>\n                    and Relatives Highlights Horizontal Gene Transfer and Secondary Metabolism in Environmental Adaptation and Ecological Significance"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8455-9913","authenticated-orcid":false,"given":"Boyang","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Architecture and Art Hebei University of Architecture  Zhangjiakou Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Energy Engineering Hebei University of Architecture  Zhangjiakou Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.01533\u201019"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059\u2010022\u201002823\u20107"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/genomea.00470\u201016"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579\u2010021\u201000650\u20104"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/417141a"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864\u2010016\u20103382\u2010y"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.677558"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msab293"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab688"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/imt2.107"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864\u2010019\u20106137\u20108"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2320170121"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao2136"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aar4120"},{"key":"e_1_2_10_16_1","unstructured":"Eddy S. 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