{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T03:49:27Z","timestamp":1787888967525,"version":"build-2784847793"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T00:00:00Z","timestamp":1658620800000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008982","name":"National Science Foundation of Sri Lanka","doi-asserted-by":"publisher","award":["DOB\/DEB\u20101737877"],"award-info":[{"award-number":["DOB\/DEB\u20101737877"]}],"id":[{"id":"10.13039\/501100008982","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ecology and Evolution"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Many mycophagous <jats:italic>Drosophila<\/jats:italic> species have adapted to tolerate high concentrations of mycotoxins, an ability not reported in any other eukaryotes. Although an association between mycophagy and mycotoxin tolerance has been established in many <jats:italic>Drosophila<\/jats:italic> species, the genetic mechanisms of the tolerance are unknown. This study presents the inter\u2010 and intraspecific variation in the mycotoxin tolerance trait. We studied the mycotoxin tolerance in four <jats:italic>Drosophila<\/jats:italic> species from four separate clades within the <jats:italic>immigrans<\/jats:italic>\u2010<jats:italic>tripunctata<\/jats:italic> radiation from two distinct locations. The effect of mycotoxin treatment on 20 isofemale lines per species was studied using seven gross phenotypes: survival to pupation, survival to eclosion, development time to pupation and eclosion, thorax length, fecundity, and longevity. We observed interspecific variation among four species, with <jats:italic>D.\u00a0falleni<\/jats:italic> being the most tolerant, followed by <jats:italic>D.\u00a0recens<\/jats:italic>, <jats:italic>D.\u00a0neotestacea<\/jats:italic>, and <jats:italic>D.\u00a0tripunctata<\/jats:italic>, in that order. The results also revealed geographical variation and intraspecific genetic variation in mycotoxin tolerance. This report provides the foundation for further delineating the genetic mechanisms of the mycotoxin tolerance trait.<\/jats:p>","DOI":"10.1002\/ece3.9126","type":"journal-article","created":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T23:39:00Z","timestamp":1658705940000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Inter\u2010 and intraspecific variation in mycotoxin tolerance: A\u00a0study of four <i>Drosophila<\/i> species"],"prefix":"10.1002","volume":"12","author":[{"given":"Prajakta P.","family":"Kokate","sequence":"first","affiliation":[{"name":"Department of Biological Sciences Michigan Technological University  Houghton Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences Michigan Technological University  Houghton Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucinda","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences Michigan Technological University  Houghton Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Mathematical Sciences Michigan Technological University  Houghton Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8865-365X","authenticated-orcid":false,"given":"Thomas","family":"Werner","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences Michigan Technological University  Houghton Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"e_1_2_9_4_1","first-page":"225","volume-title":"Advances in ecological research","author":"Courtney S. 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Steenwinkel T. &Jaenike J.(2020).The encyclopedia of North American Drosophilids volume 2: Drosophilids of the Southeast."},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.9b00414"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.zool.2018.05.005"}],"container-title":["Ecology and Evolution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ece3.9126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ece3.9126","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ece3.9126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T22:50:44Z","timestamp":1692658244000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ece3.9126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":28,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1002\/ece3.9126"],"URL":"https:\/\/doi.org\/10.1002\/ece3.9126","archive":["Portico"],"relation":{},"ISSN":["2045-7758","2045-7758"],"issn-type":[{"value":"2045-7758","type":"print"},{"value":"2045-7758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"2022-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9126"}}