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The SARS\u2010CoV\u20102 virus has multiple potential pathophysiologic interconnections with endocrine systems, potentially causing disturbances in glucose metabolism, hypothalamic and pituitary function, adrenal function and mineral metabolism. A growing body of data is revealing both the effects of underlying endocrine disorders on COVID\u201019 disease outcome and the effects of the SARS\u2010CoV\u20102 virus on endocrine systems. However, comprehensive assessment of the relationship to endocrine disorders in children has been lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Content<\/jats:title><jats:p>In this review, we present the effects of SARS\u2010CoV\u20102 infection on endocrine systems and review the current literature on complications of COVID\u201019 disease in underlying paediatric endocrine disorders. We provide recommendations on management of endocrinopathies related to SARS\u2010CoV\u20102 infection in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Summary and outlook<\/jats:title><jats:p>With the surge in COVID\u201019 cases worldwide, it is important for paediatric endocrinologists to be aware of the interaction of SARS\u2010CoV\u20102 with the endocrine system and management considerations for patients with underlying disorders who develop COVID\u201019 disease. While children and adults share some risk factors that influence risk of complications in SARS\u2010CoV\u20102 infection, it is becoming clear that responses in the paediatric population are distinct and outcomes from adult studies cannot be extrapolated. Evidence emerging from paediatric studies provides some guidance but highlights the need for more research in this area.<\/jats:p><\/jats:sec>","DOI":"10.1002\/edm2.262","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T09:38:30Z","timestamp":1622799510000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["SARS\u2010CoV\u20102 infection and paediatric endocrine disorders: Risks and management considerations"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2656-7211","authenticated-orcid":false,"given":"Ryan","family":"Miller","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Maryland School of Medicine Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0692-6624","authenticated-orcid":false,"given":"Ambika P.","family":"Ashraf","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5788-7955","authenticated-orcid":false,"given":"Evgenia","family":"Gourgari","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Georgetown University Washington D.C. 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