{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T13:27:12Z","timestamp":1793626032114,"version":"4.5.1"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Endocrino Diabet &amp;amp; Metabol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Diabetes mellitus is a major global health challenge that is controlled through insulin therapy; however, its use is limited by several barriers. This study assessed physicians' perceptions of insulin use, associated barriers and suggested improvements in a tertiary care hospital in Lahore, Pakistan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>A cross\u2010sectional survey was conducted at a tertiary care public sector hospital of Lahore, Pakistan, from September 2024 to February 2025. A total of 808 physicians participated. Data were collected through a questionnaire and analysed using descriptive and inferential statistics. Chi\u2010square, Kruskal\u2013Wallis, Bonferroni post hoc tests and binary logistic regression were applied using IBM SPSS Version 27.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 808 physicians, 369 were males, and 439 were females. Most had 5\u201310\u2009years of clinical experience, with medicine as the largest speciality. Common barriers to insulin therapy included patient resistance, hypoglycaemia, regimen complexity, cultural beliefs and limited resources. Male physicians were more likely to report barriers in both unadjusted and adjusted analyses (OR\u2009=\u20091.414,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.015; AOR\u2009=\u20091.392,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.024). MRCP\u2010qualified physicians also had higher odds of reporting barriers (OR\u2009=\u20091.642,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.034; AOR\u2009=\u20091.657,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.042). Physicians with 5\u201310\u2009years' experience were less likely to report barriers than those with &lt;\u20095\u2009years (OR\u2009=\u20090.557,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001; AOR\u2009=\u20090.588,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Physicians recommended that diabetes educators and regular follow\u2010up can improve adherence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Major barriers to insulin therapy included patient resistance, inadequate education, cultural beliefs, financial constraints and fear of hypoglycaemia. Physicians emphasized the need for better patient education, regular follow\u2010up and improved communication to enhance insulin adherence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/edm2.70337","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:39:26Z","timestamp":1789155566000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Insulin Prescribing Challenges and Physician\u2010Suggested Interventions: Evidence From a Tertiary Care Hospital in Lahore, Pakistan"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4471-676X","authenticated-orcid":false,"given":"Muhammad","family":"Aamir","sequence":"first","affiliation":[{"name":"Faculty of Pharmacy University of Lahore  Lahore Punjab Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bazila","family":"Nafeesa","sequence":"additional","affiliation":[{"name":"Department of Pharmacy University of Lahore  Lahore Punjab Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3436-1467","authenticated-orcid":false,"given":"Adeel","family":"Aslam","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice and Clinical Pharmacy, Faculty of Pharmacy Universiti Teknologi MARA (UiTM) Cawangan Selangor  Puncak Alam Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6374-3506","authenticated-orcid":false,"given":"Asma","family":"Ghulam Mustafa","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy University of Lahore  Lahore Punjab Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0060-1693","authenticated-orcid":false,"given":"Mateen","family":"Elahi","sequence":"additional","affiliation":[{"name":"Department of Surgery Services Institute of Medical Sciences  Lahore Punjab Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin","family":"Elahi","sequence":"additional","affiliation":[{"name":"Department of Surgery Jinnah Hospital  Lahore Punjab Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kashif","family":"Barkat","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy University of Lahore  Lahore Punjab Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Umer","family":"Ashraf","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy University of Lahore  Lahore Punjab Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd Shahezwan Abd","family":"Wahab","sequence":"additional","affiliation":[{"name":"Elderly Medication and Safety Research Interest Group, Faculty of Pharmacy Universiti Teknologi MARA (UiTM) Cawangan Selangor  Puncak Alam Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6656-2063","authenticated-orcid":false,"given":"Sumera Saeed","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Primary Health Care, Faculty of Medicine University of Otago  Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/ajm.ajm_53_20"},{"key":"e_1_2_11_3_1","volume-title":"Type 2 Diabetes","author":"Goyal 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Diabetes Care: A Cross\u2010Sectional Study","volume":"2","author":"Hasan S. 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