{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T09:06:58Z","timestamp":1769764018145,"version":"3.49.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":3149,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Cardiac involvement in sarcoidosis is reported in up to 30% of patients. Left ventricular involvement demonstrated by contrast-enhanced cardiac magnetic resonance has been well validated. We sought to determine the prevalence and distribution of right ventricular late gadolinium enhancement in patients diagnosed with pulmonary sarcoidosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We prospectively evaluated 87 patients diagnosed with pulmonary sarcoidosis with contrast-enhanced cardiac magnetic resonance for right ventricular involvement. Pulmonary artery pressures were non-invasively evaluated with Doppler echocardiography. Patient characteristics were compared between the groups with and without right ventricular involvement, and right ventricular enhancement was correlated with pulmonary hypertension, ventricular mass, volume, and systolic function. Left ventricular late gadolinium enhancement was demonstrated in 30 patients (34%). Fourteen patients (16%) had right ventricular late gadolinium enhancement, with sole right ventricular enhancement in only two patients. The pattern of right ventricular enhancement consisted of right ventricular outflow tract enhancement in 1 patient, free wall enhancement in 8 patients, ventricular insertion point enhancement in 10 patients, and enhancement of the right side of the interventricular septum in 11 patients. Pulmonary arterial hypertension correlated with the presence of right ventricular enhancement (P &amp;lt; 0.001). Right ventricular enhancement correlated with systolic ventricular dysfunction (P &amp;lt; 0.001), hypertrophy (P = 0.001), and dilation (P &amp;lt; 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Right ventricular enhancement was present in 16% of patients diagnosed with pulmonary sarcoidosis and in 48% of patients with left ventricular enhancement. The presence of right ventricular enhancement correlated with pulmonary arterial hypertension, right ventricular systolic dysfunction, hypertrophy, and dilation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.12166","type":"journal-article","created":{"date-parts":[[2017,6,7]],"date-time":"2017-06-07T00:16:53Z","timestamp":1496794613000},"page":"535-544","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Right Ventricular Involvement in Cardiac Sarcoidosis Demonstrated with Cardiac Magnetic Resonance"],"prefix":"10.1093","volume":"4","author":[{"given":"Jan-Peter","family":"Smedema","sequence":"first","affiliation":[{"name":"Department of Cardiology, Maastricht University Medical Centre , Maastricht ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert-Jan","family":"van Geuns","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus Medical Centre , Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gillian","family":"Ainslie","sequence":"additional","affiliation":[{"name":"Respiratory Clinic, Department of Medicine, Groote Schuur Hospital , Cape Town ,","place":["South Africa"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joris","family":"Ector","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospitals Gasthuisberg , Leuven ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hein","family":"Heidbuchel","sequence":"additional","affiliation":[{"name":"University of Hasselt Heart Centre, Virga Jessa Hospital , Hasselt ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry J.G.M.","family":"Crijns","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Maastricht University Medical Centre , Maastricht ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"key":"2026012115152267800_ehf212166-bib-0001","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1136\/hrt.2011.226076","article-title":"Cardiac sarcoidosis: applications of imaging in diagnosis and directing treatment","volume":"97","author":"Youssef","year":"2011","journal-title":"Heart"},{"key":"2026012115152267800_ehf212166-bib-0002","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1016\/j.jacc.2005.01.047","article-title":"Evaluation of the accuracy of gadolinium-enhanced cardiovascular magnetic resonance in the diagnosis of cardiac sarcoidosis","volume":"45","author":"Smedema","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"2026012115152267800_ehf212166-bib-0003","doi-asserted-by":"crossref","DOI":"10.1186\/1532-429X-16-S1-P280","article-title":"Sarcoidosis; is it confined to just the LV? 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