{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T12:22:23Z","timestamp":1784809343582,"version":"3.55.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":2193,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T00:00:00Z","timestamp":1576627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Swedish Heart and Lung Foundation","award":["20130340"],"award-info":[{"award-number":["20130340"]}]},{"name":"Swedish Heart and Lung Foundation","award":["20160439"],"award-info":[{"award-number":["20160439"]}]},{"name":"Swedish Heart and Lung Foundation","award":["20160439"],"award-info":[{"award-number":["20160439"]}]},{"name":"Swedish Heart and Lung Foundation","award":["20130340"],"award-info":[{"award-number":["20130340"]}]},{"name":"Swedish National Science Council","award":["K2013-69X-22302-01-3"],"award-info":[{"award-number":["K2013-69X-22302-01-3"]}]},{"name":"Swedish National Science Council","award":["2016-01390"],"award-info":[{"award-number":["2016-01390"]}]},{"name":"Swedish National Science Council","award":["2016-01390"],"award-info":[{"award-number":["2016-01390"]}]},{"name":"Swedish National Science Council","award":["K2013-69X-22302-01-3"],"award-info":[{"award-number":["K2013-69X-22302-01-3"]}]},{"name":"Swedish National Science Council\/Swedish research council for health, working life and welfare","award":["2014-4100"],"award-info":[{"award-number":["2014-4100"]}]},{"DOI":"10.13039\/100009107","name":"V\u00e5rdal Foundation","doi-asserted-by":"publisher","award":["2014-0018"],"award-info":[{"award-number":["2014-0018"]}],"id":[{"id":"10.13039\/100009107","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009107","name":"V\u00e5rdal Foundation","doi-asserted-by":"publisher","award":["2014\u20130018"],"award-info":[{"award-number":["2014\u20130018"]}],"id":[{"id":"10.13039\/100009107","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010805","name":"Medical Research Council of Southeast Sweden","doi-asserted-by":"publisher","award":["FORSS 474681"],"award-info":[{"award-number":["FORSS 474681"]}],"id":[{"id":"10.13039\/100010805","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Swedish Heart and Lung Association","award":["E085\/12"],"award-info":[{"award-number":["E085\/12"]}]},{"name":"Swedish National Science Council\/Swedish Research Council for Health, Working Life and Welfare","award":["2014-4100"],"award-info":[{"award-number":["2014-4100"]}]},{"DOI":"10.13039\/100009107","name":"V\u00e5rdalstiftelsen","doi-asserted-by":"publisher","award":["2014\u20100018"],"award-info":[{"award-number":["2014\u20100018"]}],"id":[{"id":"10.13039\/100009107","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009107","name":"V\u00e5rdalstiftelsen","doi-asserted-by":"publisher","award":["2014\u20130018"],"award-info":[{"award-number":["2014\u20130018"]}],"id":[{"id":"10.13039\/100009107","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010805","name":"Forskningsr\u00e5det i Syd\u00f6stra Sverige","doi-asserted-by":"publisher","award":["FORSS 474681"],"award-info":[{"award-number":["FORSS 474681"]}],"id":[{"id":"10.13039\/100010805","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Cognitive impairment (CI) in heart failure (HF) patients has mostly been studied in single countries in specific health care settings. Sociodemographic and clinical predictors of the global CI and CI dimensions are still unclear. We described CI in a diverse HF population recruited in several countries and in different health care settings and investigated sociodemographic and clinical factors associated with the global and specific CI dimensions in HF patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>A secondary analysis from the baseline data of the Wii-HF trial. Patients (n = 605) were enrolled in Sweden, Italy, Israel, The Netherlands, Germany, and the United States. We used the Montreal Cognitive Assessment to evaluate CI and the 6 minute walk test (6MWT) to measure exercise capacity. Patients were on average 67 years old (SD, 12), and 86% were in New York Heart Association Class II and III. The mean Montreal Cognitive Assessment score was 24 (SD, 4), and 67% of patients had at least a mild CI. The item evaluating short-term memory had a considerable proportion of low scoring patients (28.1%). Worse CI was associated with patients' older age, lower education, and lower 6MWT scores (R2 = 0.27). CI dimension scores were differently associated with specific clinical and demographic variables, but the 6MWT scores were associated with five out of seven CI dimension scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CI is an important problem in HF patients, with specific challenges in regard to memory. Exercise capacity is a modifiable factor that could be improved in HF patients with the potential to improve cognition and other outcomes in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.12542","type":"journal-article","created":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T00:55:00Z","timestamp":1576716900000},"page":"47-54","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Cognitive Impairment in Patients with Heart Failure: An International Study"],"prefix":"10.1093","volume":"7","author":[{"given":"Ercole","family":"Vellone","sequence":"first","affiliation":[{"name":"Department of Biomedicine and Prevention, University of Rome Tor Vergata , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oronzo","family":"Chial\u00e0","sequence":"additional","affiliation":[{"name":"Department of Biomedicine and Prevention, University of Rome Tor Vergata , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josiane","family":"Boyne","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Maastricht University Medical Centre , Maastricht ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonie","family":"Klompstra","sequence":"additional","affiliation":[{"name":"Department of Social and Welfare Studies, Faculty of Health Science, Link\u00f6ping University , Link\u00f6ping ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine S.","family":"Evangelista","sequence":"additional","affiliation":[{"name":"Sue & Bill Gross School of Nursing, University of California Irvine , Irvine, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Back","sequence":"additional","affiliation":[{"name":"Division of Physiotherapy, Department of Medical and Health Sciences, Link\u00f6ping University , Link\u00f6ping ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuvia","family":"Ben Gal","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rabin Medical Center (Beilinson Campus) , Petah Tikva ,","place":["Israel"]},{"name":"Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"M\u00e5rtensson","sequence":"additional","affiliation":[{"name":"Department of Nursing, School of Health and Welfare, J\u00f6nk\u00f6ping University , J\u00f6nk\u00f6ping ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Str\u00f6mberg","sequence":"additional","affiliation":[{"name":"Division of Physiotherapy, Department of Medical and Health Sciences, Link\u00f6ping University , Link\u00f6ping ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiny","family":"Jaarsma","sequence":"additional","affiliation":[{"name":"Department of Social and Welfare Studies, Faculty of Health Science, Link\u00f6ping University , Link\u00f6ping ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,12,18]]},"reference":[{"key":"2026012115055097300_ehf212542-bib-0001","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"37","author":"Ponikowski","year":"2016","journal-title":"Eur Heart J."},{"key":"2026012115055097300_ehf212542-bib-0002","article-title":"2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"62","author":"Yancy","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"2026012115055097300_ehf212542-bib-0003","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1097\/JCN.0000000000000493","article-title":"Changes in heart failure symptoms are associated with changes in health-related quality of life over 12 months in patients with heart failure","volume":"33","author":"Heo","year":"2018","journal-title":"J Cardiovasc Nurs"},{"key":"2026012115055097300_ehf212542-bib-0004","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.recesp.2018.05.037","article-title":"Population-based study of first hospitalizations for heart failure and the interaction between readmissions and survival","volume":"72","author":"Fern\u00e1ndez-Gass\u00f3","year":"2018","journal-title":"Rev Espa\u00f1ola Cardiol (English Ed.)"},{"key":"2026012115055097300_ehf212542-bib-0005","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/ggi.13580","article-title":"Sex differences in 1-year mortality risks in older patients experiencing a first acute heart failure hospitalization","volume":"19","author":"Formiga","year":"2019","journal-title":"Geriatr Gerontol Int"},{"key":"2026012115055097300_ehf212542-bib-0006","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1186\/s12889-018-6034-0","article-title":"Indirect costs and public finance consequences of heart failure in Poland, 2012\u20132015","volume":"18","author":"\u0141yszczarz","year":"2018","journal-title":"BMC Public Health"},{"key":"2026012115055097300_ehf212542-bib-0007","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.cardfail.2018.12.006","article-title":"The prevalence of cognitive impairment among adults with incident heart failure: the reasons for geographic and racial differences in stroke (REGARDS) study","volume":"25","author":"Sterling","year":"2018","journal-title":"J Card Fail"},{"key":"2026012115055097300_ehf212542-bib-0008","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.cardfail.2017.04.007","article-title":"Cognitive impairment and heart failure: systematic review and meta-analysis","volume":"23","author":"Cannon","year":"2017","journal-title":"J Card Fail"},{"key":"2026012115055097300_ehf212542-bib-0009","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.ijcard.2016.07.074","article-title":"Mild cognitive impairment predicts death and readmission within 30 days of discharge for heart failure","volume":"221","author":"Huynh","year":"2016","journal-title":"Int J Cardiol"},{"key":"2026012115055097300_ehf212542-bib-0010","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ijcard.2014.10.087","article-title":"Heart failure and cognitive dysfunction","volume":"178","author":"Ampadu","year":"2015","journal-title":"Int J Cardiol"},{"key":"2026012115055097300_ehf212542-bib-0011","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1161\/CIRCOUTCOMES.115.001856","article-title":"Incidence and predictors of cognitive decline in patients with left ventricular assist devices","volume":"8","author":"Fendler","year":"2015","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"2026012115055097300_ehf212542-bib-0012","doi-asserted-by":"crossref","first-page":"34","DOI":"10.5812\/nms.12442","article-title":"The study of cognitive function and related factors in patients with heart failure","volume":"2","author":"Ghanbari","year":"2013","journal-title":"Nurs midwifery Stud"},{"key":"2026012115055097300_ehf212542-bib-0013","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.cardfail.2014.12.010","article-title":"Decreases in daily physical activity predict acute decline in attention and executive function in heart failure","volume":"21","author":"Alosco","year":"2015","journal-title":"J Card Fail"},{"key":"2026012115055097300_ehf212542-bib-0014","doi-asserted-by":"crossref","first-page":"481","DOI":"10.2459\/JCM.0000000000000005","article-title":"Chronic renal dysfunction and anaemia are associated with cognitive impairment in older patients with heart failure","volume":"15","author":"Pulignano","year":"2014","journal-title":"J Cardiovasc Med"},{"key":"2026012115055097300_ehf212542-bib-0015","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.amjcard.2013.12.032","article-title":"Prevalence of memory disorders in ambulatory patients aged &gt;\/=70 years with chronic heart failure (from the EFICARE study)","volume":"113","author":"Hanon","year":"2014","journal-title":"Am J Cardiol"},{"key":"2026012115055097300_ehf212542-bib-0016","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/ejhf.305","article-title":"Increasing exercise capacity and quality of life of patients with heart failure through Wii gaming: the rationale, design and methodology of the HF-Wii study; a multicentre randomized controlled trial","volume":"17","author":"Jaarsma","year":"2015","journal-title":"Eur J Heart Fail"},{"key":"2026012115055097300_ehf212542-bib-0017","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal cognitive assessment, MoCA: a brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"2026012115055097300_ehf212542-bib-0018","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.hrtlng.2010.11.002","article-title":"Montreal cognitive assessment and mini-mental status examination compared as cognitive screening tools in heart failure","volume":"40","author":"Athilingam","year":"2011","journal-title":"Hear Lung"},{"key":"2026012115055097300_ehf212542-bib-0019","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"key":"2026012115055097300_ehf212542-bib-0020","first-page":"919","article-title":"The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure","volume":"132","author":"Guyatt","year":"1985","journal-title":"Can Med Assoc J"},{"key":"2026012115055097300_ehf212542-bib-0021","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S1388-9842(02)00244-1","article-title":"Prognostic value of 6-minute walk corridor test in patients with mild to moderate heart failure: comparison with other methods of functional evaluation","volume":"5","author":"Rostagno","year":"2003","journal-title":"Eur J Heart Fail"},{"key":"2026012115055097300_ehf212542-bib-0022","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.hrtlng.2014.12.003","article-title":"The association between cognitive function and self-care in patients with chronic heart failure","volume":"44","author":"Hjelm","year":"2015","journal-title":"Hear Lung J Acute Crit Care"},{"key":"2026012115055097300_ehf212542-bib-0023","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.amjcard.2010.12.021","article-title":"Screening for cognitive deficits using the Montreal cognitive assessment tool in outpatients \u226565 years of age with heart failure","volume":"107","author":"Harkness","year":"2011","journal-title":"Am J Cardiol"},{"key":"2026012115055097300_ehf212542-bib-0024","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.cardfail.2013.08.001","article-title":"Mild cognitive impairment, screening, and patient perceptions in heart failure patients","volume":"19","author":"Gallagher","year":"2013","journal-title":"J Card Fail"},{"key":"2026012115055097300_ehf212542-bib-0025","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.hrtlng.2017.09.005","article-title":"Memory loss and decreased executive function are associated with limited functional capacity in patients with heart failure compared to patients with other medical conditions","volume":"47","author":"Kim","year":"2018","journal-title":"Heart Lung"},{"key":"2026012115055097300_ehf212542-bib-0026","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1017\/S1355617715000697","article-title":"Daily physical activity is associated with subcortical brain volume and cognition in heart failure","volume":"21","author":"Alosco","year":"2015","journal-title":"J Int Neuropsychol Soc"},{"key":"2026012115055097300_ehf212542-bib-0027","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.hrtlng.2018.06.008","article-title":"Cognitive impairment predicts mortality in outpatient veterans with heart failure","volume":"47","author":"Lan","year":"2018","journal-title":"Hear Lung"},{"key":"2026012115055097300_ehf212542-bib-0028","doi-asserted-by":"crossref","first-page":"145","DOI":"10.12788\/jhm.2932","article-title":"Numeracy, health literacy, cognition, and 30-day readmissions among patients with heart failure","volume":"13","author":"Sterling","year":"2018","journal-title":"J Hosp Med"},{"key":"2026012115055097300_ehf212542-bib-0029","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.jagp.2019.01.211","article-title":"Exercise and cognitive training as a strategy to improve neurocognitive outcomes in heart failure: a pilot study","volume":"27","author":"Gary","year":"2019","journal-title":"Am J Geriatr Psychiatry."}],"container-title":["ESC Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fehf2.12542","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ehf2.12542","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ehf2.12542","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/eschf\/article-pdf\/7\/1\/47\/65804257\/eschf_7_1_47.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eschf\/article-pdf\/7\/1\/47\/65804257\/eschf_7_1_47.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T20:07:05Z","timestamp":1769026025000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eschf\/article\/7\/1\/47\/8373170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,18]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,12,18]]},"published-print":{"date-parts":[[2020,2,1]]}},"URL":"https:\/\/doi.org\/10.1002\/ehf2.12542","relation":{},"ISSN":["2055-5822"],"issn-type":[{"value":"2055-5822","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,2]]},"published":{"date-parts":[[2019,12,18]]},"assertion":[{"value":"2019-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}