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All participants were successfully matched 1:1 with controls from the general population on age, sex, and hypertension. Mean age of the study sample was 69 years, and 55% were male participants. LV and RV systolic function was significantly reduced in COVID-19 cases as assessed by global longitudinal strain (GLS) (16.4% \u00b1 4.3 vs. 18.5% \u00b1 3.0, P &amp;lt; 0.001), tricuspid annular plane systolic excursion (TAPSE) (2.0 \u00b1 0.4 vs. 2.6 \u00b1 0.5, P &amp;lt; 0.001), and RV strain (19.8 \u00b1 5.9 vs. 24.2 \u00b1 6.5, P = 0.004). All parameters remained significantly reduced after adjusting for important cardiac risk factors. During follow-up (median: 40 days), 25 COVID-19 cases died. In multivariable Cox regression reduced TAPSE [hazard ratio (HR) = 1.18, 95% confidence interval (CI) [1.07\u20131.31], P = 0.002, per 1 mm decrease], RV strain (HR = 1.64, 95%CI[1.02;2.66], P = 0.043, per 1% decrease) and GLS (HR = 1.20, 95%CI[1.07\u20131.35], P = 0.002, per 1% decrease) were significantly associated with COVID-19-related death. TAPSE and GLS remained significantly associated with the outcome after restricting the analysis to patients without prevalent heart disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>RV and LV function are significantly impaired in hospitalized COVID-19 patients compared with matched controls. Furthermore, reduced TAPSE and GLS are independently associated with COVID-19-related death.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.13044","type":"journal-article","created":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T10:51:42Z","timestamp":1603363902000},"page":"4189-4197","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":89,"title":["Echocardiographic Abnormalities and Predictors of Mortality in Hospitalized COVID-19 Patients: The ECHOVID-19 Study"],"prefix":"10.1093","volume":"7","author":[{"given":"Mats Christian H\u00f8jbjerg","family":"Lassen","sequence":"first","affiliation":[{"name":"Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen , Copenhagen ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristoffer Grundtvig","family":"Skaarup","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Herlev & 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