{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T04:33:56Z","timestamp":1784176436096,"version":"3.55.0"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T00:00:00Z","timestamp":1766188800000},"content-version":"vor","delay-in-days":1828,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T00:00:00Z","timestamp":1608249600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Because reported mortality on veno-arterial (V-A) extracorporeal life support (ECLS) substantially varies between centres, the aim of the current analysis was to assess the outcomes between units performing heart transplantation and\/or implanting ventricular assist device (HTx\/VAD) vs. non-HTx\/VAD units in patients undergoing V-A ECLS for cardiogenic shock.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Systematic search according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses was performed using PubMed\/MEDLINE databases until 30 November 2019. Articles reporting in-hospital\/30-day mortality and centre's HTx\/VAD status were included. In-hospital outcomes and long-term survival were analysed in subgroup meta-analysis. A total of 174 studies enrolling n = 13 308 patients were included with 20 series performed in non-HTx\/VAD centres (1016 patients, 7.8%). Majority of patients underwent V-A ECLS for post-cardiotomy shock (44.2%) and acute myocardial infarction (20.7%). Estimated overall in-hospital mortality was 57.2% (54.9\u201359.4%). Mortality rates were higher in non-HTx\/VAD [65.5% (59.8\u201370.8%)] as compared with HTx\/VAD centres [55.8% (53.3\u201358.2%)], P &amp;lt; 0.001. Estimated late survival was 61.8% (55.7\u201367.9%) without differences between non-HTx\/VAD and HTx\/VAD centres: 66.5% (30.3\u20131.02%) vs. 61.7% (55.5\u201367.8%), respectively (P = 0.797). No differences were seen with respect to ECLS duration, limb complications, and reoperations for bleeding, kidney injury, and sepsis. Yet, weaning rates were higher in HTx\/VAD vs. non-HTx\/VAD centres: 58.7% (56.2\u201361.1%) vs. 48.9% (42.0\u201355.9%), P = 0.010. Estimated rate of bridge to heart transplant was 6.6% (5.2\u20138.3%) with numerical, yet not statistically significant, difference between non-HTx\/VAD [2.7% (0.8\u20138.3%)] as compared with HTx\/VAD [6.7% (5.3\u20138.6%)] (P = 0.131).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Survival after V-A ECLS differed according to centre's HTx\/VAD status. Potentially different risk profiles of patients must be taken account for before definite conclusions are drawn.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.13080","type":"journal-article","created":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T12:31:23Z","timestamp":1608294683000},"page":"1064-1075","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Veno-Arterial Extracorporeal Life Support in Heart Transplant and Ventricle Assist Device Centres. Meta-Analysis"],"prefix":"10.1093","volume":"8","author":[{"given":"Mariusz","family":"Kowalewski","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Central Clinical Hospital of the Ministry of Interior, Centre of Postgraduate Medical Education , Wo\u0142oska 137 Str, Warsaw, 02-507 ,","place":["Poland"]},{"name":"Cardio-Thoracic Surgery Department, Maastricht University Medical Centre , Maastricht ,","place":["The Netherlands"]},{"name":"Thoracic Research Centre, Collegium Medicum, Nicolaus Copernicus University, Innovative Medical Forum , Bydgoszcz ,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Zieli\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical University of Warsaw , Warsaw ,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miros\u0142aw","family":"Gozdek","sequence":"additional","affiliation":[{"name":"Thoracic Research Centre, Collegium Medicum, Nicolaus Copernicus University, Innovative Medical Forum , Bydgoszcz ,","place":["Poland"]},{"name":"Department of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University , Bydgoszcz ,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Maria","family":"Raffa","sequence":"additional","affiliation":[{"name":"Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, ISMETT-IRCCS , Palermo ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Pilato","sequence":"additional","affiliation":[{"name":"Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, ISMETT-IRCCS , Palermo ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musab","family":"Alanazi","sequence":"additional","affiliation":[{"name":"Cardio-Thoracic Surgery 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