{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T06:18:10Z","timestamp":1784614690117,"version":"3.55.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T00:00:00Z","timestamp":1766188800000},"content-version":"vor","delay-in-days":1799,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,1,16]],"date-time":"2021-01-16T00:00:00Z","timestamp":1610755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>In peripartum cardiomyopathy (PPCM), electrocardiography (ECG) and its relationship to echocardiography have not yet been investigated in large multi-centre and multi-ethnic studies. We aimed to identify ECG abnormalities associated with PPCM, including regional and ethnic differences, and their correlation with echocardiographic features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We studied 411 patients from the EURObservational PPCM registry. Baseline demographic, clinical, and echocardiographic data were collected. ECGs were analysed for rate, rhythm, QRS width and morphology, and QTc interval. The median age was 31 [interquartile range (IQR) 26\u201335] years. The ECG was abnormal in &amp;gt; 95% of PPCM patients. Sinus tachycardia (heart rate &amp;gt; 100 b.p.m.) was common (51%), but atrial fibrillation was rare (2.27%). Median QRS width was 82 ms [IQR 80\u201397]. Left bundle branch block (LBBB) was reported in 9.30%. Left ventricular (LV) hypertrophy (LVH), as per ECG criteria, was more prevalent amongst Africans (59.62%) and Asians (23.17%) than Caucasians (7.63%, P &amp;lt; 0.001) but did not correlate with LVH on echocardiography. Median LV end-diastolic diameter (LVEDD) was 60 mm [IQR 55\u201365] and LV ejection fraction (LVEF) 32.5% [IQR 25\u201339], with no significant regional or ethnic differences. Sinus tachycardia was associated with an LVEF &amp;lt; 35% (OR 1.85 [95% CI 1.20\u20132.85], P = 0.006). ECG features that predicted an LVEDD &amp;gt; 55 mm included a QRS complex &amp;gt; 120 ms (OR 11.32 [95% CI 1.52\u201384.84], P = 0.018), LBBB (OR 4.35 [95% CI 1.30\u201314.53], P = 0.017), and LVH (OR 2.03 [95% CI 1.13\u20133.64], P = 0.017).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PPCM patients often have ECG abnormalities. Sinus tachycardia predicted poor systolic function, whereas wide QRS, LBBB, and LVH were associated with LV dilatation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.13172","type":"journal-article","created":{"date-parts":[[2021,1,16]],"date-time":"2021-01-16T11:40:35Z","timestamp":1610797235000},"page":"879-889","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Electrocardiographic Features and their Echocardiographic Correlates in Peripartum Cardiomyopathy: Results from the ESC EORP PPCM Registry"],"prefix":"10.1093","volume":"8","author":[{"given":"Amam C.","family":"Mbakwem","sequence":"first","affiliation":[{"name":"Department of Medicine, College of Medicine, University of Lagos , Idi Araba, Lagos ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"Bauersachs","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Hannover Medical School , Hannover ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charle","family":"Viljoen","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, University of Cape Town , Cape Town ,","place":["South Africa"]},{"name":"Hatter Institute for Cardiovascular Research in Africa and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town , Cape Town ,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Hoevelmann","sequence":"additional","affiliation":[{"name":"Hatter Institute for Cardiovascular Research in Africa and Cape Heart Institute, Faculty of Health Sciences, University of Cape Town , Cape Town ,","place":["South Africa"]},{"name":"Klinik f\u00fcr Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universit\u00e4tsklinikum des Saarlandes, Saarland University Hospital , Homburg\/Saar ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"van der Meer","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center Groningen, University of Groningen , Groningen ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark C.","family":"Petrie","sequence":"additional","affiliation":[{"name":"Institute of Cardiovascular & Medical Sciences, University of Glasgow , Glasgow ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Mebazaa","sequence":"additional","affiliation":[{"name":"UMR 942 Inserm \u2013 MASCOT; University of Paris; Department of Anesthesia-Burn-Critical Care, APHP Saint Louis Lariboisi\u00e8re University Hospitals , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorel","family":"Goland","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hebrew University and Hadassah Medical School , Jerusalem ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamilu","family":"Karaye","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bayero University , Kano ,","place":["Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Laroche","sequence":"additional","affiliation":[{"name":"ESC, EURObservational Research Programme , Sophia-Antipolis ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Sliwa","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, University of Cape Town , Cape Town ,","place":["South Africa"]},{"name":"Hatter Institute for Cardiovascular 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