{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:30:48Z","timestamp":1790721048242,"version":"4.1.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T00:00:00Z","timestamp":1766188800000},"content-version":"vor","delay-in-days":1631,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T00:00:00Z","timestamp":1625270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011102","name":"European Union Seventh Framework Programme","doi-asserted-by":"publisher","award":["241558"],"award-info":[{"award-number":["241558"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["241558"],"award-info":[{"award-number":["241558"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cachexia is common in patients with chronic heart failure and is associated with poor prognosis. How best to measure body composition is not clear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We characterized body composition in 120 patients with chronic heart failure: mean (SD) age 70 (10) years, left ventricular ejection fraction 44 (10) %, and median (Q1\u2013Q3) N-terminal pro B-type natriuretic peptide 845 (355\u20131368) ng\/L. We measured body composition using dual-energy X-ray absorptiometry (DEXA) and a multi-frequency bioelectrical impedance analysis (BIA) device (Tanita BIA MC-180MA). Mean (SD) fat mass (FM) was 27.2 (11.7) kg by BIA and 32.3 (12.2) kg by DEXA (mean difference \u22125.1 kg, 95% limits of agreement: \u221211.7, 1.5; 4% of values outside limit of agreement); mean (SD) lean mass (LM) was 56.6 (10.9) kg by BIA and 51.1 (9.9) kg by DEXA (mean difference 5.5 kg, 95% limits of agreement: \u22121.3, 12.3; 6% of values outside limit of agreement); and mean (SD) bone mass (BM) was 3.0 (0.5) kg by BIA and 2.8 (0.6) kg by DEXA (mean difference 0.2 kg, 95% limits of agreement: \u22120.5, 0.8; 5% of values outside limit of agreement). There was a close correlation between DEXA and BIA for both LM and FM (LM: r = 0.95, P &amp;lt; 0.001; FM: r = 0.96, P &amp;lt; 0.001) but less so for BM (r = 0.84, P &amp;lt; 0.001). Both DEXA and BIA body composition measurements correlated well with other measures of body size (body mass index, hip circumference, and waist circumference).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There are differences in the measurements of FM, LM, and BM between the two techniques, which should not be used interchangeably.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.13402","type":"journal-article","created":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T04:46:16Z","timestamp":1625287576000},"page":"3929-3934","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["A Comparison of Non-Invasive Methods of Measuring Body Composition in Patients with Heart Failure: A Report from SICA-HF"],"prefix":"10.1093","volume":"8","author":[{"given":"Parin","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Cottingham, Kingston upon Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra A.I.","family":"Abel","sequence":"additional","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Cottingham, Kingston upon Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vennela","family":"Boyalla","sequence":"additional","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Cottingham, Kingston upon Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo","family":"Pellicori","sequence":"additional","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Cottingham, Kingston upon Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Kallvikbacka-Bennett","sequence":"additional","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Cottingham, Kingston upon Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"Sze","sequence":"additional","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Cottingham, Kingston upon Hull, HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.F.","family":"Cleland","sequence":"additional","affiliation":[{"name":"Robertson Centre for Biostatistics, University of Glasgow , Glasgow ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew L.","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Cottingham, Kingston upon 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