{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T09:34:14Z","timestamp":1774085654208,"version":"3.50.1"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T00:00:00Z","timestamp":1766188800000},"content-version":"vor","delay-in-days":1632,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T00:00:00Z","timestamp":1625184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"German Heart Foundation\/German Foundation of Heart Research"},{"DOI":"10.13039\/501100010441","name":"Faculty of Medicine, University of Heidelberg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010441","id-type":"DOI","asserted-by":"publisher"}]},{"name":"German Society of Internal Medicine"},{"DOI":"10.13039\/501100010441","name":"Medizinischen Fakult\u00e4t Heidelberg, Universit\u00e4t Heidelberg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010441","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Right bundle branch block (RBBB) after heart transplantation (HTX) is a common finding, but its impact on post-transplant survival remains uncertain. This study investigated the post-transplant outcomes of patients with complete RBBB (cRBBB) \u2264 30 days after HTX.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This registry study analysed 639 patients receiving HTX at Heidelberg Heart Center between 1989 and 2019. Patients were stratified by diagnosis of cRBBB \u2264 30 days after HTX. Analysis included recipient and donor data, medication, echocardiographic features, graft rejections, atrial fibrillation, heart rates, permanent pacemaker implantation and mortality after HTX including causes of death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One hundred thirty-nine patients showed cRBBB \u2264 30 days after HTX (21.8%), 20 patients with pre-existing cRBBB in the donor heart (3.2%) and 119 patients with newly acquired cRBBB (18.6%). Patients with newly acquired cRBBB had a worse 1-year post-transplant survival (36.1%, P &amp;lt; 0.01) compared with patients with pre-existing cRBBB (85.0%) or without cRBBB (86.4%), along with a higher percentage of death due to graft failure (P &amp;lt; 0.01). Multivariate analysis indicated cRBBB \u2264 30 days after HTX as significant risk factor for 1-year mortality after HTX (HR: 2.20; 95% CI: 1.68\u20132.87; P &amp;lt; 0.01). Secondary outcomes showed a higher rate of an enlarged right atrium (P = 0.01), enlarged right ventricle (P &amp;lt; 0.01), reduced right ventricular function (P &amp;lt; 0.01), 30-day atrial fibrillation (P &amp;lt; 0.01) and 1-year permanent pacemaker implantation (P = 0.02) in patients with cRBBB after HTX.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Newly acquired cRBBB early after HTX is associated with increased post-transplant mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.13494","type":"journal-article","created":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T06:44:37Z","timestamp":1625208277000},"page":"3737-3747","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Newly Acquired Complete Right Bundle Branch Block Early After Heart Transplantation is Associated with Lower Survival"],"prefix":"10.1093","volume":"8","author":[{"given":"Ann-Kathrin","family":"Rahm","sequence":"first","affiliation":[{"name":"Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"Heidelberg Center for Heart Rhythm Disorders (HCR), Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg\/Mannheim , Heidelberg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Helmschrott","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg\/Mannheim , Heidelberg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrice F.","family":"Darche","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"Heidelberg Center for Heart Rhythm Disorders (HCR), Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg\/Mannheim , Heidelberg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dierk","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"Heidelberg Center for Heart Rhythm Disorders (HCR), Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg\/Mannheim , Heidelberg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Bruckner","sequence":"additional","affiliation":[{"name":"Institute for Medical Biometry and Informatics, University of Heidelberg , Heidelberg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Ehlermann","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg\/Mannheim , Heidelberg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael M.","family":"Kreusser","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg\/Mannheim , Heidelberg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregor","family":"Warnecke","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Frey","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"Heidelberg Center for Heart Rhythm Disorders (HCR), Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg\/Mannheim , Heidelberg 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