{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T20:55:39Z","timestamp":1789419339537,"version":"build-2803163510"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T00:00:00Z","timestamp":1764892800000},"content-version":"vor","delay-in-days":1439,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T00:00:00Z","timestamp":1640563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Tachycardia and rapid tachyarrhythmias are common in acute clinical settings and may hasten the deterioration of haemodynamics in patients with acute decompensated heart failure (ADHF), treated with inotropes. The concomitant use of a short-acting \u03b21-selective beta-blocker, such as landiolol, could rapidly and safely restore an adequate heart rate without any negative inotropic effect. We present a case series of five patients with left ventricular dysfunction, admitted to our Intensive Cardiac Care Unit with ADHF deteriorated to cardiogenic shock, treated with a combination of landiolol and inotropes. Landiolol was effective in terms of rate control and haemodynamics optimization, enabling de-escalation of catecholamine dosing in all patients. The infusion was always well tolerated without hypotension. In conclusion, a continuous infusion of a low dose of landiolol (3\u201316 mcg\/kg\/min) to manage tachycardia and ventricular or supraventricular tachyarrhythmias in haemodynamically unstable patients may be considered.<\/jats:p>","DOI":"10.1002\/ehf2.13763","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T01:41:25Z","timestamp":1640655685000},"page":"766-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Effect of Landiolol in Patients with Tachyarrhythmias and Acute Decompensated Heart Failure (ADHF): A Case Series"],"prefix":"10.1093","volume":"9","author":[{"given":"Valentina","family":"Ditali","sequence":"first","affiliation":[{"name":"School of Medicine and Surgery, University of Pavia , Pavia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1863-1874","authenticated-orcid":false,"given":"Laura","family":"Garatti","sequence":"additional","affiliation":[{"name":"Department of Cardiology De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda , Milan ,","place":["Italy"]},{"name":"School of Medicine and Surgery, University of Milano Bicocca , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuccia","family":"Morici","sequence":"additional","affiliation":[{"name":"Department of Cardiology De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Villanova","sequence":"additional","affiliation":[{"name":"Department of Cardiology De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Colombo","sequence":"additional","affiliation":[{"name":"Department of Cardiology De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Oliva","sequence":"additional","affiliation":[{"name":"Department of Cardiology De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Sacco","sequence":"additional","affiliation":[{"name":"Department of Cardiology De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,12,27]]},"reference":[{"key":"2026012114181148400_ehf213763-bib-0001","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/j.1540-8159.2005.00143.x","article-title":"Tachycardia-induced cardiomyopathy: a review of literature","volume":"28","author":"Khasnis","year":"2005","journal-title":"Pacing Clin Electrophysiol"},{"key":"2026012114181148400_ehf213763-bib-0002","doi-asserted-by":"crossref","first-page":"111","DOI":"10.2147\/VHRM.S210561","article-title":"Evaluating the therapeutic efficacy and safety of landiolol hydrochloride for management of arrhythmia in critical settings: review of the literature","volume":"16","author":"Matsuishi","year":"2020","journal-title":"Vasc Health Risk Manag"},{"key":"2026012114181148400_ehf213763-bib-0003","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1007\/s00134-014-3525-z","article-title":"Consensus on circulatory shock and hemodynamic monitoring. 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