{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:20:31Z","timestamp":1791505231911,"version":"4.3.4"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T00:00:00Z","timestamp":1764892800000},"content-version":"vor","delay-in-days":1351,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T00:00:00Z","timestamp":1648166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science","award":["20K08476"],"award-info":[{"award-number":["20K08476"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To clarify the usefulness of left atrial (LA) function and left ventricular (LV) function obtained by two-dimensional (2D) speckle tracking echocardiography to diagnose concomitant transthyretin amyloid cardiomyopathy (ATTR-CM) in patients with aortic stenosis (AS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We analysed 72 consecutive patients with moderate to severe AS who underwent 99mTc-pyrophosphate (PYP) scintigraphy at Kumamoto University Hospital from January 2012 to September 2020. We divided these 72 patients into 2 groups based on their 99mTc-PYP scintigraphy positivity or negativity. Among 72 patients, 16 patients (22%) were positive, and 56 patients (78%) were negative for 99mTc-PYP scintigraphy. In clinical baseline characteristics, natural logarithm troponin T was significantly higher in the 99mTc-PYP scintigraphy-positive than scintigraphy-negative group (\u22122.9 \u00b1 0.5 vs. \u22123.5 \u00b1 0.8 ng\/mL, P &amp;lt; 0.05). In conventional echocardiography, the severity of AS was not significantly different between these two groups. In 2D speckle tracking echocardiography, the relative apical longitudinal strain (LS) index (RapLSI) [apical LS\/ (basal LS + mid LS)] was significantly higher (1.09 \u00b1 0.49 vs. 0.78 \u00b1 0.23, P &amp;lt; 0.05) and the peak longitudinal strain rate (LSR) in LA was significantly lower in the 99mTc-PYP scintigraphy-positive than scintigraphy-negative group (0.36 \u00b1 0.14 vs. 0.55 \u00b1 0.20 s\u22121, P &amp;lt; 0.05). Multivariable logistic analysis revealed the peak LSR in LA and RapLSI were significantly associated with 99mTc-PYP scintigraphy positivity. Receiver operating characteristic analysis showed that the area under the curve (AUC) of the peak LSR in LA for 99mTc-PYP scintigraphy positivity was 0.79 and that the best cut-off value of the peak LSR in LA was 0.47 s\u22121 (sensitivity: 78.6% and specificity: 72.3%). The AUC of RapLSI for 99mTc-PYP scintigraphy positivity was 0.69, and the cut-off value of RapLSI was decided as 1.00 (sensitivity: 43.8% and specificity: 87.5%) according to the previous report. The 99mTc-PYP scintigraphy positivity in patients with RapLSI \u2265 1.0 and the peak LSR in LA \u2264 0.47 s\u22121 was 83.3% (5\/6), and the 99mTc-PYP scintigraphy negativity in patients with RapLSI &amp;lt; 1.0 and the peak LSR in LA &amp;gt; 0.47 s\u22121 was 96.6% (28\/29).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Left atrial and LV strain analysis were significantly associated with 99mTc-PYP scintigraphy positivity in ATTR-CM patients with moderate to severe AS. The combination of the peak LSR in LA and RapLSI might be a useful predictor of the presence of ATTR-CM in patients with moderate to severe AS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.13909","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T22:39:09Z","timestamp":1648247949000},"page":"1976-1986","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Utility of Left Atrial and Ventricular Strain for Diagnosis of Transthyretin Amyloid Cardiomyopathy in Aortic Stenosis"],"prefix":"10.1093","volume":"9","author":[{"given":"Fumi","family":"Oike","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Usuku","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]},{"name":"Department of Laboratory Medicine, Kumamoto University Hospital , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiichiro","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyohei","family":"Marume","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiji","family":"Takashio","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanobu","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Tabata","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Fujisue","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenshi","family":"Yamanaga","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Sueta","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinsuke","family":"Hanatani","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichiro","family":"Arima","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Araki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seitaro","family":"Oda","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Kawano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Soejima","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuharu","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medical Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiro","family":"Fukui","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Graduate School of Medical Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Tsujita","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556 ,","place":["Japan"]},{"name":"Center of Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University , Kumamoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,3,25]]},"reference":[{"key":"2026012114231291400_ehf213909-bib-0001","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0195-668X(03)00201-X","article-title":"A prospective survey of patients with valvular heart disease in Europe: the euro heart survey on valvular heart disease","volume":"24","author":"Iung","year":"2003","journal-title":"Eur Heart J"},{"key":"2026012114231291400_ehf213909-bib-0002","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/s12968-017-0415-x","article-title":"Cardiac amyloidosis is prevalent in older patients with aortic stenosis and carries worse prognosis","volume":"19","author":"Cavalcante","year":"2017","journal-title":"J Cardiovasc Magn Reson"},{"key":"2026012114231291400_ehf213909-bib-0003","first-page":"1128","article-title":"Left atrial structure and function in cardiac amyloidosis","volume":"18","author":"Nochioka","year":"2017","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026012114231291400_ehf213909-bib-0004","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1161\/CIRCULATIONAHA.116.021612","article-title":"Nonbiopsy diagnosis of cardiac transthyretin amyloidosis","volume":"133","author":"Gillmore","year":"2016","journal-title":"Circulation"},{"key":"2026012114231291400_ehf213909-bib-0005","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1002\/ehf2.13693","article-title":"99mTechnetium-pyrophosphate scintigraphy: a practical guide for early diagnosis of transthyretin amyloid cardiomyopathy","volume":"9","author":"Tahara","year":"2022","journal-title":"ESC Heart Failure"},{"key":"2026012114231291400_ehf213909-bib-0006","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1001\/jamacardio.2016.2839","article-title":"Multicenter study of planar technetium 99m pyrophosphate cardiac imaging: predicting survival for patients with ATTR cardiac amyloidosis","volume":"1","author":"Castano","year":"2016","journal-title":"JAMA Cardiol"},{"key":"2026012114231291400_ehf213909-bib-0007","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.cardfail.2019.08.001","article-title":"ASNC\/AHA\/ASE\/EANM\/HFSA\/ISA\/SCMR\/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: part 1 of 2\u2014evidence base and standardized methods of imaging","volume":"25","author":"Dorbala","year":"2019","journal-title":"J Card Fail"},{"key":"2026012114231291400_ehf213909-bib-0008","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1161\/CIRCIMAGING.113.000683","article-title":"Effect of combined systolic and diastolic functional parameter assessment for differentiation of cardiac amyloidosis from other causes of concentric left ventricular hypertrophy","volume":"6","author":"Liu","year":"2013","journal-title":"Circ Cardiovasc Imaging"},{"key":"2026012114231291400_ehf213909-bib-0009","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"key":"2026012114231291400_ehf213909-bib-0010","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/0002-9149(86)90771-X","article-title":"Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings","volume":"57","author":"Devereux","year":"1986","journal-title":"Am J Cardiol"},{"key":"2026012114231291400_ehf213909-bib-0011","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1016\/j.jacc.2014.02.536","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association task force on practice guidelines","volume":"63","author":"Nishimura","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2026012114231291400_ehf213909-bib-0012","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1136\/heartjnl-2012-302353","article-title":"Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis","volume":"98","author":"Phelan","year":"2012","journal-title":"Heart"},{"key":"2026012114231291400_ehf213909-bib-0013","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1253\/circj.CJ-20-0110","article-title":"JCS 2020 guideline on diagnosis and treatment of cardiac amyloidosis","volume":"84","author":"Kitaoka","year":"2020","journal-title":"Circ J"},{"key":"2026012114231291400_ehf213909-bib-0014","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/ehjci\/jey042","article-title":"Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI\/ASE\/industry task force to standardize deformation imaging","volume":"19","author":"Badano","year":"2018","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026012114231291400_ehf213909-bib-0015","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1161\/CIRCHEARTFAILURE.114.001276","article-title":"Left atrium in heart failure with preserved ejection fraction: structure, function, and significance","volume":"7","author":"Rossi","year":"2014","journal-title":"Circ Heart Fail"},{"key":"2026012114231291400_ehf213909-bib-0016","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1476-7120-8-14","article-title":"Left atrial longitudinal strain by speckle tracking echocardiography correlates well with left ventricular filling pressures in patients with heart failure","volume":"8","author":"Cameli","year":"2010","journal-title":"Cardiovasc Ultrasound"},{"key":"2026012114231291400_ehf213909-bib-0017","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1002\/ejhf.147","article-title":"Impaired left atrial function in heart failure with preserved ejection fraction","volume":"16","author":"Santos","year":"2014","journal-title":"Eur J Heart Fail"},{"key":"2026012114231291400_ehf213909-bib-0018","author":"Kundu"},{"key":"2026012114231291400_ehf213909-bib-0019","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1161\/CIRCULATIONAHA.113.006242","article-title":"Left ventricular structure and function in transthyretin-related versus light-chain cardiac amyloidosis","volume":"129","author":"Quarta","year":"2014","journal-title":"Circulation"},{"key":"2026012114231291400_ehf213909-bib-0020","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.115.002763","article-title":"Prognostic relevance of left atrial dysfunction in heart failure with preserved ejection fraction","volume":"9","author":"Santos","year":"2016","journal-title":"Circ Heart Fail"},{"key":"2026012114231291400_ehf213909-bib-0021","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1161\/01.CIR.100.4.427","article-title":"Left atrial relaxation and left ventricular systolic function determine left atrial reservoir function","volume":"100","author":"Barbier","year":"1999","journal-title":"Circulation"},{"key":"2026012114231291400_ehf213909-bib-0022","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1161\/CIRCULATIONAHA.104.489187","article-title":"Diagnosis and management of the cardiac amyloidoses","volume":"112","author":"Falk","year":"2005","journal-title":"Circulation"},{"key":"2026012114231291400_ehf213909-bib-0023","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/13506129.2015.1028616","article-title":"Atrial fibrillation in amyloidotic cardiomyopathy: prevalence, incidence, risk factors and prognostic role","volume":"22","author":"Longhi","year":"2015","journal-title":"Amyloid"},{"key":"2026012114231291400_ehf213909-bib-0024","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1093\/eurheartj\/ehx350","article-title":"Unveiling transthyretin cardiac amyloidosis and its predictors among elderly patients with severe aortic stenosis undergoing transcatheter aortic valve replacement","volume":"38","author":"Casta\u00f1o","year":"2017","journal-title":"Eur Heart J"},{"key":"2026012114231291400_ehf213909-bib-0025","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1476-7120-7-6","article-title":"Feasibility and reference values of left atrial longitudinal strain imaging by two-dimensional speckle tracking","volume":"7","author":"Cameli","year":"2009","journal-title":"Cardiovasc Ultrasound"},{"key":"2026012114231291400_ehf213909-bib-0026","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1093\/ejechocard\/jeq175","article-title":"Left atrial function: physiology, assessment, and clinical implications","volume":"12","author":"Blume","year":"2011","journal-title":"Eur J Echocardiogr"},{"key":"2026012114231291400_ehf213909-bib-0027","doi-asserted-by":"crossref","first-page":"113","DOI":"10.2459\/JCM.0000000000000188","article-title":"Left atrial function in cardiac amyloidosis","volume":"17","author":"Di Bella","year":"2016","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"2026012114231291400_ehf213909-bib-0028","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1253\/circj.CJ-16-0364","article-title":"Left atrial morphology, size and function in patients with transthyretin cardiac amyloidosis and primary hypertrophic cardiomyopathy\u2014comparative strain imaging study","volume":"80","author":"de Gregorio","year":"2016","journal-title":"Circ J"},{"key":"2026012114231291400_ehf213909-bib-0029","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0235791","article-title":"Relationships of global longitudinal strain with s\u2018, long-axis systolic excursion, left ventricular length and heart rate","volume":"15","author":"Peverill","year":"2020","journal-title":"PLoS ONE"},{"key":"2026012114231291400_ehf213909-bib-0030","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.116.005066","article-title":"Occult transthyretin cardiac amyloid in severe calcific aortic stenosis: prevalence and prognosis in patients undergoing surgical aortic valve replacement","volume":"9","author":"Treibel","year":"2016","journal-title":"Circ Cardiovasc Imaging"},{"key":"2026012114231291400_ehf213909-bib-0031","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.echo.2015.01.021","article-title":"Intervendor variability of two-dimensional strain using vendor-specific and vendor-independent software","volume":"28","author":"Nagata","year":"2015","journal-title":"J Am Soc Echocardiogr"}],"container-title":["ESC Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ehf2.13909","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ehf2.13909","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/eschf\/article-pdf\/9\/3\/1976\/65668717\/eschf_9_3_1976.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eschf\/article-pdf\/9\/3\/1976\/65668717\/eschf_9_3_1976.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T19:29:01Z","timestamp":1769023741000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eschf\/article\/9\/3\/1976\/8362403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,25]]},"references-count":31,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,3,25]]},"published-print":{"date-parts":[[2022,6,1]]}},"URL":"https:\/\/doi.org\/10.1002\/ehf2.13909","relation":{},"ISSN":["2055-5822"],"issn-type":[{"value":"2055-5822","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,6]]},"published":{"date-parts":[[2022,3,25]]},"assertion":[{"value":"2021-10-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}