{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:41:20Z","timestamp":1786977680611,"version":"build-2736575974"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":1100,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T00:00:00Z","timestamp":1667865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004608","name":"Jiangsu Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["BK20201140"],"award-info":[{"award-number":["BK20201140"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Top Talent Support Program","award":["HB2020119"],"award-info":[{"award-number":["HB2020119"]}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20201140"],"award-info":[{"award-number":["BK20201140"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013111","name":"Tip-top Scientific and Technical Innovative Youth Talents of Guangdong Special Support Program","doi-asserted-by":"publisher","award":["HB2020119"],"award-info":[{"award-number":["HB2020119"]}],"id":[{"id":"10.13039\/501100013111","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This case study aimed to identify rare viral myocarditis combined with encephalitis as a COVID-19 vaccine complication. A 59-year-old male patient with a 2 day history of headache and rapidly progressive cognitive decline, who had received the third dose of COVID-19 vaccine 12 days before, was admitted to our hospital. The patient had no underlying systemic conditions, no prior medical history, and no prior history of COVID-19 infection. The patient was diagnosed with viral myocarditis and encephalitis by two neurologists and two cardiologists after laboratory examination, head computed tomography, and magnetic resonance imaging evaluation. The patient experienced cardiogenic shock and developed severe arrhythmia, resulting in his death 10 h after admission. Clinically suspected lethal viral myocarditis combined with encephalitis in the patient could be related to COVID-19 vaccination. Adverse effects of the Chinese COVID-19 vaccine, especially serious complications, have been uncommon. This case study highlights a rare complication after COVID-19 vaccination that needs high attention.<\/jats:p>","DOI":"10.1002\/ehf2.14229","type":"journal-article","created":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T22:46:07Z","timestamp":1667947567000},"page":"1422-1425","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Clinically Suspected Lethal Viral Myocarditis Combined with Encephalitis: A COVID-19 Vaccine Complication"],"prefix":"10.1093","volume":"10","author":[{"given":"Junhui","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, 904th Hospital of Joint Logistic Support Force of PLA, Wuxi Clinical College of Anhui Medical University , No. 101 Xingyuan North Road, Liangxi District, Wuxi, 214044, Jiangsu Province ,","place":["China"]},{"name":"Department of Human Anatomy and Neurobiology, School of Basic Medical Science, Central South University , Changsha, Hunan Province ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Emergency, 904th Hospital of Joint Logistic Support Force of PLA, Wuxi Clinical College of Anhui Medical University , Wuxi, Jiangsu Province ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunlei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, 904th Hospital of Joint Logistic Support Force of PLA, Wuxi Clinical College of Anhui Medical University , No. 101 Xingyuan North Road, Liangxi District, Wuxi, 214044, Jiangsu Province ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, 904th Hospital of Joint Logistic Support Force of PLA, Wuxi Clinical College of Anhui Medical University , Wuxi ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuanghua","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, 904th Hospital of Joint Logistic Support Force of PLA, Wuxi Clinical College of Anhui Medical University , No. 101 Xingyuan North Road, Liangxi District, Wuxi, 214044, Jiangsu Province ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, 904th Hospital of Joint Logistic Support Force of PLA, Wuxi Clinical College of Anhui Medical University , No. 101 Xingyuan North Road, Liangxi District, Wuxi, 214044, Jiangsu Province ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,11,8]]},"reference":[{"key":"2026012114113944000_ehf214229-bib-0001","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.2217\/fon-2021-1248","article-title":"Efficacy and safety profile of COVID-19 vaccine in cancer patients: a prospective, multicenter cohort study","volume":"18","author":"Yasin","year":"2022","journal-title":"Future Oncol"},{"key":"2026012114113944000_ehf214229-bib-0002","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1161\/CIRCRESAHA.122.319954","article-title":"Cerebrovascular complications of COVID-19 and COVID-19 vaccination","volume":"130","author":"De Michele","year":"2022","journal-title":"Circ Res"},{"key":"2026012114113944000_ehf214229-bib-0003","doi-asserted-by":"crossref","first-page":"517","DOI":"10.15585\/mmwr.mm7114e1","article-title":"Cardiac complications after SARS-CoV-2 infection and mRNA COVID-19 vaccination\u2014PCORnet, United States, January 2021\u2013January 2022","volume":"71","author":"Block","year":"2022","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2026012114113944000_ehf214229-bib-0004","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMc2009787","article-title":"Large-vessel stroke as a presenting feature of Covid-19 in the young","volume":"382","author":"Oxley","year":"2020","journal-title":"N Engl J Med"},{"key":"2026012114113944000_ehf214229-bib-0005","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1161\/CIRCULATIONAHA.121.055891","article-title":"Myocarditis temporally associated with COVID-19 vaccination","volume":"144","author":"Rosner","year":"2021","journal-title":"Circulation"},{"key":"2026012114113944000_ehf214229-bib-0006","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1001\/jamacardio.2022.0583","article-title":"SARS-CoV-2 vaccination and myocarditis in a Nordic cohort study of 23 million residents","volume":"7","author":"Karlstad","year":"2022","journal-title":"JAMA Cardiol"},{"key":"2026012114113944000_ehf214229-bib-0007","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1186\/s12879-022-07186-9","article-title":"Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature","volume":"22","author":"Moslemi","year":"2022","journal-title":"BMC Infect Dis"},{"key":"2026012114113944000_ehf214229-bib-0008","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1038\/s41591-022-01794-3","article-title":"China can prepare to end its zero-COVID policy","volume":"28","author":"Chen","year":"2022","journal-title":"Nat Med"}],"container-title":["ESC Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ehf2.14229","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ehf2.14229","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/eschf\/article-pdf\/10\/2\/1422\/65051515\/eschf_10_2_1422.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eschf\/article-pdf\/10\/2\/1422\/65051515\/eschf_10_2_1422.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T19:12:54Z","timestamp":1769022774000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eschf\/article\/10\/2\/1422\/8304900"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,8]]},"references-count":8,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,11,8]]},"published-print":{"date-parts":[[2023,4,1]]}},"URL":"https:\/\/doi.org\/10.1002\/ehf2.14229","relation":{},"ISSN":["2055-5822"],"issn-type":[{"value":"2055-5822","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,4]]},"published":{"date-parts":[[2022,11,8]]},"assertion":[{"value":"2022-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}