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Drug-induced immune haemolytic anaemia is an unusual drug-adverse event. Furosemide-induced haemolysis is even rarer. This case report presents a 91-year-old male who developed acute haemolytic anaemia 3 days after initiating furosemide to treat myocardial infarction complicated with acute decompensated heart failure. He had increased lactate dehydrogenase and unconjugated bilirubin with undetectable haptoglobin, which indicated the destruction of red blood cells. Other causes for haemolytic anaemia, including hereditary, microangiopathic haemolytic anaemia, and paroxysmal nocturnal haemoglobinuria, were also excluded. He improved with drug cessation and a short course of glucocorticoids. This report aims to raise awareness of this rare complication caused by commonly prescribed drugs. Despite a negative result of a direct antiglobulin test, physicians must remain suspicious of drug-induced immune haemolytic anaemia in unclear cases of haemolysis.<\/jats:p>","DOI":"10.1002\/ehf2.14299","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T19:18:33Z","timestamp":1674069513000},"page":"1449-1453","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Furosemide-Induced Haemolytic Anaemia in an Extreme Elderly Patient"],"prefix":"10.1093","volume":"10","author":[{"given":"I-Wei","family":"Ho","sequence":"first","affiliation":[{"name":"Department of Medicine, Taipei Veterans General Hospital , Taipei ,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4217-8734","authenticated-orcid":false,"given":"Chin-Chou","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital , Taipei ,","place":["Taiwan"]},{"name":"School of Medicine, National Yang Ming Chiao Tung University , Taipei ,","place":["Taiwan"]},{"name":"Institute of Pharmacology, National Yang Ming Chiao Tung University , Taipei ,","place":["Taiwan"]},{"name":"Cardiovascular Research Center, National Yang Ming Chiao Tung University , Taipei ,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,1,18]]},"reference":[{"key":"2026012114112899800_ehf214299-bib-0001","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.jacc.2019.12.059","article-title":"Diuretic therapy for patients with heart failure: JACC state-of-the-art review","volume":"75","author":"Felker","year":"2020","journal-title":"J Am Coll 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