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Outcomes included a composite of (i) major adverse events (need for extracorporeal membrane oxygenation, ventricular assist device, orthotopic heart transplantation, or death) or (ii) recurrent heart failure hospitalization. RV function was obtained from echocardiogram reports. In total, 229 women (1993\u20132017) met criteria for PPCM. Mean age was 32.4 \u00b1 6.8 years, 28% were of African descent, 50 (22%) had RV dysfunction, and 38 (17%) had PASP \u2265 30 mmHg. After a median follow-up of 3.4 years (interquartile range 1.0\u20138.8), 58 (25%) experienced the composite outcome of adverse events. African descent, family history of cardiomyopathy, LVEF, and PASP were significant predictors of RV dysfunction. Using Cox proportional hazards models, we found that women with RV dysfunction were three times more likely to experience the adverse composite outcome: hazard ratio 3.21 (95% confidence interval: 1.11\u20139.28), P = 0.03, in a multivariable model adjusting for age, race, body mass index, preeclampsia, hypertension, diabetes, kidney disease, and LVEF. Women with PASP \u2265 30 mmHg had a lower probability of survival free from adverse events (log-rank P = 0.04).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>African descent and family history of cardiomyopathy were significant predictors of RV dysfunction. RV dysfunction and elevated PASP were significantly associated with a composite of major adverse cardiac events. This at-risk group may prompt closer monitoring or early referral for advanced therapies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.14583","type":"journal-article","created":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T21:10:44Z","timestamp":1701292244000},"page":"422-432","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical Predictors of Right Ventricular Dysfunction and Association with Adverse Outcomes in Peripartum Cardiomyopathy"],"prefix":"10.1093","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2089-8244","authenticated-orcid":false,"given":"Tasnim F.","family":"Imran","sequence":"first","affiliation":[{"name":"Providence VA Medical Center, Warren Alpert Medical School of Brown University , 830 Chalkstone Ave, Providence, RI, 02809 ,","place":["USA"]},{"name":"Lifespan Cardiovascular Institute, Warren Alpert Medical School of Brown University , Providence, RI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feven","family":"Ataklte","sequence":"additional","affiliation":[{"name":"Providence VA Medical Center, Warren Alpert Medical School of Brown University , 830 Chalkstone Ave, Providence, RI, 02809 ,","place":["USA"]},{"name":"Lifespan Cardiovascular Institute, Warren Alpert Medical School of Brown University , Providence, RI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahnoor","family":"Khalid","sequence":"additional","affiliation":[{"name":"Lifespan Cardiovascular Institute, Warren Alpert Medical School of Brown University , Providence, RI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Lopez","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital and the VA Boston Healthcare System, Harvard Medical School , Boston, MA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donya","family":"Mohebali","sequence":"additional","affiliation":[{"name":"Intermountain Medical Center , Salt Lake City, UT ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie A.","family":"Bello","sequence":"additional","affiliation":[{"name":"Smidt Heart Institute, Cedars Sinai Medical Center , Los Angeles, CA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Michael","family":"Gaziano","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital and the VA Boston Healthcare System, Harvard Medical School , Boston, MA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Djousse","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital and the VA Boston Healthcare System, Harvard Medical School , Boston, MA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt","family":"Arany","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marwa A.","family":"Sabe","sequence":"additional","affiliation":[{"name":"Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 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