{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T11:05:09Z","timestamp":1769079909769,"version":"3.49.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":678,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T00:00:00Z","timestamp":1701907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003497","name":"Bundesbeh\u00f6rden der Schweizerischen Eidgenossenschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006392","name":"Centre Hospitalier Universitaire Vaudois","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004362","name":"Schweizerische Herzstiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003497","name":"Bundesbeh\u00f6rden der Schweizerischen Eidgenossenschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006392","name":"Centre Hospitalier Universitaire Vaudois","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004362","name":"Schweizerische Herzstiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004362","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Outcomes reported for patients with hospitalization for acute heart failure (AHF) treatment vary worldwide. Ethnicity-associated characteristics may explain this observation. This observational study compares characteristics and 1-year outcomes of Kyrgyz and Swiss AHF patients against the background of European Society of Cardiology guidelines-based cardiovascular care established in both countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>The primary endpoint was 1 year all-cause mortality (ACM); the secondary endpoint was 1 year ACM or HF-related rehospitalization. A total of 538 Kyrgyz and 537 Swiss AHF patients were included. Kyrgyz patients were younger (64.0 vs. 83.0 years, P &amp;lt; 0.001); ischaemic or rheumatic heart disease and chronic obstructive pulmonary disease were more prevalent (always P &amp;lt; 0.001). In Swiss patients, smoking, dyslipidaemia, hypertension, and atrial flutter\/fibrillation were more frequent (always P \u2264 0.035); moreover, left ventricular ejection fraction (LVEF) was higher (47% vs. 36%; P &amp;lt; 0.001), and &amp;gt;mild aortic stenosis was more prevalent (P &amp;lt; 0.001). Other valvular pathologies were more prevalent in Kyrgyz patients (P &amp;lt; 0.001). At discharge, more Swiss patients were on vasodilatory treatment (P &amp;lt; 0.006), while mineralocorticoid receptor antagonists (P = 0.001), beta-blockers (P = 0.001), or loop diuretics (P &amp;lt; 0.001) were less often prescribed. In Kyrgyz patients, unadjusted odds for the primary and secondary endpoints were lower [odds ratio (OR) 0.68, 95% confidence interval (CI): 0.51\u20130.90, P = 0.008; OR 0.72, 95% CI: 0.56\u20130.91, P = 0.006, respectively]. After adjustment for age and LVEF, no difference remained (primary endpoint: OR 1.03, 95% CI: 0.71\u20131.49, P = 0.894; secondary endpoint: OR 0.82, 95% CI: 0.60\u20131.12, P = 0.206).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>On the background of identical guidelines, age- and LVEF-adjusted outcomes were not different between Central Asian and Western European AHF patients despite of large ethnical disparity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.14591","type":"journal-article","created":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T20:34:22Z","timestamp":1701981262000},"page":"483-491","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["European Society of Cardiology Guidelines and 1 Year Outcomes of Acute Heart Failure Treatment in Central Asia and Europe"],"prefix":"10.1093","volume":"11","author":[{"given":"Tamila","family":"Abdurashidova","sequence":"first","affiliation":[{"name":"Division of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne , Rue du Bugnon 46, 1001, Lausanne ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University Hospital of Bern, University of Bern , Bern ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Schukraft","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne , Rue du Bugnon 46, 1001, Lausanne ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nisha","family":"Soborun","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne , Rue du Bugnon 46, 1001, Lausanne ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Pitta-Gros","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne , Rue du Bugnon 46, 1001, Lausanne ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Kiko\u00efne","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne , Rue du Bugnon 46, 1001, Lausanne ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henri","family":"Lu","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne , Rue du Bugnon 46, 1001, Lausanne ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zalina","family":"Chazymova","sequence":"additional","affiliation":[{"name":"Cardiac Care Unit, National Center of Cardiology and Internal Medicine , Bishkek ,","place":["Kyrgyzstan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanzaada","family":"Dzhorupbekova","sequence":"additional","affiliation":[{"name":"Department of Statistics, National Center of Cardiology and Internal Medicine , Bishkek ,","place":["Kyrgyzstan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Medet","family":"Beishenkulov","sequence":"additional","affiliation":[{"name":"Cardiac Care Unit, National Center of Cardiology and Internal Medicine , Bishkek ,","place":["Kyrgyzstan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Tzimas","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular Department, Lausanne University Hospital, University of Lausanne , Rue du Bugnon 46, 1001, Lausanne ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Kirsch","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardiovascular Department, Lausanne University Hospital, University of Lausanne , Lausanne ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Vollenweider","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Lausanne University Hospital, University of Lausanne , Lausanne 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