{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:10:14Z","timestamp":1791666614115,"version":"4.3.4"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":113,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:00:00Z","timestamp":1761609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The impact of tricuspid transcatheter edge-to-edge repair (T-TEER) on right ventricular (RV) remodelling remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study focused on characterizing changes in RV ejection fraction (RVEF) following T-TEER and their prognostic implications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with significant tricuspid regurgitation (TR) who underwent T-TEER and cardiac magnetic resonance (CMR) imaging were included. Follow-up CMR was performed within 1 to 3 months after the procedure. Patients were classified by postprocedural RVEF change: decreased (\u2264\u22125%), stable (\u22124% to 4%) or increased (\u22655%). The primary outcome was a composite of all-cause mortality or heart failure hospitalization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 69 patients (median age 78 years; 54% female). RVEF decreased in 32 (46%), was stable in 27 (39%), and increased in 10 (15%). Compared with patients with decreased and stable RVEF, those with increased RVEF had lower baseline RVEF (43% vs. 52% and 50%, respectively, P = 0.007) and lower baseline RV to pulmonary artery coupling (0.78 vs. 1.00 and 1.18, P = 0.045). Pulmonary artery systolic pressure was lower in patients with stable RVEF (42 mmHg vs. 52 mmHg in decreased and 49 mmHg in increased RVEF group, P = 0.048). TR severity was significantly reduced in the decreased and stable RVEF groups (P &amp;lt; 0.001 for both) while it worsened in the increased RVEF group (P = 0.037). After T-TEER, effective RVEF rose significantly in decreased (30% to 35%) and stable (31% to 39%) groups (both P &amp;lt; 0.001) but tended to decline in the increased group (30% to 20%; P = 0.17). During a median follow-up of 1016 days, 16 patients died, and 15 were hospitalized for heart failure. Event rates were lowest in the stable RVEF group and highest in the increased RVEF group (log-rank P = 0.004).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>RV response to T-TEER is heterogeneous, mostly influenced by baseline RV function, RV-PA coupling and TR progression. Only a minority of patients exhibited an increase in RVEF post T-TEER, and these patients showed worsening TR and a poorer prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ehf2.70001","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T15:03:02Z","timestamp":1761663782000},"page":"4451-4462","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Adaptation of Right Ventricular Function Following Tricuspid Transcatheter Edge-To-Edge Repair"],"prefix":"10.1093","volume":"12","author":[{"given":"Sara","family":"Bombace","sequence":"first","affiliation":[{"name":"Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz , Mainz ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Rosch","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz , Mainz ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne R.","family":"Sch\u00f6ber","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz , Mainz ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"von Roeder","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine\/Cardiology, Heart Center Leipzig at Leipzig University , Leipzig ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Schlotter","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz , Mainz ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Philip","family":"Rommel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz , Mainz ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Recha","family":"Blessing","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz , Mainz ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"L\u00fccke","sequence":"additional","affiliation":[{"name":"Diagnostic and Interventional Radiology, University of Leipzig-Heart Center , Leipzig ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Gutberlet","sequence":"additional","affiliation":[{"name":"Diagnostic and Interventional Radiology, 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