{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T23:08:41Z","timestamp":1776208121568,"version":"3.50.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T00:00:00Z","timestamp":1542931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T00:00:00Z","timestamp":1542931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,1,1]]},"DOI":"10.1002\/ejhf.1339","type":"journal-article","created":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T07:49:22Z","timestamp":1542959362000},"page":"125-127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Endothelial Dysfunction and Cellular Repair in Heart Failure with Preserved Ejection Fraction: Response to a Single Maximal Exercise Bout"],"prefix":"10.1093","volume":"21","author":[{"given":"Andreas B.","family":"Gevaert","sequence":"first","affiliation":[{"name":"Laboratory for Cellular and Molecular Cardiology, Research Group Cardiovascular Diseases, Department of Translational Pathophysiological Research, University of Antwerp , Antwerp ,","place":["Belgium"]},{"name":"Research Group Physiopharmacology, University of Antwerp , Antwerp ,","place":["Belgium"]},{"name":"Department of Cardiology and Cardiac Rehabilitation, Antwerp University Hospital (UZA) , Edegem ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Beckers","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiac Rehabilitation, Antwerp University Hospital (UZA) , Edegem ,","place":["Belgium"]},{"name":"Department of Rehabilitation Sciences and Physiotherapy, University of Antwerp , Antwerp ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amaryllis H.","family":"Van Craenenbroeck","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Medicine and Paediatrics, University of Antwerp , Antwerp ,","place":["Belgium"]},{"name":"Department of Nephrology, Antwerp University Hospital (UZA) , Edegem ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrien","family":"Lemmens","sequence":"additional","affiliation":[{"name":"Research Group Physiopharmacology, University of Antwerp , Antwerp ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline M.","family":"Van De Heyning","sequence":"additional","affiliation":[{"name":"Laboratory for Cellular and Molecular Cardiology, Research Group Cardiovascular Diseases, Department of Translational Pathophysiological Research, University of Antwerp , Antwerp ,","place":["Belgium"]},{"name":"Department of Cardiology and Cardiac Rehabilitation, Antwerp University Hospital (UZA) , Edegem ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hein","family":"Heidbuchel","sequence":"additional","affiliation":[{"name":"Laboratory for Cellular and Molecular Cardiology, Research Group Cardiovascular Diseases, Department of Translational Pathophysiological Research, University of Antwerp , Antwerp ,","place":["Belgium"]},{"name":"Department of Cardiology and Cardiac Rehabilitation, Antwerp University Hospital (UZA) , Edegem ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiaan J.","family":"Vrints","sequence":"additional","affiliation":[{"name":"Laboratory for Cellular and Molecular Cardiology, Research Group Cardiovascular Diseases, Department of Translational Pathophysiological Research, University of Antwerp , Antwerp ,","place":["Belgium"]},{"name":"Department of Cardiology and Cardiac Rehabilitation, Antwerp University Hospital (UZA) , Edegem ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emeline M.","family":"Van Craenenbroeck","sequence":"additional","affiliation":[{"name":"Laboratory for Cellular and Molecular Cardiology, Research Group Cardiovascular Diseases, Department of Translational Pathophysiological Research, University of Antwerp , Antwerp ,","place":["Belgium"]},{"name":"Department of Cardiology and Cardiac Rehabilitation, Antwerp University Hospital (UZA) , Edegem ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,11,23]]},"reference":[{"key":"2026011721282840800_ejhf1339-bib-0001","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/ejhf.735","article-title":"The future of pleiotropic therapy in heart failure. Lessons from the benefits of exercise training on endothelial function","volume":"19","author":"De Keulenaer","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"2026011721282840800_ejhf1339-bib-0002","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jacc.2013.02.092","article-title":"A novel paradigm for heart failure with preserved ejection fraction","volume":"62","author":"Paulus","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"2026011721282840800_ejhf1339-bib-0003","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1002\/ejhf.1059","article-title":"An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology","volume":"20","author":"Louren\u00e7o","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"2026011721282840800_ejhf1339-bib-0004","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/4865756","article-title":"Targeting endothelial function to treat heart failure with preserved ejection fraction: the promise of exercise training","volume":"2017","author":"Gevaert","year":"2017","journal-title":"Oxid Med Cell Longev"},{"key":"2026011721282840800_ejhf1339-bib-0005","doi-asserted-by":"crossref","first-page":"H1876","DOI":"10.1152\/ajpheart.00341.2015","article-title":"Effects of aerobic interval training and continuous training on cellular markers of endothelial integrity in coronary artery disease: a SAINTEX-CAD substudy","volume":"309","author":"Van Craenenbroeck","year":"2015","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2026011721282840800_ejhf1339-bib-0006","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/ejhf.592","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"18","author":"Ponikowski","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"2026011721282840800_ejhf1339-bib-0007","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1093\/eurheartj\/ehq058","article-title":"Exercise acutely reverses dysfunction of circulating angiogenic cells in chronic heart failure","volume":"31","author":"Van Craenenbroeck","year":"2010","journal-title":"Eur Heart J"},{"key":"2026011721282840800_ejhf1339-bib-0008","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.jacc.2010.03.077","article-title":"Global cardiovascular reserve dysfunction in heart failure with preserved ejection fraction","volume":"56","author":"Borlaug","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2026011721282840800_ejhf1339-bib-0009","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1177\/2047487314552764","article-title":"Optimising exercise training in prevention and treatment of diastolic heart failure (OptimEx-CLIN): rationale and design of a prospective, randomised, controlled trial","volume":"21","author":"Suchy","year":"2014","journal-title":"Eur J Prev Cardiol"},{"key":"2026011721282840800_ejhf1339-bib-0010","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1016\/j.jacc.2012.07.036","article-title":"Incremental prognostic significance of peripheral endothelial dysfunction in patients with heart failure with normal left ventricular ejection fraction","volume":"60","author":"Akiyama","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"2026011721282840800_ejhf1339-bib-0011","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/ejhf.979","article-title":"Role of cardiopulmonary exercise testing in clinical stratification in heart failure. A position paper from the Committee on Exercise Physiology and Training of the Heart Failure Association of the European Society of Cardiology","volume":"20","author":"Corr\u00e0","year":"2018","journal-title":"Eur J Heart Fail"}],"container-title":["European Journal of Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fejhf.1339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/21\/1\/125\/66196499\/eurjhf_21_1_125.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/21\/1\/125\/66196499\/eurjhf_21_1_125.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T02:28:43Z","timestamp":1768703323000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjhf\/article\/21\/1\/125\/8408129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,23]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,11,23]]},"published-print":{"date-parts":[[2019,1,1]]}},"URL":"https:\/\/doi.org\/10.1002\/ejhf.1339","relation":{},"ISSN":["1388-9842","1879-0844"],"issn-type":[{"value":"1388-9842","type":"print"},{"value":"1879-0844","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,1]]},"published":{"date-parts":[[2018,11,23]]},"assertion":[{"value":"2018-08-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}