{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T04:27:10Z","timestamp":1790483230626,"version":"4.1.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T00:00:00Z","timestamp":1582156800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T00:00:00Z","timestamp":1582156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100014477","name":"National Health Insurance","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014477","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005630","name":"French Society of Cardiology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005630","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005630","name":"Soci\u00e9t\u00e9 Fran\u00e7aise de Cardiologie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005630","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014477","name":"National Health Insurance Administration","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014477","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005630","name":"Soci\u00e9t\u00e9 Fran\u00e7aise de Cardiologie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005630","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005630","name":"Soci\u00e9t\u00e9 Fran\u00e7aise de Cardiologie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005630","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Few studies describe recent changes in the prevalence, management, and outcomes of cardiogenic shock (CS) patients complicating acute myocardial infarction (AMI) in the era of widespread use of invasive strategies. The aim of the present study was to analyse trends observed in CS complicating AMI over the past 10\u2009years, focusing on the timing of CS occurrence (i.e. primary CS, CS on admission vs. secondary CS, CS developed subsequently during hospitalization).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Three nationwide French registries conducted and designed to evaluate AMI management and outcomes in \u2018real-life\u2019 practice included consecutive AMI patients (n = 9951) admitted to intensive cardiovascular care units (ICCUs) over a 1-month period, 5\u2009years apart. The prevalence of CS complicating AMI decreased from 2005 to 2015: 5.9%, mean age 74.1\u2009\u00b1\u200912.7 in 2005; 4.0%, mean age 73.9\u2009\u00b1\u200912.7 in 2010, 2.8%, mean age 71.1\u2009\u00b1\u200915.0 in 2015 (P\u2009&amp;lt;\u20090.001). It decreased for both primary (1.8% to 1.0%) and secondary CS (4.1% to 1.8%). The profile of CS patients also changed over time with more patients presenting out-of-hospital cardiac arrest. In both primary and secondary CS, the use of percutaneous coronary intervention increased markedly over time, as did the use of mechanical ventilation and cardiac assist devices. Over the 10-year period, in-hospital mortality remained unchanged for both primary CS (41.8% to 37.8%) or secondary CS (57.3% to 58.8%). However, 1-year mortality decreased in patients with primary CS (from 60% to 37.8%, P =\u20090.038), and remained unchanged in patients developing secondary CS (from 64.5% to 69.1%, P =\u20090.731).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cardiogenic shock complicating AMI has become less frequent but, if present, CS, and particularly secondary CS, carries a very high mortality, which has not substantially improved over the past 10\u2009years, in spite of the more frequent use of invasive strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejhf.1750","type":"journal-article","created":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T10:53:27Z","timestamp":1582196007000},"page":"664-672","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":146,"title":["Trends in Cardiogenic Shock Complicating Acute Myocardial Infarction"],"prefix":"10.1093","volume":"22","author":[{"given":"Nadia","family":"Aissaoui","sequence":"first","affiliation":[{"name":"Department of Critical Care, Assistance Publique-H\u00f4pitaux de Paris (APHP), H\u00f4pital Europ\u00e9en Georges Pompidou (HEGP) , Paris ,","place":["France"]},{"name":"Faculty of Medicine, University Paris Descartes , Paris ,","place":["France"]},{"name":"INSERM U970, Paris Cardiovascular Research Center PARCC , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Puymirat","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University Paris Descartes , Paris ,","place":["France"]},{"name":"Department of Cardiology, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Europ\u00e9en Georges Pompidou , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9ment","family":"Delmas","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, CHU Rangueil , Toulouse ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Ortuno","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Assistance Publique-H\u00f4pitaux de Paris (APHP), H\u00f4pital Europ\u00e9en Georges Pompidou (HEGP) , Paris ,","place":["France"]},{"name":"Faculty of Medicine, University Paris Descartes , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Durand","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology and Clinical Research Platform of East of Paris (URCEST-CRB-CRC), APHP-Sorbonne Universit\u00e9, H\u00f4pital St Antoine , Paris ,","place":["France"]},{"name":"H\u00f4pital Charles Nicolle , Rouen ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Bataille","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, CHU Rangueil , Toulouse ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Drouet","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology and Clinical Research Platform of East of Paris (URCEST-CRB-CRC), APHP-Sorbonne Universit\u00e9, H\u00f4pital St Antoine , Paris ,","place":["France"]},{"name":"H\u00f4pital Charles Nicolle , Rouen ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Bonello","sequence":"additional","affiliation":[{"name":"CHU H\u00f4pital Nord , Marseille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Bonnefoy-Cudraz","sequence":"additional","affiliation":[{"name":"CHU de Lyon, Universit\u00e9 de Lyon 1 , Lyon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Lesmeles","sequence":"additional","affiliation":[{"name":"CHRU Lille , Lille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Guerot","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Assistance Publique-H\u00f4pitaux de Paris (APHP), H\u00f4pital Europ\u00e9en Georges Pompidou (HEGP) , Paris ,","place":["France"]},{"name":"Faculty of Medicine, University Paris Descartes , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois","family":"Schiele","sequence":"additional","affiliation":[{"name":"CHU Besancon \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tabassome","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology and Clinical Research Platform of East of Paris (URCEST-CRB-CRC), APHP-Sorbonne Universit\u00e9, H\u00f4pital St Antoine , Paris ,","place":["France"]},{"name":"Unit\u00e9 INSERM U-1148 , Paris ,","place":["France"]},{"name":"FACT (French Alliance for Cardiovascular Trials), An F-CRIN Network , Paris ,","place":["France"]},{"name":"Sorbonne-Universit\u00e9, UPMC , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Danchin","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University Paris Descartes , Paris ,","place":["France"]},{"name":"Department of Cardiology, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Europ\u00e9en Georges Pompidou , Paris ,","place":["France"]},{"name":"FACT (French Alliance for Cardiovascular Trials), An F-CRIN Network , Paris 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