{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:01:21Z","timestamp":1789005681893,"version":"build-2803163510"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T00:00:00Z","timestamp":1615248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["RO1 HL128526"],"award-info":[{"award-number":["RO1 HL128526"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009550","name":"Universiteit Hasselt","doi-asserted-by":"publisher","award":["BOF19PD04"],"award-info":[{"award-number":["BOF19PD04"]}],"id":[{"id":"10.13039\/501100009550","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007229","name":"Special Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007229","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001491","name":"Belgian American Educational Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001491","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Heart Fail"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To investigate the prognostic value of diagnostic scores for heart failure (HF) with preserved ejection fraction (HFpEF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>\n                      Consecutive patients with HFpEF admitted for unequivocal decompensated HF treated with intravenous loop diuretics were evaluated (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0443; mean age 78\u2009\u00b1\u200912\u2009years; 60% women). The HFA\u2010PEFF and H\n                      <jats:sub>2<\/jats:sub>\n                      FPEF scores were calculated for all patients with echocardiography data available within 1\u2009year and the population was stratified according to HFA\u2010PEFF scores 2\u20134 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a079), 5 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a093), or 6 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0271) and H\n                      <jats:sub>2<\/jats:sub>\n                      FPEF score probabilities &lt;90% (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a080), 90\u201395% (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a061), and 96\u2013100% (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0293). HF readmission rates (95% confidence intervals) increased from 28.9 (22.7\u201335.0) per 100 patient\u2010years in HFA\u2010PEFF 2\u20134 to 46.0 (38.5\u201353.5) in HFA\u2010PEFF 5 and 45.0 (40.1\u201349.8) in HFA\u2010PEFF 6. Similarly, HF readmission rates increased with increasing H\n                      <jats:sub>2<\/jats:sub>\n                      FPEF probability: &lt;0.90 [31.8 (25.3\u201338.2) per 100 patient\u2010years], 0.90\u20130.95 [41.5 (32.9\u201350.1)], and 0.96\u20131.00 [45.9 (41.2\u201350.6]. Median survival was 65\u2009months (36\u201389\u2009months) in HFA\u2010PEFF score 2\u20134, 45\u2009months (26\u201359\u2009months) in HFA\u2010PEFF score 5, and 28\u2009months (22\u201342\u2009months) in HFA\u2010PEFF score 6 (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), while the hazard ratio (95% confidence interval) for all\u2010cause mortality was 1.16 (1.02\u20131.32) per 0.10 increase in H\n                      <jats:sub>2<\/jats:sub>\n                      FPEF probability.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among patients hospitalized with HFpEF, higher HFpEF probability according to diagnostic scores is associated with increased risk of subsequent HF readmissions and all\u2010cause mortality.<\/jats:p>\n                  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