{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:50:12Z","timestamp":1792615812808,"version":"4.5.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T00:00:00Z","timestamp":1629849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["ERC\u20102016\u2010StG\u2014715732"],"award-info":[{"award-number":["ERC\u20102016\u2010StG\u2014715732"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Heart Fail"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Hypertensive disorders occur in women with peripartum cardiomyopathy (PPCM). How often hypertensive disorders co\u2010exist, and to what extent they impact outcomes, is less clear. We describe differences in phenotype and outcomes in women with PPCM with and without hypertensive disorders during pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>\n                      The European Society of Cardiology EURObservational Research Programme PPCM Registry enrolled women with PPCM from 2012\u20132018. Three groups were examined: (i) women without hypertension (PPCM\u2010noHTN); (ii) women with hypertension but without pre\u2010eclampsia (PPCM\u2010HTN); (iii) women with pre\u2010eclampsia (PPCM\u2010PE). Maternal (6\u2010month) and neonatal outcomes were compared. Of 735 women included, 452 (61.5%) had PPCM\u2010noHTN, 99 (13.5%) had PPCM\u2010HTN and 184 (25.0%) had PPCM\u2010PE. Compared to women with PPCM\u2010noHTN, women with PPCM\u2010PE had more severe symptoms (New York Heart Association class IV in 44.4% vs. 29.9%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), more frequent signs of heart failure (pulmonary rales in 70.7% vs. 55.4%,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.002), a higher baseline left ventricular ejection fraction (LVEF) (32.7% vs. 30.7%,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.005) and a smaller left ventricular end\u2010diastolic diameter (57.4\u2009\u00b1\u20096.7\u2009mm vs. 59.8\u2009\u00b1\u20098.1\u2009mm,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.001). There were no differences in the frequencies of death from any cause, rehospitalization for any cause, stroke, or thromboembolic events. Compared to women with PPCM\u2010noHTN, women with PPCM\u2010PE had a greater likelihood of left ventricular recovery (LVEF\u2009\u2265\u200950%) (adjusted odds ratio 2.08, 95% confidence interval 1.21\u20133.57) and an adverse neonatal outcome (composite of termination, miscarriage, low birth weight or neonatal death) (adjusted odds ratio 2.84, 95% confidence interval 1.66\u20134.87).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Differences exist in phenotype, recovery of cardiac function and neonatal outcomes according to hypertensive status in women with PPCM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejhf.2264","type":"journal-article","created":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T04:40:27Z","timestamp":1623386427000},"page":"2058-2069","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Hypertensive disorders in women with peripartum cardiomyopathy: insights from the\n                    <scp>ESC<\/scp>\n                    EORP PPCM Registry"],"prefix":"10.1093","volume":"23","author":[{"given":"Alice M.","family":"Jackson","sequence":"first","affiliation":[{"name":"BHF Cardiovascular Research Centre University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark C.","family":"Petrie","sequence":"additional","affiliation":[{"name":"BHF Cardiovascular Research Centre University of Glasgow  Glasgow UK"},{"name":"Golden Jubilee National Hospital  Clydebank UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Frogoudaki","sequence":"additional","affiliation":[{"name":"Second Cardiology Department Attikon University Hospital  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Laroche","sequence":"additional","affiliation":[{"name":"EORP, European Society of Cardiology  Sophia Antipolis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Finn","family":"Gustafsson","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassem","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Cardiology North Cumbria University Hospital  Carlisle UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Mebazaa","sequence":"additional","affiliation":[{"name":"UMR 942 Inserm\u00a0\u2013\u00a0MASCOT; University of Paris APHP Saint Louis Lariboisi\u00e8re University Hospitals, Department of Anesthesia\u2010Burn\u2010Critical Care  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Imperial College School of Medicine, Chelsea and Westminster Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petar M.","family":"Seferovic","sequence":"additional","affiliation":[{"name":"University of Belgrade Faculty of Medicine Serbian Academy of Sciences and Arts  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Regitz\u2010Zagrosek","sequence":"additional","affiliation":[{"name":"Berlin Institute of Gender in Medicine (GiM)\u00a0\u2013\u00a0Charit\u00e9 Universit\u00e4tsmedizin  Berlin 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Cardiovascular Medicine, Faculty of Medicine Assiut University  Assiut Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorel","family":"Goland","sequence":"additional","affiliation":[{"name":"Kaplan Medical Center, Rehovot Hebrew University  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albertino","family":"Damasceno","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Eduardo Mondlane University  Maputo Mozambique"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamilu","family":"Karaye","sequence":"additional","affiliation":[{"name":"Department of Medicine Bayero University &amp; Aminu Kano Teaching Hospital  Kano Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan A.","family":"Farhan","sequence":"additional","affiliation":[{"name":"Scientific Council of Cardiology, Iraqi Board for Medical Specializations, Baghdad Heart Center  Baghdad 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