{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T19:03:33Z","timestamp":1788894213858,"version":"build-2803163510"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32HL007604"],"award-info":[{"award-number":["T32HL007604"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005292","name":"Brigham and Women's Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005292","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32HL007604"],"award-info":[{"award-number":["T32HL007604"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005292","name":"Brigham and Women's Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005292","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To describe outcomes associated with bridging strategies in patients with acute decompensated heart failure-related cardiogenic shock (ADHF-CS) bridged to durable left ventricular assist device (LVAD) or heart transplantation (HTx).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Durable LVAD or HTx recipients from 2014 to 2019 with pre-operative ADHF-CS were identified in the Society of Thoracic Surgeons Adult Cardiac Surgery Database and stratified by bridging strategy. The primary outcome was operative or 30-day post-operative mortality. Secondary outcomes included post-operative major bleeding. Exploratory comparisons between bridging strategies and outcomes were performed using overlap weighting with and without covariate adjustment. Among 9783 patients with pre-operative CS, 8777 (89.7%) had ADHF-CS. Medical therapy (n = 5013) was the most common bridging strategy, followed by intra-aortic balloon pump (IABP; n = 2816), catheter-based temporary mechanical circulatory support (TMCS; n = 417), and veno-arterial extracorporeal membrane oxygenation (VA-ECMO; n = 465). Mortality was highest in patients bridged with VA-ECMO (22%), followed by catheter-based TMCS (10%), IABP (9%), and medical therapy (7%). Adverse post-operative outcomes were more frequent in LVAD recipients compared with HTx recipients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Among patients with ADHF-CS bridged to HTx or durable LVAD, the highest rates of death and adverse events during index hospitalization were observed in those bridged with VA-ECMO, followed by catheter-based TMCS, IABP, and medical therapy. Patients who received durable LVAD had higher rates of post-operative complications compared with HTx recipients. Prospective trials are needed to define optimal bridging strategies in patients with ADHF-CS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejhf.2762","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T03:30:46Z","timestamp":1672803046000},"page":"425-435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Bridging Strategies and Cardiac Replacement Outcomes in Patients with Acute Decompensated Heart Failure-Related Cardiogenic Shock"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9697-8948","authenticated-orcid":false,"given":"Anubodh S.","family":"Varshney","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Stanford University , Palo Alto, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David D.","family":"Berg","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston, MA ,","place":["USA"]},{"name":"Levine Cardiac Intensive Care Unit and Thrombolysis in Myocardial Infarction (TIMI) Study Group , Boston, MA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohai","family":"Zhou","sequence":"additional","affiliation":[{"name":"Center for Clinical Investigation, Brigham and Women's Hospital , Boston, MA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Sinnenberg","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania , Philadelphia, PA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer","family":"Hirji","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Brigham and Women's Hospital and Harvard Medical School , Boston, MA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ersilia M.","family":"DeFilippis","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Columbia University Irving Medical Center , New York, NY ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hari R.","family":"Mallidi","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Brigham and Women's Hospital and Harvard Medical School , Boston, MA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Morrow","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston, MA ,","place":["USA"]},{"name":"Levine Cardiac Intensive Care Unit and Thrombolysis in Myocardial Infarction (TIMI) Study Group , Boston, MA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Rinewalt","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Surgery, AdventHealth , Orlando, FL ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1012-7710","authenticated-orcid":false,"given":"Michael M.","family":"Givertz","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston, MA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,1,19]]},"reference":[{"key":"2026010913120325300_ejhf2762-bib-0001","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0140-6736(20)31047-3","article-title":"Temporary circulatory support for cardiogenic shock","volume":"396","author":"Combes","year":"2020","journal-title":"Lancet"},{"key":"2026010913120325300_ejhf2762-bib-0002","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1002\/ejhf.1922","article-title":"Epidemiology, pathophysiology and contemporary management of cardiogenic shock \u2013 a position statement from the Heart Failure Association of the European Society of Cardiology","volume":"22","author":"Chioncel","year":"2020","journal-title":"Eur J Heart Fail"},{"key":"2026010913120325300_ejhf2762-bib-0003","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCOUTCOMES.119.005618","article-title":"Epidemiology of shock in contemporary cardiac intensive care units","volume":"12","author":"Berg","year":"2019","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"2026010913120325300_ejhf2762-bib-0004","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.jchf.2020.09.005","article-title":"A standardized and comprehensive approach to the management of cardiogenic shock","volume":"8","author":"Tehrani","year":"2020","journal-title":"JACC Heart Fail"},{"key":"2026010913120325300_ejhf2762-bib-0005","first-page":"401","article-title":"Epidemiology and causes of cardiogenic shock","volume":"27","author":"Berg","year":"2021","journal-title":"Curr Opin Crit Care"},{"key":"2026010913120325300_ejhf2762-bib-0006","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ahj.2020.10.054","article-title":"Shock in the cardiac intensive care unit: changes in epidemiology and prognosis over time","volume":"232","author":"Jentzer","year":"2021","journal-title":"Am Heart J"},{"key":"2026010913120325300_ejhf2762-bib-0007","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.healun.2019.11.009","article-title":"Longitudinal impact of temporary mechanical circulatory support on durable ventricular assist device outcomes: an IMACS registry propensity matched analysis","volume":"39","author":"Hernandez-Montfort","year":"2020","journal-title":"J Heart Lung Transplant"},{"key":"2026010913120325300_ejhf2762-bib-0008","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.healun.2019.04.003","article-title":"Post-transplant outcome in patients bridged to transplant with temporary mechanical circulatory support devices","volume":"38","author":"Yin","year":"2019","journal-title":"J Heart Lung Transplant"},{"key":"2026010913120325300_ejhf2762-bib-0009","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1001\/jamacardio.2020.0692","article-title":"Use of temporary mechanical circulatory support for management of cardiogenic shock before and after the United Network for Organ Sharing donor heart allocation system changes","volume":"5","author":"Varshney","year":"2020","journal-title":"JAMA Cardiol"},{"key":"2026010913120325300_ejhf2762-bib-0010","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.healun.2020.08.012","article-title":"Outcomes in the 2018 UNOS donor heart allocation system: a perspective on disparate analyses","volume":"39","author":"Varshney","year":"2020","journal-title":"J Heart Lung Transplant"},{"key":"2026010913120325300_ejhf2762-bib-0011","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1001\/jamacardio.2020.4909","article-title":"Evolving trends in adult heart transplant with the 2018 heart allocation policy change","volume":"6","author":"Kilic","year":"2021","journal-title":"JAMA Cardiol"},{"key":"2026010913120325300_ejhf2762-bib-0012","volume-title":"Adult heart allocation - OPTN [Internet]"},{"key":"2026010913120325300_ejhf2762-bib-0013","first-page":"1419","article-title":"The Society of Thoracic Surgeons 2018 adult cardiac surgery risk models: Part 2 \u2013 statistical methods and results","volume":"105","author":"O'Brien","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"2026010913120325300_ejhf2762-bib-0014","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1001\/jama.2020.7819","article-title":"Overlap weighting: a propensity score method that mimics attributes of a randomized clinical trial","volume":"323","author":"Thomas","year":"2020","journal-title":"JAMA"},{"key":"2026010913120325300_ejhf2762-bib-0015","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.120.007924","article-title":"Clinical outcomes associated with acute mechanical circulatory support utilization in heart failure related cardiogenic shock","volume":"14","author":"Hernandez-Montfort","year":"2021","journal-title":"Circ Heart Fail"},{"key":"2026010913120325300_ejhf2762-bib-0016","doi-asserted-by":"crossref","first-page":"2956","DOI":"10.1016\/j.jacc.2020.10.036","article-title":"Transition from temporary to durable circulatory support systems","volume":"76","author":"Saeed","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"2026010913120325300_ejhf2762-bib-0017","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1016\/j.jacc.2020.04.037","article-title":"Survival after heart transplantation in patients bridged with mechanical circulatory support","volume":"75","author":"Moonsamy","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"2026010913120325300_ejhf2762-bib-0018","article-title":"Extracorporeal membrane oxygenation as a bridge to durable mechanical circulatory support: an analysis of the STS-INTERMACS database","volume":"13","author":"Loyaga-Rendon","year":"2020","journal-title":"Circ Heart Fail"},{"key":"2026010913120325300_ejhf2762-bib-0019","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.019376","article-title":"Intra-aortic balloon pump as a bridge to durable left ventricular assist device","volume":"10","author":"Brown","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"2026010913120325300_ejhf2762-bib-0020","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.120.006971","article-title":"Intra-aortic balloon pump bridging to heart transplantation: impact of the 2018 allocation change","volume":"13","author":"Huckaby","year":"2020","journal-title":"Circ Heart Fail"},{"key":"2026010913120325300_ejhf2762-bib-0021","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.cardfail.2021.08.014","article-title":"De novo vs acute-on-chronic presentations of heart failure-related cardiogenic shock: insights from the Critical Care Cardiology Trials Network registry","volume":"27","author":"Bhatt","year":"2021","journal-title":"J Card Fail"},{"key":"2026010913120325300_ejhf2762-bib-0022","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jchf.2020.12.012","article-title":"ECMO as a bridge to left ventricular assist device or heart transplantation","volume":"9","author":"DeFilippis","year":"2021","journal-title":"JACC Heart Fail"},{"key":"2026010913120325300_ejhf2762-bib-0023","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1056\/NEJMoa021744","article-title":"Chronic renal failure after transplantation of a nonrenal organ","volume":"349","author":"Ojo","year":"2003","journal-title":"N Engl J Med"}],"container-title":["European Journal of Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejhf.2762","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ejhf.2762","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/25\/3\/425\/65552403\/eurjhf_25_3_425.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/25\/3\/425\/65552403\/eurjhf_25_3_425.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:15:08Z","timestamp":1767982508000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjhf\/article\/25\/3\/425\/8343598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,19]]},"references-count":23,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,1,19]]},"published-print":{"date-parts":[[2023,3,1]]}},"URL":"https:\/\/doi.org\/10.1002\/ejhf.2762","relation":{},"ISSN":["1388-9842","1879-0844"],"issn-type":[{"value":"1388-9842","type":"print"},{"value":"1879-0844","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,3]]},"published":{"date-parts":[[2023,1,19]]},"assertion":[{"value":"2022-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}